Sikeston

Travel Guide

Good Day Sunshine Early Morning Sunshine passes through the fog and scatters through the leaves of a tree in Scott County Missouri
Pre-teen girl walking through corn maze during fall
Columns and Dogwood Trees. Columns from an old church surrounded by colorful dog wood trees in full bloom
Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is RM440 per night from 2 Jun to 3 Jun
RM440
RM506 total
2 Jun - 3 Jun
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,001 reviews)
"Breakfast was good,pool hot tub excellent"

Reviewed on 17 May 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is RM403 per night from 14 Jun to 15 Jun
RM403
RM456 total
14 Jun - 15 Jun
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (563 reviews)
"Everything was good"

Reviewed on 10 May 2026

Hampton Inn Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is RM358 per night from 21 Jun to 22 Jun
RM358
RM408 total
21 Jun - 22 Jun
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,000 reviews)
"Breakfast was fresh and the room was clean. It's a good place to stay. Friendly staff."

Reviewed on 20 May 2026

Best Western Plus Sikeston I-55
See all 304 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel

2 out of 5
112 W Ste Maries St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free Wi-Fi, free parking and bathrobes. Popular attractions Feltz Street Park and Perryville Country Club are located ...
9.4/10 Exceptional! (3 reviews)
"Very nice clean room with comfortable bed and nice shower. Kitchenette was good with microwave and mini fridge, basic dishes. The owner was very easy to communicate with. Good location with Mary Jane’s restaurant bar next door had excellent food and nice atmosphere. My only small suggestion would ..."

Reviewed on 3 May 2026

The Atrium - A Boutique Hotel
See all properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Sikeston Depot Museum

You can spend time studying the exhibits at Sikeston Depot Museum during your travels in Sikeston. While in this family-friendly area, you can savour the top-notch restaurants.

Sikeston Depot Museum

Central Park

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this relaxing area, you can savour the top-notch restaurants.

Central Park

City of Miner Convention Center

Learn about the events happening in City of Miner Convention Center during your trip to Miner. While in this family-friendly area, you can savour the top-notch restaurants.

City of Miner Convention Center

Other places like Sikeston

Explore a world of travel with Expedia