𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Cherokee from RM269 (2026) - Fully Refundable Options

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Our top choices for Cherokee hotels

A reception area with a wooden counter, a seating area with a chair and a sofa, and a trash bin.

A bathroom with a wooden vanity, a white sink, a mirror, and a towel rack.

A hotel entrance with a prominent 'HOTEL' sign, a covered entrance area, and a stone facade.

A hotel room with two beds, a TV, and a sliding door to the outside.

1. Heritage PLACE HOTEL IUKA

Iuka

Samantha

RM322

RM351 total

includes taxes & fees

27 Oct - 28 Oct

A spacious interior with a central staircase, a chandelier, and a view to the outdoors.

A modern dining area with wooden tables and benches, green chairs, and pendant lighting.

A spacious conference room with a high ceiling, large windows, and a grey carpet.

2. Spark by Hilton Tuscumbia Muscle Shoals

Tuscumbia

Patrick

RM340

RM378 total

includes taxes & fees

11 Nov - 12 Nov

A hotel room with a bed, a desk, a chair, a mirror, a painting, and a nightstand with a lamp.

A kitchen with blue tiles, a coffee machine, and a sink.

A restaurant with booths and tables, a counter with a blue tiled backsplash, and a door in the background.

A reception area with a reception desk, a blue sofa, and a coffee station.

3. Days Inn by Wyndham Muscle Shoals Florence

Muscle Shoals

Keith

RM291

RM323 total

includes taxes & fees

27 Oct - 28 Oct

A spacious lobby with a blue sofa, a wooden table, and chairs. There is a TV on a stand and a painting on the wall.

A hotel room with a bed, a desk, a television, a sofa, and a window with curtains.

A snack bar with refrigerated drinks, shelves stocked with snacks, and a wall sign advertising treats.

A reception area with a 'Welcome to the Honey Bee State' sign, a Hilton Honors sign, and a 'Team Members' sign.

4. Hampton Inn & Suites Florence-Downtown

Florence

Bruce

RM444

RM510 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a bed, a desk with chairs, a small kitchenette, and a TV.

A living room with a sofa, two stools, a small table, and a kitchenette area.

A Microtel Inn & Suites building with a parking lot and a sign indicating the hotel name.

A hotel reception area with a green sofa, a wooden reception desk, and a television on a cabinet.

5. Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Tuscumbia

Brian

RM257

RM285 total

includes taxes & fees

9 Nov - 10 Nov

A hotel room with a bed, a desk with a lamp, a TV, a sofa, and a view of greenery outside.

A spacious dining area with multiple tables and chairs, an air conditioning unit, and a large window providing a view of the outdoors.

A hotel lobby with a blue sofa, red chairs, a wooden cabinet with a TV, and a large wooden door.

A modern bathroom with a freestanding bathtub, a blue chair, and a wooden bench.

6. Comfort Inn & Suites Tuscumbia - Muscle Shoals

Tuscumbia

David

RM425

RM472 total

includes taxes & fees

4 Nov - 5 Nov

A bedroom with a brick wall, a dark blue headboard, and patterned pillows.

The Stricklin Hotel with a sign for Big Bad Breakfast.

A modern kitchen with dark blue cabinets, a white countertop, and a wooden floor.

A restaurant with a large aircraft model mural on the wall, wooden tables, and chairs.

7. The Stricklin Hotel

Florence

Dana

RM625

RM722 total

includes taxes & fees

27 Oct - 28 Oct

A hotel lobby with a seating area, a reception desk, and a check-in counter.

A fire pit surrounded by stone, with outdoor furniture and a pool in the background.

A hotel room with a bed, a TV, a desk with a chair, a coffee maker, and a map on the wall.

A modern hotel lobby with a bar area, seating arrangements, and a fireplace.

8. Residence Inn Florence Marriott

East Florence

Nathan

RM478

RM550 total

includes taxes & fees

8 Nov - 9 Nov

A modern hotel room with a large bed, a separate sitting area, a bathtub, and a view of the outdoors.

A spacious dining area with a Red Roof Inn sign, wooden flooring, and modern furniture.

A laundromat with washers and dryers, and a vending machine stocked with snacks and drinks.

