A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Four Star Hotels in Southern Indiana

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Check availability on Southern Indiana 4 Star Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Southern Indiana 4-star hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Judy
RM572
RM673 total
includes taxes & fees
8 Nov - 9 Nov
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.
A modern interior with a fireplace, bookshelves, and seating areas.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Kristan
RM830
RM976 total
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

3. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
John
RM585
RM688 total
includes taxes & fees
25 Oct - 26 Oct
The Brown Hotel
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A hotel dining area with long tables, booths, and a bar.

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Frances
RM532
RM626 total
includes taxes & fees
15 Nov - 16 Nov
Embassy Suites Louisville Downtown
A modern lobby with a curved metallic structure, a seating area with a sofa and a small table, and an escalator in the background.
A table set for a formal event with candles, floral centerpieces, and gold-toned candle holders.
A modern indoor swimming pool with clear glass walls, lounge chairs, and a wooden wall in the background.
A reception area with a wooden wall and a neon sign that reads "Sway LOCAL SOUTHERN EATERY".

5. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Michael Jered
RM727
RM855 total
includes taxes & fees
30 Oct - 31 Oct
Hyatt Regency Louisville
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A reception area with marble counters, modern pendant lighting, and potted orchids.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

6. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Ricardo
RM804
RM946 total
includes taxes & fees
8 Nov - 9 Nov
Louisville Marriott Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A steam fountain in a brick alleyway.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

7. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Matt
RM621
RM751 total
includes taxes & fees
15 Nov - 16 Nov
21c Museum Hotel Louisville
Bar (on property)
A brightly lit grocery store with yellow shelving and a central checkout counter.
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

8. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Tyler
RM551
RM648 total
includes taxes & fees
30 Oct - 31 Oct
Hotel Genevieve part of JdV by Hyatt
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A bar with shelves of liquor bottles and a bartender preparing drinks.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

9. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Heather
RM930
RM1,095 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Distil, Autograph Collection
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A modern restaurant interior with a staircase, round tables, and a brick wall.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

10. The Grady

The Grady
Downtown Louisville
United States
Donna
RM636
RM748 total
includes taxes & fees
15 Nov - 16 Nov
The Grady
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.
A modern hotel room with a large bed, a city view, and a unique headboard design.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Cameron
RM634
RM746 total
includes taxes & fees
9 Nov - 10 Nov
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern hotel entrance with a covered walkway, a parking area, and a building with multiple floors.
A fountain with multiple jets of water in front of a building with a curved facade and large windows.
A neatly made breakfast tray on a bed with a coffee pot, croissant, and fruit bowl.
A conference room with round tables, chairs, and a carpeted floor.

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
Downtown Evansville
United States
Aleli Rodriguez
RM413
RM475 total
includes taxes & fees
1 Nov - 2 Nov
DoubleTree by Hilton Evansville
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.
A spacious living room with a fireplace, wooden paneling, a television, and a blue sofa.
A bakery display with pastries and bread, a coffee station, and a Christmas tree in the background.
A grand staircase with ornate railings and a marble floor, leading to a high-ceilinged lobby with decorative moldings and a chandelier.

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Angel
RM635
RM747 total
includes taxes & fees
20 Nov - 21 Nov
Seelbach Hilton Louisville Downtown
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.

14. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Kevin
RM472
RM761 total
includes taxes & fees
26 Oct - 27 Oct
Stellar Suites
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.
A covered porch with a brick wall, a wooden door, and a hanging light fixture.
A marble countertop with a tray of colorful glassware, a bottle, and two glasses. A framed painting hangs above, and two lamps are on either side.
A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.

15. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
David
RM377
RM426 total
includes taxes & fees
26 Oct - 27 Oct
The Pepin Mansion Historic B&B
A modern lounge with leather sofas, a coffee table, and a view of a classical building.
A modern interior with a wooden dining table, leather sofas, and a bar area with shelves.
A building with a sign reading "Pursuit Spirits Co." and a large window display.
A narrow corridor with exposed brick walls, wooden flooring, and a seating area with tables and chairs.

16. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.
A modern living room with a dining area, a blue sofa, a ceiling fan, and a view of a balcony.
A modern kitchen with white cabinets, stainless steel appliances, and a dining area with a table and chairs.
A gym with exercise equipment, mirrors, and a TV screen.

17. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Jennifer
RM384
RM919 total
includes taxes & fees
25 Oct - 26 Oct
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.
In-room dining
Terrace/patio
Private kitchen

18. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
Canada
Darlene
RM608
RM687 total
includes taxes & fees
30 Oct - 31 Oct
stayAPT Suites Louisville North-Clarksville
A large, multi-story building with a prominent tower and multiple windows.
A spacious living area with a large, ornate rug, a wooden bench, and a staircase with white balusters.
A dining table set with placemats, folded napkins, cutlery, and a coffee cup.
A large outdoor swimming pool with a Ferris wheel in the background.

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.
A kitchen with wooden cabinets, a refrigerator, a coffee maker, and a tiled backsplash.
A kitchen with a black refrigerator, a dining area with a table and chairs, and a living room with a blue sofa.
A living room with a sofa, a coffee table, and a ceiling fan. There is a dining area with a table and chairs.

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.

See all hotels in Southern Indiana
A riverboat with multiple decks and passengers, docked near a bridge.

Top Southern Indiana Hotel Reviews

Find out more about Southern Indiana

Take Your Pick of 4 Star Hotels in Southern Indiana

The get-go of any holiday starts with choosing a great spot. Southern Indiana has been a popular destination with guests because it offers so much to do and see. But, "location, location, location" applies to more than just what city where your plane lands. Now that you have a feel for the town, it's time you to get to know your new digs.

Accommodations as Picturesque as Southern Indiana

Search Expedia.com.sg for the right 4 Star Southern Indiana Hotel to suit your fancy. Plenty of these people wrote tips to help you select the accommodation that is the right fit for your holiday.You'll be more than glad to get back to your resort every night. Southern Indiana has dozens of good options in the 4-star hotel range that create the ideal getaway.

A stay at one of these lodgings ensure that whether you are just relaxing after a day of checking out Southern Indiana or you are ready to lie down for the night, you'll be as comfortable as possible. You won't go without a thing during your stay at one of these accommodations. Visitors have consistently given them high marks for their attentive service. It's no surprise that loads of guests recommend it.

Reserve a 4-Star Hotel in Southern Indiana Today!

Your trip to Southern Indiana should be one that you'll reminisce over for years to come, and booking a 4-star hotel will help create memories that are incredible. Make sure to make a reservation soon. With so few hotels, and plenty of people desiring to vacation in Southern Indiana, you may miss out on your perfect hotel.

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.
  • Search for the lowest price from RM426
What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

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