Hotels near Mississippi River

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (358 reviews)
"Excellent stay !!! Quite "
United States
Bradley
The price is RM324
RM368 total
includes taxes & fees
16 Jan - 17 Jan
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (20 reviews)
"It was very clean and very nice place to stay, has a very home and cozy feeling walking into the room."
United States
Bryan
The price is RM387
RM440 total
includes taxes & fees
18 Jan - 19 Jan
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (737 reviews)
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is RM237
RM274 total
includes taxes & fees
18 Jan - 19 Jan
Baymont by Wyndham Hannibal

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"Very run down and trash around the property, but the room was clean and comfortable for our one night stop. Convenience of the location"
United States
Natalie
The price is RM251
RM296 total
includes taxes & fees
11 Feb - 12 Feb
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (513 reviews)
"The room was dirty so dirty we left didn't spend the night there, and the smell in the building weed or something else not sure which, it was ridiculous so we went to Hannibal and stayed at the Days inn "
United States
paul
The price is RM243
RM276 total
includes taxes & fees
16 Jan - 17 Jan
Economy Inn Wentzville

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (165 reviews)
"Great place to stay!"
United States
Sandy
The price is RM576
RM801 total
includes taxes & fees
16 Jan - 17 Jan
Riverside Inn Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,001 reviews)
"Pool was perfect"
United States
Jennifer
The price is RM409
RM470 total
includes taxes & fees
20 Jan - 21 Jan
Best Western On The River

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.6 out of 10, (1,002 reviews)
"Great place to stay "
United States
Askar
The price is RM255
RM293 total
includes taxes & fees
16 Jan - 17 Jan
Relax Inn Saint Charles

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,000 reviews)
"Room was excellent and clean"
United States
catherine
The price is RM234
RM269 total
includes taxes & fees
18 Jan - 19 Jan
Days Inn by Wyndham St Peters/St Charles

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Clean rooms quiet and really nice place "
United States
Vic
The price is RM375
RM435 total
includes taxes & fees
8 Feb - 9 Feb
Sleep Inn & Suites Hannibal West

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,000 reviews)
"Staff was great "
United States
Courtney
The price is RM248
RM303 total
includes taxes & fees
18 Jan - 19 Jan
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

Extended Stay America Select Suites St Louis Earth City

Extended Stay America Select Suites St Louis Earth City
2.5 star property
107.1 km from Mississippi River
6.6 out of 10, (883 reviews)
"Nothing bad to say about this Hotel. Great, clean rooms and awesome staff."
United States
Charles
The price is RM281
RM339 total
includes taxes & fees
23 Jan - 24 Jan
Extended Stay America Select Suites St Louis Earth City

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (495 reviews)
"I had to pay for my family to swim in the pool. The poll area was hazardous because there was drywall pealing off from the ceiling and around the pool. "
United States
Clarence and Kari
The price is RM215
RM241 total
includes taxes & fees
18 Jan - 19 Jan
Baymont by Wyndham Keokuk

Super 8 by Wyndham Bowling Green

Super 8 by Wyndham Bowling Green
2.0 star property
23.9 km from Mississippi River
8.4 out of 10, Very good, (487 reviews)
"Front desk people,...both evening 25th and morning 26th were very pleasant and helpful."
United States
Leroy
Super 8 by Wyndham Bowling Green

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.4 out of 10, (33 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is RM273
RM309 total
includes taxes & fees
10 Feb - 11 Feb
LAKEVIEWINN

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (24 reviews)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is RM641
RM736 total
includes taxes & fees
17 Jan - 18 Jan
Lighthouse Inn & Suites

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
103.4 km from Mississippi River
5.8 out of 10, (1,000 reviews)
"The best thing is the wonderful beds and pillows totally comfortable comfortable. Also television preferences is great for people that want to relax."
United States
Kathy
The price is RM241
RM279 total
includes taxes & fees
18 Jan - 19 Jan
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (669 reviews)
"Room was spacious and very clean. Bed comfortable. Breakfast was great! Staff friendly and helpful. "
United States
Judy
The price is RM308
RM366 total
includes taxes & fees
25 Jan - 26 Jan
Comfort Inn & Suites - Hannibal

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
"Overall, very nice stay"
United States
Cary
The price is RM235
RM270 total
includes taxes & fees
19 Jan - 20 Jan
Motel 6 Hannibal, MO

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (519 reviews)
"It was ok"
United States
Mike
The price is RM276
RM318 total
includes taxes & fees
5 Feb - 6 Feb
Sleep Inn Saint Charles North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Hampton Inn St. Louis-Downtown (At the Gateway Arch) and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.