What is Central Southwest like?

You'll be sure to have fun exploring Houston's Central Southwest neighbourhood. Make sure that you visit Wildcat Golf Club and Houston Sports Park as part of your Central Southwest travel plans.

What's a favourite hotel to stay in Central Southwest?

Expedia customers rank Cute And Cozy Hostel the highest for a stay in Central Southwest. Another favourite option in the neighbourhood is Crystal Suites .

How many hotels will I find in Central Southwest?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 74 Central Southwest hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Central Southwest, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals in Central Southwest.

What can I see and do in this Houston neighbourhood?

Spend some time exploring the natural setting of Central Southwest with a visit to Houston Sports Park and Eclectic Menagerie Park. Wildcat Golf Club and Aveva Stadium are also a couple of places to visit in the neighbourhood. A few places to visit in the area around Central Southwest include American Cowboy Museum, The Collective: Grand Ballroom and Garibaldi Sport Arena. When you're sightseeing around the area, Reliant Stadium and NRG Arena are a couple of other sights to visit.

Top 10 Central Southwest Hotels of 2026

A cityscape with a prominent modern skyscraper, historic buildings, and a well-maintained park with a jogging path.

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Our top choices for Central Southwest hotels

A modern hotel room with a large bed, wooden flooring, a bedside telephone, and a mirror.

1. Blue Diamond Inn

Central Southwest

George

RM366 total

includes taxes & fees

17 Oct - 18 Oct

A modern bedroom with a bed, a TV mounted on the wall, a door, and an air conditioning unit.

2. Crystal Suites

Central Southwest

Theresa

RM311 total

includes taxes & fees

17 Oct - 18 Oct

A neatly made bed with white linens, a wooden headboard, and a bedside table with a telephone.

3. Maxim III Motel

Central Southwest

Ebony

RM252 total

includes taxes & fees

8 Nov - 9 Nov

A kitchen with a built-in espresso machine, a microwave, and a wine cooler.

4. Sweet Home - Private BR in a Shared Home

Central Southwest

RM1,709 total

includes taxes & fees

11 Oct - 12 Oct

A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

5. Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

6.1 km from Central Southwest

Elisa

RM528 total

includes taxes & fees

11 Oct - 12 Oct

A reception area with a wooden reception desk, two refrigerators, and clocks displaying different city names.

6. Best Western Plus Pearland/Houston Medical Center Hotel

Southeast Houston, 8.4 km from Central Southwest

AYTUNC

RM469 total

includes taxes & fees

12 Oct - 13 Oct

A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

7. Hyatt Place Houston Medical Center

Texas Medical Center, 8 km from Central Southwest

Anthony

RM611 total

includes taxes & fees

26 Oct - 27 Oct

A hotel room with a large bathtub, a bed with white bedding, a wooden headboard, and a nightstand with a lamp.

8. Comfort Suites Houston near Medical Center- NRG Stadium

6.8 km from Central Southwest

Tamy

RM383 total

includes taxes & fees

4 Nov - 5 Nov

A bar area with a long counter, bar stools, a refrigerated display case with beverages, and a menu board above the counter.

9. Courtyard By Marriott Houston Medical Center Reliant Park

7.6 km from Central Southwest

Jorge

RM583 total

includes taxes & fees

11 Oct - 12 Oct

10. Hyatt House Houston Medical Center

Texas Medical Center, 8 km from Central Southwest

Debra

RM607 total

includes taxes & fees

26 Oct - 27 Oct

A multi-level hotel lobby with a central seating area, multiple floors, and a staircase.

11. Houston Marriott South at Hobby Airport

Southeast Houston, 17.3 km from Central Southwest

valerie

RM538 total

includes taxes & fees

10 Oct - 11 Oct

A spacious room with large windows, a red armchair, a small table, and a cabinet with decorative items.

12. Studio 6 Houston, TX – Pearland/Medical Center

Southeast Houston, 12.1 km from Central Southwest

Mariesha

RM287 total

includes taxes & fees

12 Oct - 13 Oct

A hotel lobby with a seating area, a reception desk, and a staircase.

13. Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham

16.4 km from Central Southwest

Dearmar

RM396 total

includes taxes & fees

12 Oct - 13 Oct

A hotel entrance with a covered walkway, a 'No Parking' sign, and a 'Home 2 Suites by Hilton' sign.

14. Home2 Suites by Hilton at the Galleria

Greater Uptown, 11.7 km from Central Southwest

Alexis

RM506 total

includes taxes & fees

15 Oct - 16 Oct

A modern breakfast area with labeled sections for yogurt, eggs, and milk, and a sign indicating the direction to the restrooms.

15. Holiday Inn Express & Suites Stafford NW - Sugar Land by IHG

14.4 km from Central Southwest

Jessica Monica

RM414 total

includes taxes & fees

18 Oct - 19 Oct

A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

16. Hilton Houston Plaza/Medical Center

Texas Medical Center, 9.3 km from Central Southwest

Marvin

RM529 total

includes taxes & fees

15 Oct - 16 Oct

An outdoor patio with round tables and chairs, a brick wall, and a view of a body of water and trees at dusk.

