A field with a truck and a power line.

Eastern South Dakota Spa Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Eastern South Dakota Hotels with Spa

Tonight
8 Sept - 9 Sept
Tomorrow
9 Sept - 10 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

Our top choices for Eastern South Dakota hotels with a spa

An indoor swimming pool with lounge chairs and a seating area.
A spacious lobby with multiple seating areas, a central bar with multiple screens, and a distinctive ceiling design.
A hotel entrance with a neon sign, a digital display, and a glass door with lights.
A casino with multiple slot machines arranged in rows, a white car displayed prominently, and a ceiling with circular light fixtures.

1. Grand Falls Casino & Golf Resort

Grand Falls Casino & Golf Resort
Larchwood
  • Rejuvenate in a luxury spa sanctuary with 12 treatment rooms and a serene golf course setting for total relaxation.
RM623
RM697 total
includes taxes & fees
9 Sept - 10 Sept
Grand Falls Casino & Golf Resort
A courtyard with outdoor seating, a fire pit, and a building with multiple windows.
A multi-story hotel with a brick facade, multiple windows, and a well-lit entrance.
A modern dining area with a counter, bar, and seating.
An indoor swimming pool with clear glass walls, a basketball hoop, and potted plants.

2. TownePlace Suites by Marriott Sioux Falls

TownePlace Suites by Marriott Sioux Falls
Mall District
  • Welcoming hotel offers daily spa service, indoor hot tub, and 24-hour fitness centre for relaxation.
RM433
RM483 total
includes taxes & fees
13 Sept - 14 Sept
TownePlace Suites by Marriott Sioux Falls
A room with a massage table, two chairs, a small table with a bottle and a tissue, and a window with blinds.
A spacious living area with a round wooden table surrounded by leather chairs, a leather sofa, and a bar area with stools.
A spacious living room with a brown leather sofa, a coffee table with a vase, and a mounted deer head on the wall.
A two-story building with a red roof and a flagpole with the American flag and a blue flag.

3. Dakota Prairie Lodge & Resort

Dakota Prairie Lodge & Resort
Pukwana
  • Rejuvenate at this rural lodge with deep-tissue spa treatments, rainfall showers, and a peaceful garden setting.
RM506
RM642 total
includes taxes & fees
9 Sept - 10 Sept
Dakota Prairie Lodge & Resort
A modern bathroom with a shower, two towels, a framed picture, and a vanity with a mirror.
A lobby with a reception desk, seating area, and a chandelier.
A modern indoor swimming pool with a clear blue water surface, surrounded by a stone wall and equipped with a changing area.
A modern bar area with leather chairs, a bar counter, and pendant lighting.

4. The Warrior Hotel, Autograph Collection

The Warrior Hotel, Autograph Collection
Sioux City
  • Rejuvenate at this elegant city centre hotel with a full-service spa and indoor pool for pure relaxation.
RM469
RM534 total
includes taxes & fees
20 Sept - 21 Sept
The Warrior Hotel, Autograph Collection
View all properties

Choose what matters most at spa hotels in Eastern South Dakota

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Eastern South Dakota Hotel Reviews

Hampton Inn Sioux Falls

Hampton Inn Sioux Falls

8/10 Good
"The hotel was newly remodeled. Beautiful. My only complaint was the breakfast. The waffles were great. The eggs were great. But the chicken sausages were nasty. Please bring back pork sausages."
Trevor 1-night trip
Posted less than an hour ago
Hampton Inn Sioux Falls
Clarion Pointe Sioux Falls Airport

Clarion Pointe Sioux Falls Airport

8/10 Good
"We got there late and left early the next morning. Everything seemed to be in working order. There was a foul odor in the hallway near the elevator but it was probably due to the trash can placed there. The staff were friendly and the continental breakfast was a standard hotel breakfast, nothing special. The room was clean and the bed was okay, not uncomfortable but not nearly as comfortable as the bed we slept in at the next hotel we stayed in on the following night."
Jerry 1-night trip
Posted 4 hours ago
Clarion Pointe Sioux Falls Airport
Thunderbird Lodge

Thunderbird Lodge

10/10 Excellent
"Clean room, Great Price"
Brian 1-night trip
Posted 19 hours ago
Thunderbird Lodge
Days Inn by Wyndham Mitchell SD

Days Inn by Wyndham Mitchell SD

10/10 Excellent
"Hot is out of order!! Slide was great to have"
Jared 3-night trip
Posted 1 day ago
Days Inn by Wyndham Mitchell SD

Explore a world of travel with Expedia