Hotels near Mississippi River
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Mississippi River hotels
1. Sleep Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Great staff and the rooms were clean and comfortable"
Steve
The price is RM462
RM538 total
includes taxes & fees
23 Aug - 24 Aug
2. River's Edge Motel
River's Edge Motel13.6 km from Mississippi River
9.0 out of 10, Wonderful, (378 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
Brent
The price is RM327
RM371 total
includes taxes & fees
2 Aug - 3 Aug
3. The Eagles Nest Inn
The Eagles Nest Inn14.2 km from Mississippi River
9.4 out of 10, Exceptional, (25 reviews)
"Very nice place to stay loved the brick walls and wood floors leading up to the rooms"
Gary
The price is RM460
RM522 total
includes taxes & fees
30 Jul - 31 Jul
4. Riverside Inn Hannibal
Riverside Inn Hannibal25.1 km from Mississippi River
9.6 out of 10, Exceptional, (186 reviews)
"Easy no hastle accommodations. Downtown. Hot tub."
Robert
The price is RM658
RM900 total
includes taxes & fees
30 Jul - 31 Jul
5. Best Western On The River
Best Western On The River25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,000 reviews)
"Great location for all our activities!"
Carolyn
The price is RM524
RM604 total
includes taxes & fees
5 Aug - 6 Aug
6. Quality Inn & Suites Hannibal West
Quality Inn & Suites Hannibal West30 km from Mississippi River
8.0 out of 10, Very good, (1,017 reviews)
"Older property with very hospitable staff and excellent hot breakfast!"
Karen
The price is RM312
RM363 total
includes taxes & fees
9 Aug - 10 Aug
7. Oak Hill Inn & Suites
Oak Hill Inn & Suites71.8 km from Mississippi River
9.2 out of 10, Wonderful, (993 reviews)
"Breakfast was good, room was clean, and staff was nice!"
Kaia
The price is RM414
RM471 total
includes taxes & fees
24 Aug - 25 Aug
8. Heritage Hotel Quincy
Heritage Hotel Quincy47.8 km from Mississippi River
8.8 out of 10, Excellent, (422 reviews)
"Would stay again"
Dustine
The price is RM286
RM326 total
includes taxes & fees
20 Aug - 21 Aug
9. Town & Country Inn and Suites
Town & Country Inn and Suites45.2 km from Mississippi River
9.2 out of 10, Wonderful, (935 reviews)
"The room was large and clean and the breakfast tasty!"
Tracy
The price is RM549
RM625 total
includes taxes & fees
30 Jul - 31 Jul
10. Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. Peters95.3 km from Mississippi River
9.4 out of 10, Exceptional, (1,016 reviews)
"Front desk was very helpful and friendly. Breakfast was very good and staff was extremely friendly!"
DANA
The price is RM470
RM541 total
includes taxes & fees
13 Aug - 14 Aug
11. Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHG86.2 km from Mississippi River
9.4 out of 10, Exceptional, (944 reviews)
"One of the best breakfast we have had at a hotel stay."
Debbie
The price is RM470
RM563 total
includes taxes & fees
23 Aug - 24 Aug
12. Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive100.2 km from Mississippi River
9.0 out of 10, Wonderful, (1,055 reviews)
"very nice and clean room, breakfast selection was very nice, the staff was very courteous and professional. We will stay there again. "
Helmuth
The price is RM336
RM396 total
includes taxes & fees
5 Aug - 6 Aug
13. Lighthouse Inn & Suites
Lighthouse Inn & Suites25.8 km from Mississippi River
9.0 out of 10, Wonderful, (36 reviews)
"Wonderful place to stay!"
Kari
The price is RM733
RM846 total
includes taxes & fees
6 Aug - 7 Aug
14. Motel 6 Hannibal, MO
Motel 6 Hannibal, MO26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
"Clean room good staff"
Darion
The price is RM233
RM269 total
includes taxes & fees
21 Aug - 22 Aug
15. Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles104 km from Mississippi River
9.6 out of 10, Exceptional, (1,000 reviews)
"it was a nice place to stay"
Jamie
The price is RM572
RM663 total
includes taxes & fees
9 Aug - 10 Aug
16. Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal26.2 km from Mississippi River
7.6 out of 10, Good, (726 reviews)
"As always the beds at comfort inn are so comfortable. Enjoyed our stay."
Tracey
The price is RM343
RM408 total
includes taxes & fees
9 Aug - 10 Aug
17. Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal26.3 km from Mississippi River
7.2 out of 10, Good, (1,009 reviews)
"Typically Indian run hotel clean no bugs helpful staff older building the faint smell of Mumbai"
George
The price is RM258
RM297 total
includes taxes & fees
30 Jul - 31 Jul
18. Quality Inn & Suites Quincy - Downtown
Quality Inn & Suites Quincy - Downtown47.8 km from Mississippi River
8.8 out of 10, Excellent, (479 reviews)
"Great staff and nice accommodations. "
Tom
The price is RM505
RM576 total
includes taxes & fees
2 Aug - 3 Aug
19. Hampton Inn & Suites St. Louis/Alton
Hampton Inn & Suites St. Louis/Alton110.3 km from Mississippi River
9.0 out of 10, Wonderful, (699 reviews)
"the room was newly remodeled. great space wonderful bed
The staff was delightful very helpful.
breakfast was good, aple"
Ronald
The price is RM533
RM608 total
includes taxes & fees
9 Aug - 10 Aug
20. The Green Tree Inn
The Green Tree Inn95 km from Mississippi River
9.4 out of 10, Exceptional, (214 reviews)
"Really good breakfast all 3 mornings we were there. They packed a delicious picnic lunch for us to take on a hike. Room was clean and neat. Very charming small town. Would stay there again."
Vernon
The price is RM800
RM888 total
includes taxes & fees
4 Aug - 5 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Mississippi River
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Sleep Inn & Suites Hannibal West | 9.6 Exceptional 1,001 reviews | View | ||||||
 River's Edge Motel | 9.0 Wonderful 378 reviews | View | ||||||
 The Eagles Nest Inn | 9.4 Exceptional 25 reviews | View | ||||||
 Riverside Inn Hannibal | 9.6 Exceptional 186 reviews | View | ||||||
 Best Western On The River | 8.6 Excellent 1,000 reviews | View |