𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Anniston from RM266 (2026) - Fully Refundable Options

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Our top choices for Anniston hotels

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A reception area with a counter, a flat-screen TV, and a window with blinds.

A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

RM243

RM272 total

includes taxes & fees

13 Oct - 14 Oct

A building with a fountain and flower beds in front.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

2. The Riverstone Hotel Charleston-Sikeston

Charleston

Kathleen

RM272

RM304 total

includes taxes & fees

14 Oct - 15 Oct

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

3. Best Western Plus Sikeston I-55

Sikeston

Shelley

RM340

RM387 total

includes taxes & fees

15 Oct - 16 Oct

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

4. Drury Inn & Suites Sikeston, MO

Sikeston

Tim

RM384

RM441 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

5. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

RM396

RM451 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

6. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

RM284

RM324 total

includes taxes & fees

13 Oct - 14 Oct

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

7. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

RM413

RM469 total

includes taxes & fees

18 Oct - 19 Oct

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

8. Hampton Inn Sikeston

Sikeston

Lori

RM431

RM490 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

9. TownePlace Suites by Marriott Sikeston

Sikeston

Rubin

RM413

RM470 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

10. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

RM271

RM309 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A motel with a covered entrance, multiple rooms, and a parking lot.

11. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Marcia

RM233

RM266 total

includes taxes & fees

18 Oct - 19 Oct

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

12. Comfort Inn & Suites Sikeston I-55

Sikeston

Kathryn

RM343

RM390 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

13. Eagle Inn Charleston

Charleston

Jackson

RM270

RM302 total

includes taxes & fees

13 Oct - 14 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a counter, a coffee machine, and seating.

A bathroom with a bathtub, toilet, and shower curtain.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

14. Country Yard Inn and Suite

Sikeston

William

RM239

RM284 total

includes taxes & fees

13 Oct - 14 Oct

A hotel lobby with a reception desk, seating area, and a large window.

A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.

A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

15. Quality Inn Cairo I-57

Cairo

Santiago

RM282

RM313 total

includes taxes & fees

2 Nov - 3 Nov

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Top Anniston Hotel Reviews

Drury Inn & Suites Sikeston, MO

8/10 Good

"Clean comfortable room & the bathroom was HUGE. Breakfast was good. Good selection & everything tasted good."

Super 8 by Wyndham Sikeston/Miner Area

8/10 Good

"It is a clean place, and we enjoyed our stay"

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"Easy parking, our bathroom sink was leaning forward and we had to place our soap in the sink so it didn't slide on the floor."

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"Clean, comfortable room. Nice staff and good breakfast choices."

TownePlace Suites by Marriott Sikeston

10/10 Excellent

"My overall experience was amazing from the time I checked in until I left. The staff were super pleasant and incredible. My room was clean and spacious. I never been in an extended stay room before. I definitely will be booking a suite like this one again."

Quality Inn Cairo I-57

8/10 Good

"Good service,nice stuff and no complaints"

Eagle Inn Charleston

10/10 Excellent

"Great"

More cheap stays in Anniston

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

RM233

RM266 total

18 Oct - 19 Oct

includes taxes & fees

7/10 Good! (686 reviews)

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

RM243

RM272 total

13 Oct - 14 Oct

includes taxes & fees

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

RM271

RM309 total

1 Nov - 2 Nov

includes taxes & fees

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

RM340

RM387 total

15 Oct - 16 Oct

includes taxes & fees

8.4/10 Very good! (1,000 reviews)

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

RM396

RM451 total

8 Nov - 9 Nov

includes taxes & fees

8.8/10 Excellent! (517 reviews)

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

RM431

RM490 total

25 Oct - 26 Oct

includes taxes & fees

Frequently asked questions

Where is the best place for a stay in Anniston?

Drury Inn & Suites Sikeston, MO, located 12.5 mi (20.1 km) from the heart of Anniston, is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in Anniston.

If I need to cancel my hotel reservation in Anniston, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Anniston.

What is staying in Anniston like?

Travellers to Anniston will find plenty to explore and enjoy. There are 23 hotels and other accommodation options in the surrounding area. Find out more about Anniston.

What should I see while I'm in Anniston?

Places to visit in the wider area include Columbus-Belmont State Park, Big Oak Tree State Park and Fort Defiance State Park. You'll also find Central Park and Sikeston Depot Museum in the area. Take a look at what more there is to see and do in Expedia's Anniston guide.

What's the seasonal weather like in Anniston?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Anniston is 1518 mm.

Anniston hotels from RM266

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Anniston

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Anniston hotels

1. Super 8 by Wyndham Charleston/Sikeston East MO

2. The Riverstone Hotel Charleston-Sikeston

3. Best Western Plus Sikeston I-55

4. Drury Inn & Suites Sikeston, MO

5. Holiday Inn Express & Suites Sikeston Southwest by IHG

6. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

7. Fairfield Inn & Suites by Marriott Sikeston

8. Hampton Inn Sikeston

9. TownePlace Suites by Marriott Sikeston

10. Days Inn and Suites by Wyndham Sikeston

11. Super 8 by Wyndham Sikeston/Miner Area

12. Comfort Inn & Suites Sikeston I-55

13. Eagle Inn Charleston

14. Country Yard Inn and Suite

15. Quality Inn Cairo I-57

Top Anniston Hotel Reviews

Drury Inn & Suites Sikeston, MO

Super 8 by Wyndham Sikeston/Miner Area

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express & Suites Sikeston Southwest by IHG

TownePlace Suites by Marriott Sikeston

Quality Inn Cairo I-57

Eagle Inn Charleston

More cheap stays in Anniston

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Charleston/Sikeston East MO

Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn Sikeston

Frequently asked questions

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