Bridge over Mississippi River, New Orleans in background

Hotels near Mississippi River

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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (366 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
United States
Brent
The price is RM325
RM369 total
includes taxes & fees
15 Jun - 16 Jun
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (25 reviews)
"Very nice place to stay loved the brick walls and wood floors leading up to the rooms"
United States
Gary
The price is RM431
RM489 total
includes taxes & fees
22 Jun - 23 Jun
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (774 reviews)
"The staff were very friendly and helpful, The breakfast was probably the best we had experienced at any hotel where we have stayed. If we pass through the area again, we will likely choose to stay there again."
United States
Carol
The price is RM256
RM297 total
includes taxes & fees
15 Jun - 16 Jun
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,014 reviews)
"Clean rooms, decent breakfast"
United States
Christina
The price is RM448
RM517 total
includes taxes & fees
28 Jun - 29 Jun
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (178 reviews)
"Surprisingly fun property, clean, quiet (except for the train whistles). Hot tub was a great addition! Close to downtown fun! Would stay here again!"
United States
Michael
The price is RM728
RM980 total
includes taxes & fees
16 Jun - 17 Jun
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Good breakfast"
United States
Neah
The price is RM497
RM579 total
includes taxes & fees
28 Jun - 29 Jun
Sleep Inn & Suites Hannibal West

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (546 reviews)
"Room was clean but basic"
United States
James
The price is RM284
RM322 total
includes taxes & fees
15 Jun - 16 Jun
Economy Inn Wentzville

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
9.0 out of 10, Wonderful, (30 reviews)
"Fun themed rooms."
United States
Kelly
The price is RM693
RM940 total
includes taxes & fees
15 Jun - 16 Jun
Lighthouse Inn & Suites

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.8 out of 10, (52 reviews)
"The staff is very friendly and the hotel is very clean and decently priced plus they are dog friendly"
United States
David
The price is RM274
RM309 total
includes taxes & fees
21 Jun - 22 Jun
LAKEVIEWINN

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,010 reviews)
"Nice staff, good parking, clean room."
United States
Susan
The price is RM219
RM253 total
includes taxes & fees
21 Jun - 22 Jun
Motel 6 Hannibal, MO

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (704 reviews)
"As always the beds at comfort inn are so comfortable. Enjoyed our stay."
United States
Tracey
The price is RM351
RM417 total
includes taxes & fees
12 Jul - 13 Jul
Comfort Inn & Suites - Hannibal

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,004 reviews)
"Great spot"
United States
Jeremy
The price is RM276
RM317 total
includes taxes & fees
21 Jun - 22 Jun
Days Inn by Wyndham St Peters/St Charles

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (519 reviews)
"Easy to find a access. Clean rooms."
United States
Charles
The price is RM299
RM335 total
includes taxes & fees
21 Jun - 22 Jun
Baymont by Wyndham Keokuk

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,011 reviews)
"Parking was easy and safe, when the staff was available, they were courteous, and breakfast was good."
United States
Dan
The price is RM303
RM352 total
includes taxes & fees
12 Jul - 13 Jul
Quality Inn & Suites Hannibal West

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,003 reviews)
"Property was clean and staff was friendly."
United States
Etta
The price is RM270
RM311 total
includes taxes & fees
25 Jun - 26 Jun
Super 8 by Wyndham Hannibal

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,012 reviews)
"Great stay"
United States
Micaela
The price is RM286
RM350 total
includes taxes & fees
5 Jul - 6 Jul
La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (168 reviews)
"The room was clean . The staff was helpful on things to do in the area. It was a very relaxing and the town was beautiful"
United States
Samantha
The price is RM251
RM291 total
includes taxes & fees
21 Jun - 22 Jun
Howard Johnson BY Wyndham Hannibal

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (541 reviews)
"I enjoy my fligth"
United States
Eulogio
The price is RM318
RM365 total
includes taxes & fees
5 Jul - 6 Jul
Sleep Inn Saint Charles North

Extended Stay America Select Suites St Louis Earth City

Extended Stay America Select Suites St Louis Earth City
2.5 star property
107.1 km from Mississippi River
6.6 out of 10, (911 reviews)
"Not a bad place"
United States
Robert
The price is RM365
RM437 total
includes taxes & fees
15 Jun - 16 Jun
Extended Stay America Select Suites St Louis Earth City

Motel 6 Maryland Heights, MO

Motel 6 Maryland Heights, MO
2.0 star property
111 km from Mississippi River
6.2 out of 10, (1,008 reviews)
"Stay was ok, room wasn't the best but was clean and staff helpful"
United States
Bradley
The price is RM264
RM306 total
includes taxes & fees
15 Jun - 16 Jun
Motel 6 Maryland Heights, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
366 reviews
View
Lunch and dinner served
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
25 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
774 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,014 reviews
View
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
178 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Hollywood Casino & Hotel St. Louis and Pear Tree Inn St. Louis Airport.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.