A reception area with a dark wood reception desk, a red sign indicating free Wi-Fi, and two red leather chairs.

9. Red Roof Inn Muscle Shoals

Muscle Shoals

Keith

RM245

RM272 total

includes taxes & fees

27 Oct - 28 Oct

A spacious lobby with seating areas, a reception desk, and large windows.

A spacious indoor area with large windows, seating arrangements, and a flat-screen TV mounted on the wall.

A spacious lobby with a reception desk, seating area, and large windows.

A gym with treadmills, elliptical machines, and free weights.

10. Clarion Inn Sheffield Muscle Shoals

Sheffield

Billy

RM294

RM331 total

includes taxes & fees

3 Nov - 4 Nov

A spacious lounge with a fireplace, leather sofas, and a bar area.

A spacious bedroom with a large bed, a chandelier, and a stone wall.

A coffee shop with a large sign reading "COFFEE" and a smaller sign below stating "HOT SHAVES! CLEAN HANDS! ALWAYS FRESH!".

A bedroom with a bed, a standing lamp, a bookshelf, and a television.

11. GunRunner Boutique Hotel

Florence

John M

RM841

RM971 total

includes taxes & fees

2 Nov - 3 Nov

A hotel with a large pool area, a water tower, and a dome structure.

A hotel with a swimming pool, lounge chairs, and a waterfall feature.

A spacious living area with large windows, a central coffee table, sofas, and armchairs.

A restaurant with a curved layout, large windows offering a view of a body of water, and a bar area with a view.

12. Renaissance Shoals Resort & Spa

East Florence

Christina

RM1,099

RM1,264 total

includes taxes & fees

23 Nov - 24 Nov

A spacious lobby with a reception desk, seating area, and a balcony.

A Best Western Plus hotel with a covered entrance, multiple floors, and a parking lot.

A hotel room with a teal accent wall, a sofa, a wooden coffee table, a bed with white linens, and two bedside lamps.

A hotel room with a bed, a sofa, a coffee table, and two lamps.

13. Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Tuscumbia

Luke

RM423

RM463 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel room with a large bed, a desk, a chair, a window with a view, and a wall-mounted lamp.

A snack bar with shelves of snacks and a refrigerator with beverages.

A gym with cardio machines, weight benches, and a wall-mounted medicine ball rack.

A Hampton Inn hotel with a modern design, featuring a spacious entrance and a well-lit facade.

14. Hampton Inn Florence Midtown near University of North Alabama

Florence

calvin

RM533

RM613 total

includes taxes & fees

8 Nov - 9 Nov

A modern kitchen with wooden cabinets, a countertop with various appliances, and a view of the outdoors.

A reception area with two wooden reception desks, a blue rug, and a modern interior design.

A hotel room with two beds, a wooden headboard, a wall-mounted light fixture, and a framed picture.

A Holiday Inn Express & Suites hotel with a prominent entrance, multiple flags, and a landscaped area with a fountain.

15. Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Florence

Melissa

RM429

RM493 total

includes taxes & fees

8 Nov - 9 Nov

An indoor swimming pool with tiled steps and a sunlit room with chairs and a window.

A hotel room with a blue sofa, a bed with a red blanket, a desk with a lamp, and two framed pictures on the wall.

A hotel lobby with a reception desk, seating area with sofas and armchairs, and a patterned carpet.

A hotel lobby with a reception desk, a clock, and a sign for 'Comfort Suites'.

16. Comfort Suites Florence Shoals Area

Florence

Elizabeth

RM347

RM399 total

includes taxes & fees

15 Nov - 16 Nov

A reception area with a reception desk, a seating area with chairs and a table, a plant, a lamp, a bulletin board, and a window with a view of the outside.

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A kitchen with white cabinets, a black countertop, and a window with striped valance.

A courtyard with a central stone table and four benches, surrounded by a two-story building with balconies and large windows.

17. Keywest Inn - Tuscumbia/Muscle Shoals

Tuscumbia

Barbara

RM306

RM340 total

includes taxes & fees

27 Oct - 28 Oct

A blue mat with the text "Baymont Inn & Suites" on a wooden floor.

