𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Byron from RM273 (2026) - Fully Refundable Options

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Our top choices for Byron hotels

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

A spacious living room with a stone fireplace, blue sofas, and a flat-screen TV.

A spacious lobby with a central seating area, a reception desk, and a fireplace.

A modern dining area with wooden tables and chairs, a kitchen with granite countertops, and a view of the outdoors through large windows.

1. Comfort Inn & Suites West - Medical Center

Rochester

yuan

RM363

RM418 total

includes taxes & fees

10 Oct - 11 Oct

A hotel reception desk with a wooden counter, a computer, and a vase with flowers.

A living room with stone walls, a fireplace, leather furniture, and a ceiling fan.

A hotel room with a large bed, a view through a sliding glass door to an outdoor area, a nightstand with a lamp, and a wooden headboard.

An indoor swimming pool with wooden beams and white chairs around it.

2. Baymont by Wyndham Kasson Rochester Area

Kasson

Lynnette

RM271

RM291 total

includes taxes & fees

4 Oct - 5 Oct

A modern dining area with high tables, chairs, and pendant lighting.

A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

A swimming pool with a tiled deck, sun loungers, and a lifeguard chair.

3. Hampton Inn & Suites Rochester-North

Rochester

Dr. Tim

RM419

RM482 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a reception desk, sofas, and a coffee table.

A hotel room with a large bed, a sofa, a TV, and a desk.

An indoor swimming pool with clear blue water, surrounded by tiled flooring and equipped with a pool ladder.

A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

4. Sleep Inn & Suites West-Near Medical Center

Rochester

Jacqueline

RM367

RM423 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

An outdoor patio area with stone walls, outdoor seating, and landscaped gardens.

A compact hotel room with a kitchenette, a dining area, a seating area with a sofa and armchairs, and a large window with curtains.

A multi-story Staybridge Suites building with a stone facade and multiple windows.

5. Staybridge Suites Rochester - Commerce Dr NW by IHG

Rochester

MATTHEW

RM535

RM616 total

includes taxes & fees

24 Oct - 25 Oct

An indoor swimming pool with a dolphin sculpture, wooden ceiling, and clear windows.

A hotel room with a large bed, two bedside tables with lamps, a telephone, and a window with sheer curtains.

A hotel reception area with a red 'Hello' sign, a reception desk, a coffee station, and a fireplace.

A hotel room with a flat-screen TV, a sofa with a red pillow, a small table, and a lamp.

6. TownePlace Suites by Marriott Rochester

Rochester

Terry

RM400

RM460 total

includes taxes & fees

4 Oct - 5 Oct

A Holiday Inn Express building with a covered entrance, outdoor seating area, and a well-lit facade.

A coffee station with two espresso machines and a variety of coffee pods and cups.

A hotel dining area with multiple tables and chairs, a coffee station, and a seating area with sofas.

7. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Kutzky Park

Janet

RM449

RM517 total

includes taxes & fees

2 Oct - 3 Oct

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

8. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

Jon

RM492

RM566 total

includes taxes & fees

3 Oct - 4 Oct

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern lounge area with a sofa, chairs, and tables.

A modern restaurant with a counter, seating area, and a TV screen.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

9. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

Vickie

RM499

RM575 total

includes taxes & fees

3 Oct - 4 Oct

An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.

A hotel room with a kitchen area, a bed, a TV, and a seating area.

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A modern kitchen with black cabinets, white countertops, and a tiled backsplash. There are pendant lights, a refrigerator, and a coffee machine.

10. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Rochester

Vicky

RM403

RM464 total

includes taxes & fees

1 Oct - 2 Oct

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A reception area with a reception desk, two armchairs, a clock, and a framed artwork on the wall.

A compact hotel room with a kitchenette, a dining area, a sofa, and a bed.

A Microtel Inn & Suites building with a signboard, a parking lot, and a clear sky.

11. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Rochester

Richard

RM284

RM327 total

includes taxes & fees

28 Sept - 29 Sept

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern indoor pool area with lounge chairs and a pool.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

12. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

Kathy

RM482

RM555 total

includes taxes & fees

2 Oct - 3 Oct

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

13. Hampton Inn Rochester-South

Rochester

dennis

RM432

RM497 total

includes taxes & fees

4 Oct - 5 Oct

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

14. Residence Inn by Marriott Rochester Mayo Clinic Area South

Rochester

Chee

RM539

RM621 total

includes taxes & fees

2 Oct - 3 Oct

A lobby with leather chairs, a reception desk, a TV, and a coffee station.

A restaurant with tables and chairs, a trash bin, a coffee machine, and a television displaying a sports game.

A hotel with a modern building featuring a prominent sign, a covered entrance, and a parking area.

15. Aspen Select

Kutzky Park

Sue

RM526

RM636 total

includes taxes & fees

16 Oct - 17 Oct

An indoor swimming pool with clear water, wooden flooring, and a ceiling with wooden beams and lights.

A gym with treadmills, an elliptical, and a water station.

A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.

A room with a TV mounted on the wall, a wooden table, and two patterned armchairs.

16. Med City Inn & Suites - Mayo Clinic Area

Kutzky Park

Jose

RM291

RM335 total

includes taxes & fees

26 Sept - 27 Sept

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A restaurant interior with wooden tables, chairs, and a stone wall.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

17. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest

Carrie

RM440

RM507 total

includes taxes & fees

2 Oct - 3 Oct

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

18. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park

MATTHEW

RM501

RM576 total

includes taxes & fees

3 Oct - 4 Oct

A spacious living area with a wooden dining table, bar stools, and a patterned armchair. A staircase leads to an upper level with a balcony.

