𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 East Cape Girardeau from RM274 (2026) - Fully Refundable Options

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Our top choices for East Cape Girardeau hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

RM408

RM461 total

includes taxes & fees

8 Oct - 9 Oct

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

RM429

RM488 total

includes taxes & fees

18 Oct - 19 Oct

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

3. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

RM413

RM466 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

4. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

RM380

RM429 total

includes taxes & fees

8 Oct - 9 Oct

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A spacious living room with a sofa set, a coffee table, and a dining area.

5. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

RM511

RM579 total

includes taxes & fees

12 Oct - 13 Oct

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

An outdoor patio with stone walls, wicker furniture, and large windows.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

6. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

RM432

RM487 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

7. The Riverview

Cape Girardeau

Alyssa

RM467

RM527 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

8. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Elizabeth

RM294

RM332 total

includes taxes & fees

11 Oct - 12 Oct

A modern retail area with a display of local items and snacks.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

9. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

RM365

RM416 total

includes taxes & fees

11 Oct - 12 Oct

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

An outdoor patio with tables and chairs, a stone wall, and large windows.

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

RM326

RM353 total

includes taxes & fees

2 Nov - 3 Nov

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

A hotel room with a bed, a TV, a desk, and a chair.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

11. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

RM358

RM426 total

includes taxes & fees

4 Oct - 5 Oct

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

12. Quality Inn Cape Girardeau North

Cape Girardeau

Danny

RM243

RM274 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

13. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

RM309

RM334 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A bathroom with a marble wall and a white bathtub.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

14. Town House Inn Cape Giradreau

Cape Girardeau

Joshua

RM286

RM334 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A hotel room with two beds, a brick wall, and a wooden headboard.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

15. Drury Inn & Suites Jackson MO

Jackson

Thomas

RM327

RM345 total

includes taxes & fees

7 Oct - 8 Oct

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

16. Town House Inn

Jackson

Taylor

RM291

RM315 total

includes taxes & fees

4 Oct - 5 Oct

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Top East Cape Girardeau Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

8/10 Good

"I usually stay here if I need to because I travel back and forth from northern IL and I usually have a lot of food to take home to southern MS. The full size fridge and freezer is very nice to have available and you don’t have to book a super fancy room to get one. Housekeeping can be hard work, but missing a rather large blood stain on the wall behind the door is disturbing. Thankfully I always travel with Lysol wipes and cleaned it up."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"EVERYONE was EXTREMELY FRIENDLY even maintenance all FRIENDLY"

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Clean rooms. Nice breakfast. Very nice staff."

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Town House Inn Cape Giradreau

8/10 Good

"The outside needed cleaning, but the room was very clean and well maintained."

More cheap stays in East Cape Girardeau

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

RM243

RM274 total

1 Nov - 2 Nov

includes taxes & fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

RM294

RM332 total

11 Oct - 12 Oct

includes taxes & fees

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

RM365

RM416 total

11 Oct - 12 Oct

includes taxes & fees

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

RM358

RM426 total

4 Oct - 5 Oct

includes taxes & fees

8/10 Very good! (1,001 reviews)

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

RM429

RM488 total

18 Oct - 19 Oct

includes taxes & fees

Hotel 7 Inn Anna

100 Richview Dr Anna IL

Get rates

6.6/10 (244 reviews)

Frequently asked questions

What's the best place to stay in East Cape Girardeau?

Located 4.6 mi (7.5 km) from the heart of East Cape Girardeau, Drury Plaza Hotel Cape Girardeau Conference Center is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Pear Tree Inn Cape Girardeau West and The Riverview. See all available top hotels, or vacation rentals in East Cape Girardeau.

If I need to cancel my hotel reservation in East Cape Girardeau, will I receive a refund?

Yes, most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in East Cape Girardeau.

What's it like to stay in East Cape Girardeau?

Travellers to East Cape Girardeau will find plenty to explore and enjoy. There are 111 hotels and other accommodation options in the surrounding area. Find out more about East Cape Girardeau.

What should I do while I'm visiting East Cape Girardeau?

Places to visit in the wider area include Century Casino & Hotel Cape Girardeau, Hunter Valley Winery and eDen Spa & Salon. You'll also find Show Me Center and Cape Splash Family Aquatic Center in the area. Take a look at what more there is to see and do in Expedia's East Cape Girardeau guide.

What's the weather like in East Cape Girardeau?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Cape Girardeau is 1491 mm.

East Cape Girardeau hotels from RM274

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in East Cape Girardeau

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for East Cape Girardeau hotels

1. Drury Plaza Hotel Cape Girardeau Conference Center

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3. Fairfield Inn & Suites by Marriott Cape Girardeau

4. Drury Inn & Suites Cape Girardeau

5. Courtyard by Marriott Cape Girardeau Downtown

6. Hampton Inn Cape Girardeau I 55 East

7. The Riverview

8. Pear Tree Inn Cape Girardeau West

9. Tru By Hilton Cape Girardeau

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

11. Candlewood Suites Cape Girardeau by IHG

12. Quality Inn Cape Girardeau North

13. Comfort Suites Jackson-Cape Girardeau

14. Town House Inn Cape Giradreau

15. Drury Inn & Suites Jackson MO

16. Town House Inn

Top East Cape Girardeau Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

Drury Inn & Suites Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Courtyard by Marriott Cape Girardeau Downtown

Town House Inn Cape Giradreau

More cheap stays in East Cape Girardeau

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Tru By Hilton Cape Girardeau

Candlewood Suites Cape Girardeau by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel 7 Inn Anna

Frequently asked questions

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