17. Hyatt Place Houston/Sugar Land

18.8 km from Central Southwest

Daniel

RM515 total

includes taxes & fees

13 Oct - 14 Oct

A rooftop pool area with lounge chairs and a view of a tall building at night.

18. The Westin Houston Medical Center/Museum District

Texas Medical Center, 9.3 km from Central Southwest

Matthew

RM818 total

includes taxes & fees

25 Oct - 26 Oct

An indoor dining area with tables and chairs, a central fountain, and a stone wall with a lion sculpture.

19. Doubletree by Hilton Houston Hobby Airport

Southeast Houston, 16.2 km from Central Southwest

Amelia

RM468 total

includes taxes & fees

22 Oct - 23 Oct

A modern hotel room with a large bed, bedside tables, a desk, and a chair.

20. Best Western Plus Sugar Land/Stafford

16.8 km from Central Southwest

Henry

RM393 total

includes taxes & fees

20 Oct - 21 Oct

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Where to stay in Central Southwest

Find the best Central Southwest areas for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

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A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

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A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

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A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

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A modern cityscape with a tram and tall buildings.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

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Top Central Southwest Hotel Reviews

Hotel Zaza Houston Museum District

8/10 Good

"Nice property. Convenient shuttle to locations W/in 3 miles. Cons: 1. air handlers in room are quite loud; 2. tv remote only had one battery. repeated calls to several depts yielded only busy signals, front desk clerk clueless. promised engineer never showed. After dinner calls still yielded busy signals…no one picked up in any of four departments. another visit to front desk finally yielded, after 20 min. wait, an engineer with new remote."

Cambria Hotel Houston Downtown Convention Center

10/10 Excellent

"A perfect stay. The room was incredibly spacious, beautiful and modern. The bathroom was also excellent. Great value for money. Incredible staff, who were extremely accommodating and friendly. The bar and restaurant area was beautiful. If I’m back in Houston I’ll definitely be staying here."

Great Wolf Lodge Webster

8/10 Good

"Clean rooms and beds, awesome choices of restaurants and snack areas, felt safe. I gave 4 starts because I believe everything there was incredible, but, they don't have much celebration options for "couples" who may be there for anniversary or celebration together. The place is diverse for both adults and children. We loved it. Only wish there was more celebratory for anniversaries/couples."

The Westin Houston Medical Center/Museum District

10/10 Excellent

"This was a great choice for our long weekend trip to Houston. It is in a convenient location near the Museum District and Rice Village and while it is near several hospitals we didn’t find it to be too noisy. Definitely avail yourself of the light rail if headed to the museums or the beautiful Hermann Park. Rideshare trips can take a bit long to arrive due to all of the traffic lights so plan for that if you aren’t driving. The restaurant and bar also offer a pleasant atmosphere but are not open for late-night dining or drinks."

The Chifley Houston, Tapestry Collection by Hilton

8/10 Good

"Mostly great stay! Easy and friendly check in, large and comfortable rooms...very nice to have a suite. Cold AC, comfy beds. A few tiny snags....no one answered at guest services when I called, unsure if this was a no one at the desk issue or a phone issue? I called from my cell and got someone. Room service is to go (man, I really miss proper room service!) and just ok, my coffee was cold and no butter for my toast. I don't mind paying extra for room service, but I'd love to receive everything really hot and presented well. Overall, I would definitely recommend this property....pricing was very reasonable for uptown Houston too!"

Hotels in Central Southwest, Houston

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Our top choices for Central Southwest hotels

1. Blue Diamond Inn

2. Crystal Suites

3. Maxim III Motel

4. Sweet Home - Private BR in a Shared Home

5. Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

6. Best Western Plus Pearland/Houston Medical Center Hotel

7. Hyatt Place Houston Medical Center

8. Comfort Suites Houston near Medical Center- NRG Stadium

9. Courtyard By Marriott Houston Medical Center Reliant Park

10. Hyatt House Houston Medical Center

11. Houston Marriott South at Hobby Airport

12. Studio 6 Houston, TX – Pearland/Medical Center

13. Heritage Inn Suites Houston/Sugar Land, Trademark by Wyndham

14. Home2 Suites by Hilton at the Galleria

15. Holiday Inn Express & Suites Stafford NW - Sugar Land by IHG

16. Hilton Houston Plaza/Medical Center

17. Hyatt Place Houston/Sugar Land

18. The Westin Houston Medical Center/Museum District

19. Doubletree by Hilton Houston Hobby Airport

20. Best Western Plus Sugar Land/Stafford

Where to stay in Central Southwest

Downtown Houston

The Galleria

Texas Medical Center

Montrose

Houston Central Business District

Top Central Southwest Hotel Reviews

Hotel Zaza Houston Museum District

Frequently asked questions

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