A large white dome building with a red brick base, surrounded by green trees and a clear blue sky.

Best Luxury Hotels in Central Missouri

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Check availability on Central Missouri Luxury Hotels

Tonight
12 Sept - 13 Sept
Tomorrow
13 Sept - 14 Sept
Next weekend
18 Sept - 20 Sept
In two weeks
25 Sept - 27 Sept

Our top choices for Central Missouri luxury hotels

A modern bar area with a long counter, bar stools, and a view of the city through large windows.
A hotel with a modern design, featuring a prominent entrance and a large sign.
A hotel room with two beds, a television, a desk with a telephone, and a mirror.
A spacious living room with a fireplace, comfortable seating, and a large window offering a view of the outside.

1. DoubleTree by Hilton Hotel Jefferson City

DoubleTree by Hilton Hotel Jefferson City
Jefferson City
RM514
RM590 total
includes taxes & fees
20 Sept - 21 Sept
DoubleTree by Hilton Hotel Jefferson City
A modern hotel lobby with a large TV screen, a reception desk, and a decorative plant display.
A luxurious hotel lobby with a large TV screen, a blue sofa, and a chandelier.
A theater with a marquee reading "TIGER" and a sign for "The Tiger Hotel."
A grand lobby with a large TV screen, a chandelier, and a blue sofa.

2. voco The Tiger Hotel Columbia, MO by IHG

voco The Tiger Hotel Columbia, MO by IHG
Columbia
  • Historic charm meets modern luxury in Columbia's heart with pillowtop beds, 24-hour service, and immaculate spaces.
RM655
RM810 total
includes taxes & fees
20 Sept - 21 Sept
voco The Tiger Hotel Columbia, MO by IHG
An aerial view of a marina at dusk with illuminated buildings, docks, and boats.
A marina with docks and a large hotel building in the background.
A group of people dining at an outdoor table with a view of a body of water and city lights in the background.
A poolside area with stone walls and a bar.

3. Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
Lake Ozark
  • Lakeside spa resort offers luxury treatments and poolside cocktails for a serene escape.
RM351
RM534 total
includes taxes & fees
5 Oct - 6 Oct
Camden on the Lake Resort & Spa
A lakeside bar named "FIRE ICE" with outdoor seating and a view of the lake.
An outdoor seating area with a fire pit, chairs, and a view of a lake at sunset.
A lobby with a stone fireplace, seating area, and a view of the sky through the ceiling.
A spacious lobby with a high ceiling, stone accents, and a central fireplace.

4. Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa
Lake Ozark
  • Lakeside retreat features spa treatments, 36 holes of championship golf, and Japanese gardens.
RM339
RM464 total
includes taxes & fees
11 Oct - 12 Oct
Lodge Of Four Seasons Golf Resort, Marina & Spa
A spacious bar area with high tables and chairs, a large flat-screen TV mounted on the wall, and a bar stocked with bottles.
A hotel room with two beds, a large window with curtains, and a carpeted floor.
A modern bar area with a long counter, bar stools, and a fireplace.
A hotel room with a sofa, a green ottoman, a desk with a lamp, and a framed cityscape picture on the wall.

5. Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East
Columbia
RM383
RM432 total
includes taxes & fees
27 Sept - 28 Sept
Drury Plaza Hotel Columbia East
An outdoor seating area with tables and chairs, a bar, and a fire pit.
A modern restaurant with a bar area, red leather chairs, and a large mural on the wall.
A sign for The Broadway hotel, a Doubletree by Hilton, with a water feature in front.
A multi-story hotel with a prominent entrance, a covered area, and a clear sky at dusk.

6. The Broadway Columbia - a DoubleTree by Hilton

The Broadway Columbia - a DoubleTree by Hilton
Columbia
RM617
RM701 total
includes taxes & fees
4 Oct - 5 Oct
The Broadway Columbia - a DoubleTree by Hilton
A hot tub, a fire pit, and a view of a lake.
A bathroom with a bathtub, a shower, and a vanity with a mirror.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.
A row of houses with a driveway leading to a gated entrance.

7. Hermann Hill

Hermann Hill
Hermann
RM1,432
RM1,646 total
includes taxes & fees
16 Sept - 17 Sept
Hermann Hill
A lakeside gazebo with outdoor seating and a view of the lake.
A rustic cabin with a covered porch and a garden area.
A bedroom with a bed, a wooden bench, a TV, and a sliding glass door to the outside.
A cozy cabin interior with a stone fireplace, wooden walls, and a high ceiling.

8. Walnut Waters Bed & Breakfast

Walnut Waters Bed & Breakfast
Lone Jack
RM1,298
RM1,395 total
includes taxes & fees
11 Oct - 12 Oct
Walnut Waters Bed & Breakfast
A red brick house with a stone foundation, a curved driveway, and a well-maintained lawn.
A swimming pool with a red border, surrounded by lounge chairs and tables, set against a backdrop of trees and a distant view.
A modern, enclosed spa room with a glass partition, a control panel, and a green-lit floor.
A bathroom with a white vanity, a large mirror, two wall-mounted lights, and a glass shower enclosure.

9. Up Up and Away Lodging

Up Up and Away Lodging
Hermann
RM1,077
RM1,154 total
includes taxes & fees
14 Sept - 15 Sept
Up Up and Away Lodging
A compact living space with a sofa, a TV, a kitchen area with a fridge, microwave, and coffee maker, and a dining table.
A black building with large windows, a covered porch with a flag, and potted plants.
A compact kitchen with a marble backsplash, a refrigerator, a washing machine, and a dining area with chairs.
A modern kitchen with a wooden island, bar stools, and a flat-screen TV.

10. The Mercantile on the Katy Trail

The Mercantile on the Katy Trail
Hermann
  • Newly renovated Victorian retreat offers golf, garden sanctuary, and luxury suites on the Katy Trail.
RM779
RM837 total
includes taxes & fees
15 Sept - 16 Sept
The Mercantile on the Katy Trail
View all properties

Top Central Missouri Hotel Reviews

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

10/10 Excellent
"a lot nicer than I thought it would be. Good beds"
Jackie 1-night trip
Posted 1 hour ago
Baymont by Wyndham Columbia, MO
Capitol Plaza Hotel Jefferson City

Capitol Plaza Hotel Jefferson City

8/10 Good
"Our tv didn’t work and parking was $10, which is weird since we’re staying at their hotel. But room was clean and beds were very comfortable. I would stay again."
Donna 2-night trip
Posted 7 hours ago
Capitol Plaza Hotel Jefferson City
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

10/10 Excellent
"Property was clean staff was very helpful. Great restaurants and pools!"
Tony 2-night trip
Posted 1 day ago
Margaritaville Lake Resort Lake of the Ozarks

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