Hotels in Puerto Santa Ana, Guayaquil

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Our top choices for Puerto Santa Ana hotels

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Attentive staff and excellent breakfast and amenities."
United States
Mario
The price is RM405
RM455 total
5 Apr - 6 Apr
Wyndham Guayaquil Puerto Santa Ana

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (106 reviews)
"The property was very clean and well maintained. Lots of security. The building is on the riverfront with many excellent restaurants within a few steps. Vibrant night life which was unfortunately very noisy when trying to sleep. Within walking distance to many attractions."
United States
Carolyn
The price is RM398
RM402 total
7 Apr - 8 Apr
Luxury Suites Riverfront GYE

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (47 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is RM324
RM328 total
3 Apr - 4 Apr
River View suites Puerto Santa Ana gye

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
9.7 km from Puerto Santa Ana
The price is RM215
RM219 total
5 Apr - 6 Apr
NP Hotel & Suites

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
5.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (47 reviews)
"A lovely oasis in the city. Very relaxing and friendly service."
United States
Landy
The price is RM237
RM265 total
2 Apr - 3 Apr
Iguanazu Bed & Breakfast

Hotel del Parque

Hotel del Parque
4.5 star property
3.6 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (111 reviews)
"Friendly staff. We arrived very early and they were ablemto accommodate an early check-in. The hotel is beautiful "
Canada
Victor
The price is RM1,737
RM1,911 total
2 Apr - 3 Apr
Hotel del Parque

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is RM1,071
RM1,195 total
2 Apr - 3 Apr
Hotel Río Guayas by Art Hotels Ecuador

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,004 reviews)
"Perfect hotel for my overnight layover. 24-hour room service; helpful staff; easy and easily available shuttle to the airport. Would stay again."
United States
Alexander
The price is RM417
RM469 total
11 Apr - 12 Apr
Holiday Inn Guayaquil Airport by IHG

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
3.3 km from Puerto Santa Ana
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is RM194
RM194 total
2 Apr - 3 Apr
Hotel La Ria Durán

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 3.5 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (179 reviews)
"Clean room, staff, location"
United States
Veronica
The price is RM346
RM350 total
8 Apr - 9 Apr
Luxva Hotel Boutique

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 3.2 km from Puerto Santa Ana
8.8 out of 10, Excellent, (882 reviews)
"convenient place and clean"
United States
Allyson
The price is RM422
RM474 total
10 Apr - 11 Apr
Hilton Colon Guayaquil

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 2.9 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (635 reviews)
"Very nice place to stay ! "
United States
Diana
The price is RM364
RM411 total
3 Apr - 4 Apr
Sheraton Guayaquil Hotel

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (136 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is RM233
RM260 total
6 Apr - 7 Apr
Mansión del Río

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,001 reviews)
"Great staff!"
United States
Jeanette
The price is RM344
RM389 total
3 Apr - 4 Apr
Oro Verde Guayaquil

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (9 reviews)
"Wonderful hosts and felt like home "
United States
Tina
The price is RM283
RM287 total
2 Apr - 3 Apr
Hostal Macaw

Hotel Plaza Monte Carlo

Hotel Plaza Monte Carlo
3.0 star property
Garzota, 3.7 km from Puerto Santa Ana
8.6 out of 10, Excellent, (9 reviews)
"Breakfast was really good and nice! "
United States
Glenda
The price is RM278
RM282 total
3 Apr - 4 Apr
Hotel Plaza Monte Carlo

Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"Nice place to stay. "
United States
Joanna
The price is RM292
RM327 total
4 Apr - 5 Apr
Grand Hotel Guayaquil, an Ascend Collection Hotel

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,006 reviews)
"Very pleasant hotel - great location and excellent staff - room quiet and clean"
United States
Charles
The price is RM343
RM387 total
5 Apr - 6 Apr
TRYP by Wyndham Guayaquil Airport

Casa Veranda

Casa Veranda
2.5 star property
12.9 km from Puerto Santa Ana
The price is RM128
RM128 total
2 Apr - 3 Apr
Casa Veranda

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (615 reviews)
"Clean room and nice staff"
United States
JUAN BERNARDO
The price is RM139
RM143 total
1 May - 2 May
DC Suites Aeropuerto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Bolívar

While Bolívar may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Central Market and Malecon Mall.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Top Puerto Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 85 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.