A hotel room with a large bed, bedside lamps, a desk, and a chair.

A row of white motel buildings with blue doors, a Baymont sign, and a parking lot.

A dining area with a long table and chairs, a kitchen area with appliances, and a sign on the wall.

18. Baymont by Wyndham Florence/Muscle Shoals

Florence

Alan

RM278

RM319 total

includes taxes & fees

15 Nov - 16 Nov

A reception area with a counter, a television, and a door labeled "EMPLOYEES ONLY".

A hotel room with two beds, a television mounted on the wall, and a window with blinds.

A building with a 'OPEN' sign, a door, windows, and a stone facade.

A modern bathroom with a marble wall, a bathtub, and a shower area.

19. Budget Inn & Suites

East Florence

Nazul

RM242

RM269 total

includes taxes & fees

28 Oct - 29 Oct

A modern living room with a wooden wall, a round table with stools, a sofa, a TV, and wall-mounted deer antlers.

A hotel with multiple rooms, a covered parking area, and a gravel ground.

A covered outdoor seating area with chairs and tables, a gravel floor, and a building with a metal exterior.

A room with two beds, wooden walls, a window, a nightstand, and framed pictures.

20. Pickwick Lake Lodge

Counce

Susan

RM588

RM675 total

includes taxes & fees

8 Nov - 9 Nov

View all properties

Compare top hotels in Cherokee

Heritage PLACE HOTEL IUKA Iuka View	Spark by Hilton Tuscumbia Muscle Shoals Tuscumbia View	Days Inn by Wyndham Muscle Shoals Florence Muscle Shoals View	Hampton Inn & Suites Florence-Downtown Florence View	Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals Tuscumbia View
9.0 Wonderful 217 reviews	8.8 Excellent 821 reviews	8.8 Excellent 1,002 reviews	9.2 Wonderful 749 reviews	8.2 Very good 1,001 reviews
RM322 RM351 total includes taxes & fees 27 Oct - 28 Oct	RM340 RM378 total includes taxes & fees 11 Nov - 12 Nov	RM291 RM323 total includes taxes & fees 27 Oct - 28 Oct	RM444 RM510 total includes taxes & fees 22 Nov - 23 Nov	RM257 RM285 total includes taxes & fees 9 Nov - 10 Nov

Save an average of 15% on thousands of hotels when you're signed in

Top Cherokee Hotel Reviews

Spark by Hilton Tuscumbia Muscle Shoals

8/10 Good

"Great newly renovated place to rest. We didn't have breakfast at the hotel so I can't speak on that but the coffee was decent."

Comfort Suites Florence Shoals Area

10/10 Excellent

"The rooms were very clean and the beds were comfortable. Parking was great. The staff was nice and always helpful. There was plenty of options on the breakfast buffet. This hotel was equal to the higher priced hotels i usually stay at. I will add this Hotel to my list of Hotel to stay at."

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

8/10 Good

"Fine hotel for the purpose. Our room smelled pretty heavily of musty dog."

The Stricklin Hotel

10/10 Excellent

"Love this hotel. It’s my go to when I go to Florence. Lovely people who operate the hotel. Cool hotel. Walking distance to food shopping. Wine bars. And Big Bad Breakfast is a must! ❤️❤️❤️"

Heritage PLACE HOTEL IUKA

10/10 Excellent

"The property and rooms are very well maintained and clean. The staff is awesome."

Hampton Inn & Suites Florence-Downtown

10/10 Excellent

"Quiet, spacious Rooms, large walk-in shower, and a much better than expected breakfast."

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

10/10 Excellent

"Room showed a few minor signs of wear and tear, but was clean and reasonably spacious. Breakfast was fine. Staff was excellent and friendly. Not too far from the major attractions and downtown Florence."

GunRunner Boutique Hotel

10/10 Excellent

"Great place ."

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

8/10 Good

"Hotel was great for the price. Comfortable bed. Main complaint is the carpet, in the rooms and common areas. It needs to be replaced as it is very worn."

