A historic stone fortress with a central dome and surrounding walls.

Best Luxury Hotels in Colon

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Colon Luxury Hotels

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Our top choices for Colon luxury hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a dining area, a TV, and a city view.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
  • Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
RM577
RM635 total
includes taxes & fees
27 Oct - 28 Oct
Hotel Riu Plaza Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.

2. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
RM1,414
RM1,556 total
includes taxes & fees
21 Oct - 22 Oct
Sofitel Legend Casco Viejo, Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
A pool with a central water feature, surrounded by seating areas and potted plants.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
RM1,252
RM1,377 total
includes taxes & fees
6 Nov - 7 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A hotel with a pool, beach, and palm trees.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.

4. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
  • Oceanfront luxury beckons with private beach, indulgent spa services, and refined dining at this beachfront Panama retreat.
RM841
RM925 total
includes taxes & fees
5 Nov - 6 Nov
The Westin Playa Bonita Panama
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A formal dining area with round tables, white tablecloths, and blue lace borders.
A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.
A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.

5. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
  • Spectacular waterfront luxury at Panama Canal hotel with premium dining and dual pools.
RM345
RM380 total
includes taxes & fees
7 Nov - 8 Nov
Radisson Hotel Panama Canal
A poolside area with lounge chairs and a view of the ocean.
A terrace with seating and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

6. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
RM1,172
RM1,289 total
includes taxes & fees
6 Nov - 7 Nov
JW Marriott Panama
A buffet with various food items including fruits, juices, and cheeses.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.
A gym with treadmills, weight machines, and dumbbells.

7. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
RM413
RM454 total
includes taxes & fees
30 Oct - 31 Oct
Courtyard by Marriott Panama Metromall
A restaurant with multiple dining tables, chairs, and a central water feature.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.
A historic building with ornate stonework and a balcony with plants.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

8. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
RM1,072
RM1,179 total
includes taxes & fees
21 Oct - 22 Oct
Hotel La Compañía Casco Antiguo
A rooftop pool with lounge chairs and a city skyline view.
A woman sitting on a bed in a hotel room with a city view.
A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.
A person seated on a wicker chair with a view of a cityscape through large windows.

9. Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Bella Vista
RM335
RM481 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Dann Carlton Marinn Place Panama Financial District
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop pool area with purple lounge chairs and a city skyline in the background.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.

10. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
  • Experience luxury and elegance in a Panamanian retreat with 2 restaurants, a spa, and casino.
RM652
RM717 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
View all properties

Top Colon Hotel Reviews

Hotel Ojos del Rio

Hotel Ojos del Rio

8/10 Good
"The room was clean,staff was friendly and helpful,the breakfast was super and the staff was remarkable and very polite and helpful Only thing the room didn't have a microwave or coffee maker that would of been a plus"
CHRIS 2-night trip
Posted 1 hour ago
Hotel Ojos del Rio
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Room was always Clean Friendly Staff Great Hotel"
Jermaine Jarrod 7-night trip
Posted 4 hours ago
Hotel Riu Plaza Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

8/10 Good
"Food was limited, but I enjoyed our stay ..3"
Mechalia 4-night trip
Posted 1 day ago
Decapolis Hotel Panama City

Frequently asked questions

Are you looking for a luxury hotel for your Colon holiday?
Use Expedia to arrange your flight to Panama City (PAC-Marcos A. Gelabert Intl.) airport or Balboa (BLB-Panama Pacifico Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Colon offers. Colon has some interesting things to see and do including Colon 2000 and Colon Free Zone, so you might want to take in the local sights during your visit.
What's the best luxury place to stay in Colon?
Sand Diamond Hotel is a luxury hotel with ski-in/ski-out access and a casino, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Colon?
Planning for the weather is an important factor for making your trip to Colon a success, especially when you're splurging. The hottest months are usually May and September, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Colon are November, July, August and October, with each month seeing an average of 350 mm of rainfall.
What's there to see and do in Colon?
Take in the sights and attractions that Colon offers with a visit to Colon 2000, Colon Free Zone and Gamboa Rainforest Resort. If you have extra time while you're in the area, you might want to see Fantastic Casino | Colón 2000 and Fort San Lorenzo.
How can I get around Colon?
It's easier to get around town in style when you know your options. If you want to venture outside the area, hop aboard a train at Colon Atlantic Passenger Station.