Top 10 Hotels Near Buffalo Museum of Science in Buffalo for 2026

A large mammoth skeleton in a museum with classical architecture.

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Our top choices for Buffalo Museum of Science hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A grand room with a chandelier, a fireplace, and ornate furniture.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

A room with a red patterned sofa, wooden bookshelves, a chandelier, and a traditional wooden coffee table.

1. InnBuffalo off Elmwood

Elmwood Village, 3 km from Buffalo Museum of Science

Terese

RM522

RM599 total

includes taxes & fees

9 Nov - 10 Nov

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A historic building with a prominent tower and a traditional brick facade.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A room with a textured ceiling, a chandelier, and walls painted in a two-tone color scheme.

2. Buffalo Harmony House

Allentown, 3.2 km from Buffalo Museum of Science

John

RM1,330

RM1,546 total

includes taxes & fees

22 Oct - 23 Oct

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A bedroom with a four-poster bed, a yellow sofa, a white coffee table, and a desk with a chair.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

3. The Edward Hotel

Elmwood Village, 2.4 km from Buffalo Museum of Science

Grace

RM527

RM725 total

includes taxes & fees

25 Oct - 26 Oct

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

4. The Mansion On Delaware Ave

Allentown, 3 km from Buffalo Museum of Science

Marilyn

RM805

RM923 total

includes taxes & fees

25 Oct - 26 Oct

A two-story building with a white exterior, a red door, and large windows.

A living room with a fireplace, a chandelier, leather sofas, and a glass coffee table.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

5. Buffalo Guesthouse

Allentown, 2.4 km from Buffalo Museum of Science

Jan

RM710

RM815 total

includes taxes & fees

22 Oct - 23 Oct

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.

6. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 1.9 km from Buffalo Museum of Science

Sara

RM643

RM751 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern gym with cardio machines, a mirrored wall, and a blue accent wall.

A modern kitchen with a central island, bar stools, and various appliances.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

7. Best Western on the Avenue

Allentown, 2.8 km from Buffalo Museum of Science

Alyson

RM621

RM725 total

includes taxes & fees

16 Nov - 17 Nov

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A Holiday Inn Express & Suites hotel with a brick facade, located at the intersection of Washington and Chippewa streets.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

A gym with exercise equipment, a mirror, and a television.

8. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 3.1 km from Buffalo Museum of Science

Sarah

RM482

RM562 total

includes taxes & fees

16 Nov - 17 Nov

A lobby with a staircase, seating area, and a view of the outdoors.

A reception area with a marble wall, a reception desk with glass panels, a clock, and a television mounted on the wall.

A hotel room with two beds, a desk, a television, and a window.

A hotel with a classic brick facade, a glass entrance, and flags.

9. Lenox Hotel and Suites

Allentown, 2.6 km from Buffalo Museum of Science

Thomas

RM446

RM512 total

includes taxes & fees

29 Oct - 30 Oct

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

A modern living room with a large window, a flat-screen TV, a sofa, a coffee table, and a patterned rug.

A modern cafe with round tables and chairs, a bar area, and a neon sign.

A modern hotel with a glass facade, multiple floors, and a prominent 'Aloft' sign.

10. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 3 km from Buffalo Museum of Science

Anthony T

RM813

RM949 total

includes taxes & fees

8 Nov - 9 Nov

A dining area with a wooden table set for four, surrounded by chairs. There is a kitchen area with cabinets and appliances in the background.

A kitchen with wooden cabinets, a dishwasher, and a dining area with a table and chairs.

A bedroom with a bed, bedside lamps, a nightstand, a window with curtains, and wall art.

A kitchen with wooden cabinets, stainless steel appliances, and a red toaster.

11. 4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.4 km from Buffalo Museum of Science

RM1,213

RM2,148 total

includes taxes & fees

22 Oct - 23 Oct

A buffet setup with various food items and utensils.

A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".

A hotel room with a sofa, a bed, a desk, and a chair. There are lamps on the desk and bedside tables.

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

12. Salvatores Grand Hotel

13.1 km from Buffalo Museum of Science

Mary

RM690

RM785 total

includes taxes & fees

22 Oct - 23 Oct

A modern hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a large mirror.

13. Hampton Inn Buffalo - Amherst, NY

10.6 km from Buffalo Museum of Science

Warren

RM517

RM588 total

includes taxes & fees

2 Nov - 3 Nov

A modern lounge area with sofas, round tables, and a stone accent wall.

A hotel with a brick facade, multiple balconies, and a sign for 'The Mosey Hotel & Residences'.

