A colonial-style building with a bell tower, palm trees, and a paved walkway.

Santa Cruz hotels from RM109

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Check prices for these dates

This weekend
24 Jul - 26 Jul
Next weekend
31 Jul - 2 Aug

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Our top choices for Santa Cruz hotels

Airport shuttle included
Seasonal outdoor pool

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (391 reviews)
"very nice place"
United States
ERNESTO
The price is RM553
RM553 total
28 Jul - 29 Jul
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lounge

2. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (279 reviews)
"The hotel truly exceeded all my expectations. The quality of the facilities, the service, and the excellent breakfast were outstanding."
United States
imilse de
The price is RM301
RM301 total
1 Aug - 2 Aug
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Outdoor pool

3. Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (388 reviews)
"Very well located three start hotel. Clean with everything you need for an in/out night. Hotel needs a redoing."
United States
jose
The price is RM442
RM442 total
8 Aug - 9 Aug
Sun Hotel
Outdoor pool, pool loungers

4. Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (146 reviews)
"Very good."
United States
Sarinela
The price is RM501
RM501 total
25 Jul - 26 Jul
Hotel Cortez
Reception

5. Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (433 reviews)
The price is RM594
RM594 total
5 Aug - 6 Aug
Camino Real Hotel
Miscellaneous

6. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (125 reviews)
"I was a solo traveler, the room was clean, I felt safe, there was a restaurant, and I even was able to walk to the zoo one day (30 min walk)! When I had to leave at 3 AM to catch a flight, the hotel helped arrange a taxi."
United States
Susanne
The price is RM219
RM219 total
5 Aug - 6 Aug
Ibis Santa Cruz DE LA Sierra
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers

7. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (110 reviews)
"Great Location"
United States
Blanca
The price is RM188
RM188 total
24 Jul - 25 Jul
Premium Suites Deluxe Aparthotel Equipetrol
Front of property

8. ChairĆŗ Eco Hotel

ChairĆŗ Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (71 reviews)
"Clean room and friendly staff "
United States
marcia
The price is RM221
RM221 total
24 Jul - 25 Jul
ChairĆŗ Eco Hotel
Outdoor pool, pool umbrellas, pool loungers

9. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (240 reviews)
"Marriot has anything and everything you need for comfort. Worth it and one of the nicest hotels in Santa Cruz."
United States
JACK
The price is RM433
RM433 total
26 Jul - 27 Jul
Marriott Santa Cruz de la Sierra Hotel
Reception

10. Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (46 reviews)
"Lovely stay for a night. Great location within easy walking distance to the center."
United States
Gabrielle
The price is RM155
RM155 total
22 Jul - 23 Jul
Lido Hotel
1 bedroom, in-room safe, desk, iron/ironing board (on request)

11. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (103 reviews)
"Great location."
United States
Ruben
The price is RM110
RM110 total
22 Jul - 23 Jul
Apart Hotel Premium Suites Santa Cruz
Exterior detail

12. TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (166 reviews)
"My go too hotel whenever I'm in town! "
United States
Pluetina
The price is RM328
RM328 total
23 Jul - 24 Jul
TRYP by Wyndham Santa Cruz
Outdoor pool

13. Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (95 reviews)
"Great location, nice and quiet neighborhood."
United States
ALEJANDRO
The price is RM195
RM195 total
5 Aug - 6 Aug
Delfines Collection Hotel By Mercure
Daily buffet breakfast for a fee

14. Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (210 reviews)
"Nice place to stay"
United States
Ricardo
The price is RM161
RM181 total
25 Jul - 26 Jul
Hotel LP Equipetrol
Egyptian cotton sheets, premium bedding, pillow-top beds, minibar

15. HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (52 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is RM191
RM253 total
25 Jul - 26 Jul
HOTEL OSHO
Lobby sitting area

16. Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (122 reviews)
"REALLY NICE HOTEL. STAFF WONDERFULL"
United States
ERNESTO
The price is RM543
RM543 total
9 Aug - 10 Aug
Novotel Santa Cruz De La Sierra
Premium bedding, down duvets, minibar, blackout curtains

17. Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (107 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is RM115
RM115 total
22 Jul - 23 Jul
Hotel G
Terrace/patio

18. Hotel Las AmƩricas

Hotel Las AmƩricas
3.0 star property
Santa Cruz
7.6 out of 10, Good, (26 reviews)
The price is RM142
RM142 total
22 Jul - 23 Jul
Hotel Las AmƩricas
Massages

19. SwissƓtel Santa Cruz De La Sierra

SwissƓtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (88 reviews)
"Great room, spacious, quiet and the shower was great"
United States
GONZALO
The price is RM412
RM412 total
17 Aug - 18 Aug
SwissƓtel Santa Cruz De La Sierra
Minibar, in-room safe, desk, soundproofing

20. Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (135 reviews)
"Everything was excellent! Clean room, delicious food, friendly staff, great location!"
United States
Heidi
The price is RM372
RM372 total
1 Aug - 2 Aug
Cosmopolitano Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Holiday Rentals in Santa Cruz

Aparthotel
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (110 reviews)
"Great Location"
Premium Suites Deluxe Aparthotel Equipetrol
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
See properties

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro GĆ¼embĆ© offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A colonial-style building with a bell tower, palm trees, and a paved walkway.

Top Santa Cruz Hotel Reviews

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

10/10 Excellent
"N/A"
Osmin 1-night trip
Posted 5 hours ago
Marriott Santa Cruz de la Sierra Hotel

More cheap stays in Santa Cruz

Ibiza Hostel

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz
The price is RM52 per night from 22 Jul to 23 Jul
RM52
RM109 total
22 Jul - 23 Jul

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveller data. This hotel offers a restaurant and free parking. Other good choices for your stay include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and TRYP by Wyndham Santa Cruz. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, Ibiza Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include residencial francia - Hostel and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. SwissƓtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Casa Por Temporadas is a top dog-friendly guest house, and offers an outdoor pool along with in-room kitchens for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and SwissƓtel Santa Cruz De La Sierra. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Novotel Santa Cruz De La Sierra are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Yotau All Suites Hotel is a top hotel with 2 outdoor swimming pools, a children's pool and 2 restaurants. A couple of other options that feature an on-site pool include Buganvillas Hotel Suites & Spa and Royal Lodge Hotel. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafƩs, zoo and cathedral. In Santa Cruz, there are 292 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Cine Center, Ethno-folkloric Museum and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26Ā°C, while the coldest months are June and July, with an average of 21Ā°C. Average annual precipitation for Santa Cruz is 1208 mm.