More cheap stays in Cherokee

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

1852 Highway 72 E Tuscumbia AL

RM257

RM285 total

9 Nov - 10 Nov

includes taxes & fees

Days Inn by Wyndham Muscle Shoals Florence

2701 Woodward Ave Muscle Shoals AL

RM291

RM323 total

27 Oct - 28 Oct

includes taxes & fees

Clarion Inn Sheffield Muscle Shoals

4900 Hatch Blvd Sheffield AL

RM294

RM331 total

3 Nov - 4 Nov

includes taxes & fees

7.2/10 Good! (1,006 reviews)

Heritage PLACE HOTEL IUKA

1409 HERITAGE DRIVE IUKA MISS, 38852 Iuka MS

RM322

RM351 total

27 Oct - 28 Oct

includes taxes & fees

9/10 Wonderful! (217 reviews)

Comfort Suites Florence Shoals Area

140 Matthew Paul Ct Florence AL

RM347

RM399 total

15 Nov - 16 Nov

includes taxes & fees

8.8/10 Excellent! (881 reviews)

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

180 Etta Gray Street Florence AL

RM429

RM493 total

8 Nov - 9 Nov

includes taxes & fees

9/10 Wonderful! (653 reviews)

Frequently asked questions

What's the best place to stay in Cherokee?

Located 17 mi (27.4 km) from the heart of Cherokee, The Stricklin Hotel is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are Days Inn by Wyndham Muscle Shoals Florence and Renaissance Shoals Resort & Spa. See all available top hotels, or vacation rentals in Cherokee.

If I need to cancel my hotel reservation in Cherokee, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Cherokee.

What are some hotels with pools in Cherokee?

Renaissance Shoals Resort & Spa: Features an indoor pool, an outdoor pool and 2 restaurants. Comfort Suites Florence Shoals Area and Spark by Hilton Tuscumbia Muscle Shoals are a couple of other choices with an on-site pool. View all hotels with pools in Cherokee.

How is it to stay in Cherokee?

Travellers to Cherokee will find plenty to explore and enjoy. In Cherokee, there are 14 hotels and other accommodation options to choose from. Find out more about Cherokee.

What should I do while I'm visiting Cherokee?

The picturesque setting of Pickwick Lake and Tennessee River exemplify the area's natural beauty. You'll also find Cane Creek Canyon Nature Preserve and Ivy Green in the area. Take a look at what more there is to see and do in Expedia's Cherokee guide.

What's the seasonal weather in Cherokee?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 7°C. Average annual precipitation for Cherokee is 1589 mm.

Cherokee hotels from RM269

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Cherokee

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Cherokee hotels

1. Heritage PLACE HOTEL IUKA

2. Spark by Hilton Tuscumbia Muscle Shoals

3. Days Inn by Wyndham Muscle Shoals Florence

4. Hampton Inn & Suites Florence-Downtown

5. Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

6. Comfort Inn & Suites Tuscumbia - Muscle Shoals

7. The Stricklin Hotel

8. Residence Inn Florence Marriott

9. Red Roof Inn Muscle Shoals

10. Clarion Inn Sheffield Muscle Shoals

11. GunRunner Boutique Hotel

12. Renaissance Shoals Resort & Spa

13. Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

14. Hampton Inn Florence Midtown near University of North Alabama

15. Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

16. Comfort Suites Florence Shoals Area

17. Keywest Inn - Tuscumbia/Muscle Shoals

18. Baymont by Wyndham Florence/Muscle Shoals

19. Budget Inn & Suites

20. Pickwick Lake Lodge

Compare top hotels in Cherokee

Heritage PLACE HOTEL IUKA

Spark by Hilton Tuscumbia Muscle Shoals

Days Inn by Wyndham Muscle Shoals Florence

Hampton Inn & Suites Florence-Downtown

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Top Cherokee Hotel Reviews

Spark by Hilton Tuscumbia Muscle Shoals

Comfort Suites Florence Shoals Area

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

The Stricklin Hotel

Heritage PLACE HOTEL IUKA

Hampton Inn & Suites Florence-Downtown

Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

GunRunner Boutique Hotel

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

More cheap stays in Cherokee

Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Days Inn by Wyndham Muscle Shoals Florence

Clarion Inn Sheffield Muscle Shoals

Heritage PLACE HOTEL IUKA

Comfort Suites Florence Shoals Area

Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Frequently asked questions

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