14. The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

9 km from Buffalo Museum of Science

Andres

RM691

RM786 total

includes taxes & fees

2 Nov - 3 Nov

A spacious lobby with high ceilings, a grand staircase, and a gift shop.

A hotel room with two beds, a desk, a chair, a coffee machine, and a large window with curtains.

A bar area with red upholstered bar stools, a bar counter, and a chandelier.

A multi-story hotel with a stone facade, a prominent entrance with a metal archway, and a parking lot in front.

15. The Delavan Hotel & Spa

12.4 km from Buffalo Museum of Science

Tiffany

RM474

RM539 total

includes taxes & fees

3 Nov - 4 Nov

A patio area with outdoor seating, a barbecue grill, and a stone wall.

A modern indoor space with a foosball table, seating areas, a mural, and a television screen.

A modern lounge area with seating, tables, and hanging chairs.

A modern hotel lobby with a central seating area, a reception desk, and a colorful mural.

16. Tru by Hilton Williamsville Buffalo Airport

13 km from Buffalo Museum of Science

Stephen P

RM482

RM549 total

includes taxes & fees

15 Nov - 16 Nov

A large indoor swimming pool with clear blue water, surrounded by lounge chairs and a sauna area.

A modern lounge area with blue upholstered chairs, a wooden rocking chair, a round table, and a patterned rug.

A hotel lobby with a seating area featuring sofas, ottomans, and tables. A reception desk and a bar are visible in the background.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

17. Hampton Inn Buffalo-Williamsville

9.6 km from Buffalo Museum of Science

Robert

RM656

RM746 total

includes taxes & fees

15 Nov - 16 Nov

A modern kitchen with a central island, wooden cabinets, and a bar area with stools.

A modern hotel with a flat roof, large windows, and a covered entrance.

A modern hotel lobby with a curved seating area, a flat-screen TV, and a dining area.

An outdoor patio with a round table, chairs, a cushioned seating area, and a barbecue grill.

18. Springhill Suites Buffalo Airport

13 km from Buffalo Museum of Science

Matthias

RM529

RM602 total

includes taxes & fees

8 Nov - 9 Nov

A parking lot with cars and a covered walkway.

A hotel room with a bed, a desk, a sofa, and a painting on the wall.

A Hyatt Place hotel with a modern facade, a well-lit entrance, and a parking lot.

19. Hyatt Place Buffalo/Amherst

8.3 km from Buffalo Museum of Science

Margie

RM588

RM669 total

includes taxes & fees

2 Nov - 3 Nov

A hotel room with a sofa, armchair, ottoman, desk, television, and a painting on the wall.

Two front-loading washing machines side by side in a laundry room.

A gym with treadmills, an elliptical, and a stationary bike, featuring a colorful wall mural.

A hotel room with a large bed, a desk with a chair, a television, a small table with a chair, and a painting on the wall.

20. Hilton Garden Inn Buffalo Airport

9.4 km from Buffalo Museum of Science

Mary

RM569

RM664 total

includes taxes & fees

15 Nov - 16 Nov

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Compare popular hotels close to Buffalo Museum of Science

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 225 reviews	View
Buffalo Harmony House	10.0 Exceptional 56 reviews	View
The Edward Hotel	9.6 Exceptional 268 reviews	View
The Mansion On Delaware Ave	9.4 Exceptional 1,001 reviews	View
Buffalo Guesthouse	9.4 Exceptional 223 reviews	View

Top Buffalo Museum of Science Hotel Reviews

Hyatt Regency Buffalo / Hotel and Conference Center

10/10 Excellent

"Very nice for an overnight"

The Richardson Hotel

10/10 Excellent

"The bar/wait person was terrific, engaging, helpful, obviously enjoying her occupation and employment at the Richardson. How refreshing to witness. Carefully refurbished historic property. If you are in the Buffalo area, this property is well worth your time and money."

Residence Inn by Marriott Buffalo Downtown

10/10 Excellent

"Very clean. Convenient location near many restaurants. Very quiet."

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

10/10 Excellent

"Great"

Best Western on the Avenue

10/10 Excellent

"Very pleasant stay, all of the staff was very helpful and friendly."

Curtiss Hotel, an Ascend Collection Hotel

10/10 Excellent

"From the moment you enter the Curtis’s hotel you feel relaxed; the staff care for your needs (had extra blankets within 10 minutes to our room and immediately made up the pull out couch for our daughter.). The hot springs is an oasis minutes from great restaurants."

