Five Star Hotels in Florida Panhandle

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Check availability on Florida Panhandle 5 Star Hotels

Tonight
28 Dec - 29 Dec
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29 Dec - 30 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Our top choices for Florida Panhandle 5-star hotels

Exterior
The Henderson Beach Resort & Spa

The Henderson Beach Resort & Spa

The Henderson Beach Resort & Spa
5.0 star property
Crystal Beach
9.2 out of 10, Wonderful, (1003)
"Clean room, amenities were good. Beach access, bike rentals as well. "
United States
Joe
The price is RM1,211
RM1,593 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Henderson Beach Resort & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Panhandle.
The Pensacola Beach Resort

The Pensacola Beach Resort

165 Fort Pickens Road Pensacola Beach FL
The price is RM543 per night from 1 Jan to 2 Jan
RM543
RM622 total
1 Jan - 2 Jan 2026
includes taxes & fees
9.4/10 Exceptional! (2,683 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Panhandle

Escape to a little-seen corner of Florida for stunning white-sand beaches, charming fishing towns and cities rich with national history.

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Destin showing general coastal views, a sandy beach and a sunset

Top Florida Panhandle Hotel Reviews

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Stay in Luxury: 5 Star Hotels in Florida Panhandle

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Florida Panhandle trip. You'll join the multitudes of holidaymakers who have made Florida Panhandle so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Florida Panhandle and indulge in the finer things in life for a while.

5-Star Hotels in Florida Panhandle

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Florida Panhandle are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Florida Panhandle 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Florida Panhandle! Choose one of our Florida Panhandle 5-star hotels today and soothe yourself in luxe surroundings at your convenience.


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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Panhandle?
You'll find a variety of pricing options for 5-star hotels in Florida Panhandle on Expedia. How much you'll pay will depend on when you want to travel, length of stay and other factors. Compare all of the available accommodation for your chosen dates and use our pricing and other filters to discover the ideal upscale stay.

  • Search for the lowest price per night from RM370

What makes a hotel 5 stars in Florida Panhandle?
In Florida Panhandle, a hotel is required to offer a certain level of high-end conveniences to be rated 5 stars. These can include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their superior standard of service. You can expect things like in-room massages, concierge services and nightly turn-down services. Some may also offer thoughtful touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Florida Panhandle?
Find a luxurious escape that includes your lodging, meals, drinks and entertainment in Florida Panhandle with the help of Expedia's filters. Search for resorts rated 5 stars and click on the "All inclusive" filter. Double-check what's included in the price. That way, you can take full advantage of all the premium perks as soon as you arrive.

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