An indoor swimming pool with a wooden ceiling and large windows.

A spacious lobby with a high ceiling, a central seating area with patterned sofas and ottomans, a reception desk, and a staircase leading to an upper level.

19. Quality Inn near Medical Center

Rochester

Lerry

RM257

RM295 total

includes taxes & fees

19 Oct - 20 Oct

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

A hotel lobby with striped armchairs, a sofa, a fireplace, and a clock on the wall.

A hotel entrance with a prominent Aspen sign, a large brick building in the background, and a clear sky.

20. Aspen Suites

Rochester

Dana

RM579

RM700 total

includes taxes & fees

27 Sept - 28 Sept

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Stay near popular Byron attractions

Oxbow Park

8.8/10 (5 reviews)

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the cosy cafes or top-notch restaurants in this walkable area.

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Community Center Park

Community Center Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.

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Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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High Point Shopping Center

You can do some window-shopping at High Point Shopping Center during your trip to Byron. Amble around the area's parks or experience its art scene.

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Zollman Zoo

Visit the native and exotic animals who call Zollman Zoo home during your travels in Byron. Amble around the area's parks or experience its art scene.

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Salem Town Hall

After visiting Salem Town Hall, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Top Byron Hotel Reviews

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"This place will be my cozy retreat whenever I’m in Rochester. I had such a wonderful time during my 9-day visit! Jenni and Johnny (aka Johnny Cash) were incredibly kind and always ready to lend a hand. When navigating health issues a friendly face and helpful staff and feeling as though you matter changes everything. Breakfast items changed everyday and were tasty, but my favorite part had to be the evening soup Mon - Thu at 5:30p while supplies last. LOL"

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Love this place!"

Kahler Inn and Suites - Mayo Clinic Area

8/10 Good

"Room was clean"

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"I will always stay here when I am visiting my childhood home. It is just very comfortable!! Like coming home... thanks to all the staff! Sincerely, Jim Reardon"

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Great breakfast"

Aspen Select

10/10 Excellent

"Very convenient to Saint Mary's hospital"

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent

"We enjoyed our stay. The breakfast was wonderful. We were disappointed the hot tub only ran for the first evening though and was down for maintenance after. And the exercise room was a bit grimy"

Hampton Inn Rochester-South

10/10 Excellent

"Clean room and hotel. Breakfast was great"

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent

"Was there for a surgery at the Mayo and they were so helpful and accommodating. Very grateful for the facility and the staff"

More cheap stays in Byron

Birch Hill Suite Rochester – Med City

3595 Commercial Drive SW Rochester MN

RM237

RM273 total

4 Oct - 5 Oct

includes taxes & fees

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

RM291

RM335 total

26 Sept - 27 Sept

includes taxes & fees

Comfort Inn & Suites Rochester South Mayo Clinic

7320 Airport View Dr Sw Rochester MN

RM316

RM364 total

25 Oct - 26 Oct

includes taxes & fees

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

RM383

RM440 total

2 Oct - 3 Oct

includes taxes & fees

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE Rochester MN

RM392

RM451 total

4 Oct - 5 Oct

includes taxes & fees

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN

RM403

RM464 total

1 Oct - 2 Oct

includes taxes & fees

8.2/10 Very good! (1,000 reviews)

Frequently asked questions

Where is the best place to stay in Byron?

Located 9.3 mi (14.9 km) from the heart of Byron, AmericInn by Wyndham Rochester Near Mayo Clinic is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in Byron.

If I need to cancel my hotel reservation in Byron, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Byron.

How is it to stay in Byron?

Visitors can enjoy all that Byron has to offer, including the zoo, golf courses and bars. Tourists can also enjoy the city's parks and art. In Byron, there are 3 hotels and other accommodation options to choose from. Find out more about Byron.

What should I see while I'm in Byron?

Favourite places to visit include Oxbow Park, Links of Byron Mini Golf and Cheery Meadows Center. A couple of additional sights to add to your itinerary are High Point Shopping Center and Byron Town Square. Take a look at what more there is to see and do in Expedia's Byron guide.

What's the seasonal weather in Byron?

The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in Byron are January, March, April and February, with each month seeing an average of 19 cm of snowfall.

Byron hotels from RM273

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Byron

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Byron hotels

1. Comfort Inn & Suites West - Medical Center

2. Baymont by Wyndham Kasson Rochester Area

3. Hampton Inn & Suites Rochester-North

4. Sleep Inn & Suites West-Near Medical Center

5. Staybridge Suites Rochester - Commerce Dr NW by IHG

6. TownePlace Suites by Marriott Rochester

7. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

8. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

9. Home2 Suites by Hilton Rochester Mayo Clinic Area

10. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

11. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

12. Hyatt House Rochester/Mayo Clinic Area

13. Hampton Inn Rochester-South

14. Residence Inn by Marriott Rochester Mayo Clinic Area South

15. Aspen Select

16. Med City Inn & Suites - Mayo Clinic Area

17. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

18. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

19. Quality Inn near Medical Center

20. Aspen Suites

Stay near popular Byron attractions

Oxbow Park

Community Center Park

Putting Green

Somerby Park

East Brookfield Park

High Point Shopping Center

Zollman Zoo

Salem Town Hall

Top Byron Hotel Reviews

Hyatt House Rochester/Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kahler Inn and Suites - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Aspen Select

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Hampton Inn Rochester-South

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

More cheap stays in Byron

Birch Hill Suite Rochester – Med City

Med City Inn & Suites - Mayo Clinic Area

Comfort Inn & Suites Rochester South Mayo Clinic

Brentwood Inn & Suites

Holiday Inn Express Rochester South - Mayo Area by IHG

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Frequently asked questions

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