The Mansion On Delaware Ave

10/10 Excellent

"My friend and I stayed at the Mansion for 10 days and it was a joy! The breakfasts are really gourmet and really kept us nourished until the late afternoon. The staff were very good natured and helpful. The room was comfortable and very clean. I heard no noise from inside the hotel though I was in a front-facing room and there was some street noise. The parking lot across the street was very convenient. Also, the location to restaurants is amazing. We walked quite a bit through the Elmwood neighborhood quite a bit and were routinely delighted in all the beautiful houses and hidden shops and bar/restaurants."

Hampton Inn & Suites Buffalo Downtown

10/10 Excellent

"The hotel & room were excellent! Beginning with the staff at the front desk, check in was easy & friendly. The room was beautiful, clean & spacious. Check out was easily completed online, no need to wait in line at the desk. Location was right downtown Buffalo. Beautiful buildings and a local pub right across the street."

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

You can find out about the history of Buffalo with a stop at Buffalo Central Terminal. Experience the entertainment choices and great live music in this vibrant area.

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Johnnie B. Wiley Sport Pavilion

Catch an event at Johnnie B. Wiley Sport Pavilion during your trip to Buffalo. Experience the area's entertainment choices and great live music.

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Paul Robeson Theater

Get tickets for a show at Paul Robeson Theater, a theatre with a story to tell in Buffalo. Experience the area's entertainment choices and great live music.

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African American Cultural Center

Enjoy a stop at African American Cultural Center, an entertaining place to visit in Buffalo. Experience the area's acclaimed theatre scene and great live music.

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Broadway Market

You can browse for the perfect souvenirs at Broadway Market during your visit to Buffalo. Experience the area's acclaimed theatre scene and great live music.

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Koessler Athletic Center

Catch an event at Koessler Athletic Center during your trip to Buffalo.

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Montante Cultural Center

Enjoy an outing to Montante Cultural Center during your stay in Buffalo.

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Hellenic Orthodox Church of the Annunciation

After visiting Hellenic Orthodox Church of the Annunciation, make a plan to see the other sights and activities in Buffalo.

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Frequently asked questions

What's the area like around Buffalo Museum of Science?

Buffalo Museum of Science is located in a historic area of Buffalo known for its great live music scene. If you're looking for a convenient place to stay, take a look at the 14 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Buffalo Museum of Science?

Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. It's located 1.2 mi (1.9 km) from Buffalo Museum of Science. Other good choices within 5 miles include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find close to Buffalo Museum of Science?

Expedia has 14 hotels and other accommodation options within a mile from Buffalo Museum of Science.

If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?

Yes, most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best deals near Buffalo Museum of Science.

What can I see and do near Buffalo Museum of Science?

Study the collections at Buffalo AKG Art Museum, Buffalo History Museum or Buffalo and Erie County Naval and Military Park. Some landmarks that you won't want to miss include Buffalo Central Terminal, Statler Tower and Richardson Olmsted Complex. You can watch performances at Kleinhans Music Hall, Town Ballroom and Road Less Traveled Productions if you're interested in local theatre.

Hotels near Buffalo Museum of Science

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Buffalo Museum of Science hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. The Mansion On Delaware Ave

5. Buffalo Guesthouse

6. Wyndham Garden Buffalo Downtown

7. Best Western on the Avenue

8. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

9. Lenox Hotel and Suites

10. Aloft by Marriott Buffalo Downtown

11. 4 Mi to Dtwn: Family Home in Buffalo

12. Salvatores Grand Hotel

13. Hampton Inn Buffalo - Amherst, NY

14. The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

15. The Delavan Hotel & Spa

16. Tru by Hilton Williamsville Buffalo Airport

17. Hampton Inn Buffalo-Williamsville

18. Springhill Suites Buffalo Airport

19. Hyatt Place Buffalo/Amherst

20. Hilton Garden Inn Buffalo Airport

Compare popular hotels close to Buffalo Museum of Science

Top Buffalo Museum of Science Hotel Reviews

Hyatt Regency Buffalo / Hotel and Conference Center

The Richardson Hotel

Residence Inn by Marriott Buffalo Downtown

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Best Western on the Avenue

Curtiss Hotel, an Ascend Collection Hotel

The Mansion On Delaware Ave

Hampton Inn & Suites Buffalo Downtown

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

Johnnie B. Wiley Sport Pavilion

Paul Robeson Theater

African American Cultural Center

Broadway Market

Koessler Athletic Center

Montante Cultural Center

Hellenic Orthodox Church of the Annunciation

Frequently asked questions