Cairo hotels from RM234
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20 Sept - 21 SeptTomorrow
21 Sept - 22 SeptNext weekend
25 Sept - 27 SeptIn two weeks
2 Oct - 4 OctOur top choices for Cairo hotels
1. Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
Santiago
RM289
RM321 total
includes taxes & fees
2 Oct - 3 Oct
2. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
William
RM243
RM270 total
includes taxes & fees
21 Sept - 22 Sept
3. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
Jay
RM271
RM301 total
includes taxes & fees
23 Sept - 24 Sept
4. Eagle Inn Charleston
Eagle Inn CharlestonCharleston
Jackson
RM314
RM349 total
includes taxes & fees
21 Sept - 22 Sept
5. La Center Motel
La Center MotelLa Center
Carrie
RM198
RM234 total
includes taxes & fees
1 Oct - 2 Oct
6. Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near PaducahCunningham
RM608
RM1,186 total
includes taxes & fees
28 Sept - 29 Sept
Stay near popular Cairo attractions
Fort Defiance State Park
7.4/10 (15 reviews)
Where the mighty Mississippi and Ohio rivers converge, Fort Defiance Park offers a rare view of this natural phenomenon. Explore the historic grounds where Lewis and Clark once trained the Corps of Discovery in 1803.
Learn more about Cairo
At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artefacts from this once-thriving river port town.
See all hotels in Cairo
Top Cairo Hotel Reviews
The Riverstone Hotel Charleston-Sikeston
8/10 Good
"Overall it was excellant, other then the toilet running constantly... Pool could have been cleaner, considering the heat-wave they were having............."
Quality Inn Cairo I-57
8/10 Good
"Good service,nice stuff and no complaints"
La Center Motel
10/10 Excellent
"Great AC unit in the room!"
Eagle Inn Charleston
10/10 Excellent
"Great"
More cheap stays in Cairo
La Center Motel
474 W Kentucky Dr La Center KY
RM198
RM234 total
1 Oct - 2 Oct
includes taxes & fees
7.6/10 Good! (22 reviews)
Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
RM243
RM270 total
21 Sept - 22 Sept
includes taxes & fees
6.8/10 (668 reviews)
The Riverstone Hotel Charleston-Sikeston
102 Drake St Charleston MO
RM271
RM301 total
23 Sept - 24 Sept
includes taxes & fees
6.8/10 (434 reviews)
Quality Inn Cairo I-57
13201 Kessler Road Cairo IL
RM289
RM321 total
2 Oct - 3 Oct
includes taxes & fees
6.4/10 (295 reviews)
Eagle Inn Charleston
2811 East Marshall Street Charleston MO
RM314
RM349 total
21 Sept - 22 Sept
includes taxes & fees
6.6/10 (107 reviews)
