A riverside walkway with cyclists, a bridge, and modern buildings.

Greenville Spa Hotels

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Check availability on Greenville Hotels with Spa

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for Greenville hotels with a spa

A spa room with two beds, a mural, and a reception desk.
A modern interior with a fireplace, plush seating, and a stone accent wall.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.
A modern interior with a stone fireplace, seating areas, and a unique ceiling design.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
  • Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
RM1,589
RM1,800 total
includes taxes & fees
4 Oct - 5 Oct
Grand Bohemian Lodge Greenville, Autograph Collection
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.
A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.
A modern interior with a large window, a chandelier, a dining area, and a hallway leading to a door.
A large, two-story house with a symmetrical facade, large windows, and a central entrance.

2. Hotel Hartness

Hotel Hartness
Greenville
  • Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
RM622
RM839 total
includes taxes & fees
4 Oct - 5 Oct
Hotel Hartness
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.
A bar with a large window view of mountains and a chandelier.
A swimming pool with lounge chairs and a building with balconies.

3. Hotel Domestique

Hotel Domestique
Travelers Rest
  • Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
RM1,712
RM1,883 total
includes taxes & fees
4 Oct - 5 Oct
Hotel Domestique
A wooden deck with chairs, surrounded by trees with autumn foliage.
A wooden deck with a spiral glass sculpture, potted plants, and a bench.
A hotel with a covered front porch, steps leading up to the entrance, and snow-covered bushes.
A dining table set for two with a view of a forested landscape through large windows.

4. The Orchard Inn

The Orchard Inn
Saluda
  • Enjoy a couples massage or solo Swedish retreat in this peaceful bed & breakfast with gardens and a 24-hour gym.
RM1,222
RM1,341 total
includes taxes & fees
1 Nov - 2 Nov
The Orchard Inn
View all properties

Choose what matters most at spa hotels in Greenville

Pool
Hot tub
Breakfast included
4 stars
Gym

Top Greenville Hotel Reviews

Hilton Greenville

Hilton Greenville

10/10 Excellent
"Food was awful and when they asked we told them but they did not do anything about it. I paid for $50 worth of food we didn’t eat."
Jasmine 2-night trip
Posted 13 hours ago
Hilton Greenville

Frequently asked questions

Looking to holiday at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travellers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your holiday. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness centre and a restaurant. Enjoy a massage at The Spa at Grand Bohemian. Another popular spa hotel in Greenville is Hotel Hartness.
How many spa hotels will I find in Greenville?
Among Expedia's 702 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children's Museum of the Upstate and Bon Secours Wellness Arena. If you have some spare time during your trip, you might want to check out Greenville Zoo and Fluor Field at the West End.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas which offer services including facials and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.

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