Top 10 Greater South Side Hotels of 2026

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Compare popular hotels in Greater South Side

Property	Property class	Guest rating
Hampton Inn Des Moines-Airport	2.5 star property	8.8 Excellent 1,005 reviews	View
Days Inn & Suites by Wyndham Des Moines Airport	2.0 star property	8.6 Excellent 1,830 reviews	View
Holiday Inn Des Moines-Airport/Conf Center by IHG	3.0 star property	8.4 Very good 683 reviews	View
AmericInn by Wyndham Des Moines Airport	3.0 star property	8.0 Very good 1,004 reviews	View
Quality Inn & Suites Des Moines Airport	2.5 star property	7.6 Good 1,005 reviews	View

Where to stay in Greater South Side

Find the best Greater South Side areas for the activities you enjoy most.

The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

The abundant dining options and live music are top of the list for many visitors to Downtown Des Moines. A stop by 801 Grand or Des Moines Civic Center might round out your trip.

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A city skyline at night with illuminated buildings and a prominent tower.

Court District

Travellers come to Court District for its abundant dining options, and you can see top attractions like Science Center of Iowa and Principal Park while you're in town.

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The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.

Drake

While visiting Drake, you might make a stop by sights like Knapp Center and Des Moines Community Playhouse.

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Historic East Village

Find beautiful government buildings, cultural attractions and a garden oasis in this older section of the city extending along a pretty riverfront.

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A paved road flanked by trees and bushes, leading into the distance.

Southwestern Hills

Though Southwestern Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gray’s Lake Park and Lauridsen Amphitheater.

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Top Greater South Side Hotel Reviews

Sonesta Essential Des Moines

8/10 Good

"This was a great room for our stay in Des Moines. I was curious about the breakfast after reading a few reviews complaining about it, but it was just like all of the other continental breakfasts; waffles, eggs and sausage, juice and coffee, fruit, cereal, muffins and toast, yogurt, cereal etc. The room was clean and the staff was nice and it was a good price."

Country Inn & Suites by Radisson, Des Moines West, IA

8/10 Good

"The hotel was clean and comfortable and our room was spacious. I was not at all happy when we arrived and was told the pet fee was $60 a night. That is ridiculous! We are responsible pet owners and I don’t mind a pet fee but that’s almost half the room rate. We will probably not stay here again."

Stoney Creek Hotel Des Moines - Johnston

8/10 Good

"This is our go to hotel…price is always great, get a voucher for a free drink, hot tub is amazing and their breakfast is always tops…this time they were renovating so banging going on, hot tub down and at breakfast the waffle maker broke and sausage was spoiled. We will go back and hopefully will be all up and running in their newly renovated domain."

Days Inn & Suites by Wyndham Des Moines Airport

8/10 Good

"Stayed there prior to flying out the next morning. Hotel was a great affordable option for somewhere to crash for a night. Room was clean (though just a bit musty), staff was extremely helpful, there was a breakfast before we left and we had the option to leave our car at the hotel and take a shuttle to the airport for a very small daily cost. Would definitely stay again."

Frequently asked questions

What's it like in Greater South Side?

Travellers are sure to enjoy a stay in Des Moines's Greater South Side neighbourhood. Consider a visit to Gray's Lake Park as part of your Greater South Side travel plans.

What's the best accommodation in Greater South Side?

Based on our traveller data, Days Inn & Suites by Wyndham Des Moines Airport is one of the top choices for your stay in Greater South Side. This hotel offers free breakfast and an indoor pool. Other good options for your stay in the neighbourhood include AmericInn by Wyndham Des Moines Airport and Hampton Inn Des Moines-Airport.

How many hotels can I expect to find in Greater South Side?

With 19 Expedia hotels and other accommodation options in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.

If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?

Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Greater South Side.

What is there to do around this Des Moines neighbourhood?

Gray's Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.

Hotels in Greater South Side, Des Moines

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Our top choices for Greater South Side hotels

1. Hampton Inn Des Moines-Airport

2. Holiday Inn Des Moines-Airport/Conf Center by IHG

3. Days Inn & Suites by Wyndham Des Moines Airport

4. AmericInn by Wyndham Des Moines Airport

5. Quality Inn & Suites Des Moines Airport

6. Holiday Inn Express & Suites Des Moines Downtown by IHG

7. Home2 Suites by Hilton Des Moines at Drake University

8. Hotel Fort Des Moines, Curio Collection by Hilton

9. Des Lux Hotel

10. Hampton Inn & Suites Des Moines Downtown

11. Des Moines Marriott Downtown

12. Hilton Des Moines Downtown

13. Comfort Inn & Suites Event Center

14. Embassy Suites Hotel Des Moines Downtown

15. Staybridge Suites Des Moines Downtown by IHG

16. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

17. Fairfield Inn & Suites by Marriott Des Moines Airport

18. Residence Inn Des Moines Downtown

19. Hilton Garden Inn Des Moines Airport

20. Hyatt Place Des Moines/Downtown

Compare popular hotels in Greater South Side

Where to stay in Greater South Side

Downtown Des Moines

Court District

Drake

Historic East Village

Southwestern Hills

Top Greater South Side Hotel Reviews

Sonesta Essential Des Moines

Frequently asked questions

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