Hotels in Texas Medical Center, Houston

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Our top choices for Texas Medical Center hotels

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.4 out of 10, Very good, (1803)
"The hotel was great and convenient. Easy check in an check out. Will definitely stay again. "
United States
Allison
The price is RM369
RM436 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Houston Plaza/Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (2209)
"Hotel was modern and well-kept and staff were nice! Breakfast buffet was really good. A great location too. "
United States
Tammy
The price is RM475
RM559 total
includes taxes & fees
10 Jan - 11 Jan 2026
Hyatt Place Houston Medical Center

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3634)
"Great Hotel! "
United States
Delilah
The price is RM528
RM618 total
includes taxes & fees
18 Jan - 19 Jan 2026
Blossom Hotel Houston, Curio Collection by Hilton

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1005)
"Very clean room very polite staff"
United States
David
The price is RM618
RM804 total
includes taxes & fees
1 Jan - 2 Jan 2026
InterContinental Houston by IHG

Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (573)
"Our stay was excellent and will be back next time!"
United States
Marta
The price is RM528
RM618 total
includes taxes & fees
8 Jan - 9 Jan 2026
Home2 Suites by Hilton Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (1005)
"LOVE STAYING AT THE HOTEL WHEN I TRAVEL TO HOUSTON. "
United States
Ruby
The price is RM461
RM540 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hilton Garden Inn Houston Medical Center, TX

Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1209)
"I had a great stay! I travel to Houston several times a year and this is one of my favorite places to stay."
United States
Star
The price is RM475
RM559 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hyatt House Houston Medical Center

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1036)
"Great place to stay "
United States
Ernest
The price is RM556
RM692 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Westin Houston Medical Center/Museum District

Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center
8.2 out of 10, Very good, (1005)
"Clean room and friendly staff! "
United States
Amy
The price is RM395
RM464 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hampton Inn & Suites Houston Medical Center NRG Park

Residence Inn by Marriott Houston Medical Center/NRG Park

Residence Inn by Marriott Houston Medical Center/NRG Park
3.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (505)
"Spacious, clean room and nice complementary breakfast "
United States
Karen
The price is RM645
RM755 total
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn by Marriott Houston Medical Center/NRG Park

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
Texas Medical Center
8.4 out of 10, Very good, (482)
"Solid hotel and amenities"
United States
Kenneth
The price is RM451
RM528 total
includes taxes & fees
23 Jan - 24 Jan 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Americas Best Value Inn NRG Park Medical Center

Americas Best Value Inn NRG Park Medical Center
2.0 star property
Texas Medical Center
7.8 out of 10, Good, (852)
"I liked the stay. This guy Shashank at the front desk is very sweet n nice. Everything thing was good."
United States
shiva
The price is RM304
RM356 total
includes taxes & fees
4 Jan - 5 Jan 2026
Americas Best Value Inn NRG Park Medical Center

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (1001)
"Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy."
United States
Elena
The price is RM581
RM809 total
includes taxes & fees
24 Jan - 25 Jan 2026
Houston Marriott Medical Center/Museum District

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
Texas Medical Center
5.8 out of 10, (1001)
"Room was very large…"
United States
Veronica
The price is RM237
RM278 total
includes taxes & fees
11 Jan - 12 Jan 2026
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
2.5 star property
3.2 km from Texas Medical Center
9.4 out of 10, Exceptional, (1000)
"Clean, well run hotel and great location."
United States
Joan
The price is RM506
RM595 total
includes taxes & fees
8 Jan - 9 Jan 2026
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
4.6 km from Texas Medical Center
8.4 out of 10, Very good, (1404)
"Good breakfast. Nice room and common areas."
United States
William
The price is RM370
RM432 total
includes taxes & fees
1 Jan - 2 Jan 2026
DoubleTree by Hilton Hotel Houston - Greenway Plaza

Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Crowne Plaza Houston Med Ctr-Galleria Area by IHG
3.5 star property
3.9 km from Texas Medical Center
7.8 out of 10, Good, (1288)
"The staff were very friendly and helpful! The overall stay was amazing! "
United States
Timothy
The price is RM263
RM308 total
includes taxes & fees
28 Jan - 29 Jan 2026
Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Champions Club and Hotel, Houston Westchase

Champions Club and Hotel, Houston Westchase
3.0 star property
15.6 km from Texas Medical Center
8.8 out of 10, Excellent, (494)
"Very comfortable rooms! Would stay again! "
United States
LINDSEY
Champions Club and Hotel, Houston Westchase

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
3.5 star property
28.9 km from Texas Medical Center
9.2 out of 10, Wonderful, (1002)
"Great Hotel"
United States
Jessica
The price is RM305
RM351 total
includes taxes & fees
25 Jan - 26 Jan 2026
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel
4.0 star property
Downtown Houston, 7.2 km from Texas Medical Center
9.2 out of 10, Wonderful, (1372)
"Beautiful hotel very warm and inviting. "
United States
Mandi
The price is RM507
RM606 total
includes taxes & fees
11 Jan - 12 Jan 2026
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Northside

While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more of the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top Texas Medical Center Hotel Reviews

Frequently asked questions

What is Texas Medical Center like?
Texas Medical Center is a neighbourhood that travellers like for its museums, shopping and zoo. Consider a visit to Houston Zoo as part of your Texas Medical Center travel plans.
What's a favourite place to stay in Texas Medical Center?
Based on Expedia customer reviews, Hilton Garden Inn Houston Medical Center, TX is the highest ranked property in Texas Medical Center. This hotel offers a restaurant and an outdoor pool. Other top choices in the neighbourhood include Home2 Suites by Hilton Houston Medical Center, TX and InterContinental Houston by IHG.
How many hotels can I expect to find in the Texas Medical Center area?
Expedia has 177 hotels and other accommodation options in Texas Medical Center to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in Texas Medical Center, will I receive a refund?
Yes, you'll find most hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the best deals available in Texas Medical Center.
What can I see and do in this Houston neighbourhood?
Houston Zoo is an attraction you might want to check out while you're in Texas Medical Center. While you're out sightseeing, NRG Stadium and Reckling Park are a couple of additional sights to visit in Houston.
How can I get around Texas Medical Center and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at TMC Transit Center, Dryden/TMC Station or Smith Lands Station.

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