Hotels near Lewis and Clark Interpretive Center
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Our top choices for Lewis and Clark Interpretive Center hotels

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City6.2 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (488)
The price is RM454
RM503 total
includes taxes & fees
11 Jan - 12 Jan 2026

Drury Inn & Suites St. Louis Collinsville
Drury Inn & Suites St. Louis Collinsville15.4 km from Lewis and Clark Interpretive Center
9.6 out of 10, Exceptional, (1003)
The price is RM397
RM456 total
includes taxes & fees
11 Jan - 12 Jan 2026

Holiday Inn Express & Suites Edwardsville by IHG
Holiday Inn Express & Suites Edwardsville by IHG10.9 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (823)
The price is RM470
RM540 total
includes taxes & fees
4 Jan - 5 Jan 2026

Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach6.8 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (806)
The price is RM346
RM384 total
includes taxes & fees
4 Jan - 5 Jan 2026

8.6 out of 10, Excellent, (196)
The price is RM320
RM392 total
includes taxes & fees
5 Jan - 6 Jan 2026

Hampton Inn & Suites St. Louis/Alton
Hampton Inn & Suites St. Louis/Alton14 km from Lewis and Clark Interpretive Center
9.0 out of 10, Wonderful, (644)
The price is RM462
RM526 total
includes taxes & fees
11 Jan - 12 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Lewis and Clark Interpretive Center Hotel Reviews

Pear Tree Inn St. Louis Near Union Station
10/10 Excellent












































































