O Brien hotels from RM177

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16 Dec - 17 Dec
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17 Dec - 18 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for O Brien hotels

Lobby
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.2 out of 10, Very good, (75)
Located in Lake City with easy access to Regal UA Cinema 90 and Lake City Mall, this motel offers convenient amenities including complimentary WiFi, free parking, and 24-hour front desk service.
"Great little motel with extremely nice staff. "
United States
Georgiy
The price is RM214
RM240 total
includes taxes & fees
18 Dec - 19 Dec
Motel 6 – Lake City, Fl – Medical Center
Lobby
Econo Lodge Live Oak

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (277)
In Live Oak, this motel offers complimentary breakfast, WiFi, and parking. Take a refreshing swim in the outdoor pool, then explore nearby Suwannee County Historical Museum and First Federal Sportsplex.
"need grab bars"
United States
Frances and Edward
The price is RM300
RM330 total
includes taxes & fees
29 Dec - 30 Dec
Econo Lodge Live Oak
Exterior
Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (515)
Tranquil surroundings create a serene atmosphere at this Live Oak hotel. Enjoy complimentary breakfast, WiFi, and parking while staying in clean, comfortable rooms. Helpful staff ensure a pleasant experience near Suwannee County Historical Museum.
"Staff was very friendly, check-in was super fast, decent room, neat and clean, comfy veds, big towels, breakfast was ok."
United States
Charlotte
The price is RM428
RM471 total
includes taxes & fees
1 Jan - 2 Jan 2026
Quality Inn & Suites Live Oak I-10 Exit 283
Desk, free WiFi, bed sheets
Royal Inn

Royal Inn

Royal Inn
2.0 star property
Live Oak
6.0 out of 10, (45)
Experience comfort at this welcoming Live Oak motel with complimentary WiFi and self parking. Located near Suwannee County Historical Museum and First Federal Sportsplex, guests enjoy 24-hour front desk service for a convenient stay.
"Good for the price "
United States
Jaiden
Royal Inn
Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (617)
Located close to Blue Sink Canoe Launch, this Live Oak hotel offers hiking trails and clean rooms with free WiFi. Enjoy the outdoor pool after exploring Stephen Foster Folk Culture Centre State Park. Business travellers appreciate the friendly staff.
"Clean rooms, very friendly staff"
United States
Kristin L
The price is RM279
RM306 total
includes taxes & fees
29 Dec - 30 Dec
Quality Inn White Springs Suwanee
Free daily buffet breakfast
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (774)
Located off the interstate, this hotel provides easy access to Suwannee County Historical Museum. Start mornings with free breakfast before exploring First Federal Sportsplex nearby. Clean rooms await after a workout in the fitness centre.
"Have stayed here whenever we are in town. Always god stay."
United States
Gregg
The price is RM494
RM544 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Live Oak by IHG
Laptop workspace, free WiFi
High Springs Country Inn

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.4 out of 10, Very good, (16)
Escape to this welcoming motel where free WiFi and parking await. Visit nearby High Springs Civic Centre Park and Museum. The 24-hour front desk ensures convenience throughout your small-town adventure.
"Great remodel of a retro motel."
United States
Kathleen
The price is RM321
RM361 total
includes taxes & fees
18 Dec - 19 Dec
High Springs Country Inn
Reception
BlueGem Motel

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (393)
This charming motel offers comfortable accommodation in High Springs with complimentary WiFi and parking. Guests appreciate the helpful staff, clean rooms, and convenient access to High Springs Civic Centre Park and Museum.
"Perfect "
United States
Geily
The price is RM452
RM508 total
includes taxes & fees
17 Dec - 18 Dec
BlueGem Motel
Exterior
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (151)
Immerse yourself in natural beauty at this High Springs cabin. Each unit offers a kitchenette and private patio. Ruth B. Kirby Gilchrist Blue Springs State Park and Poe Springs Park are just moments away, with free parking on-site.
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is RM406
RM627 total
includes taxes & fees
17 Dec - 18 Dec
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (473)
Located in Alachua, this welcoming hotel offers an outdoor pool and fitness centre just minutes from the Sports Complex. Clean rooms and helpful staff create a relaxing atmosphere, while free parking adds convenience for business and leisure travellers alike.
"Staff very helpful- clean updated facility. "
United States
bethany
The price is RM390
RM439 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Alachua I-75
Desk, blackout curtains, iron/ironing board, rollaway beds
Americas Best Value Inn Alachua

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
Alachua
4.8 out of 10, (599)
Located near Alachua Sports Complex, this budget-friendly motel offers an inviting outdoor pool for cooling off. Enjoy free WiFi and parking, with comfortable accommodation just minutes from community attractions.
"Staff was helpful and so courteous.."
United States
Christian
The price is RM261
RM294 total
includes taxes & fees
18 Dec - 19 Dec
Americas Best Value Inn Alachua
BBQ/picnic Area
Cindys Motel

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (128)
Located near Veteran's Memorial Park of Mayo and Lafayette County Library, this motel offers free WiFi and parking. Guests consistently praise the attentive staff and daily housekeeping that ensure a pleasant stay.
"Nice place"
Australia
Marie
Cindys Motel
Terrace/patio
Suwannee River Rendezvous

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (19)
Nestled in Mayo, this resort offers a scenic escape with 3 outdoor pools and The Cookin' Shack restaurant serving three daily meals. Explore nearby Peacock Springs State Park while enjoying free WiFi and parking.
"Always a good time!"
United States
Madalaine
The price is RM111
RM177 total
includes taxes & fees
15 Jan - 16 Jan 2026
Suwannee River Rendezvous
Lobby
Comfort Suites Lake City

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1001)
Enjoy the outdoor pool and free breakfast at this welcoming Lake City hotel. Located close to Regal UA Cinema 90 and Lake City Mall, guests appreciate the helpful staff, fitness centre, and convenient free parking and WiFi.
"We love to stop here when traveling to Orlando"
United States
Bridget
The price is RM441
RM496 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites Lake City
Lobby
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1003)
Soak up Florida sunshine at the outdoor pool of this welcoming hotel. Located near Regal UA Cinema 90 and Lake City Mall, it offers free breakfast, WiFi, and parking. Clean rooms and helpful staff ensure a pleasant business or leisure stay.
"Clean room, staff, everyone super helpful ."
United States
Devang
The price is RM390
RM439 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Lake City
Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1005)
Experience comfort at this Alachua hotel featuring an outdoor pool and hot tub. Enjoy complimentary breakfast, WiFi, and parking while staying close to Alachua Sports Complex. Business-friendly accommodation include in-room refrigerators and microwaves, with a 24-hour fitness centre for active travellers.
"Staff was great and the location is perfect ! "
United States
JAY
The price is RM479
RM539 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Exterior
Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1004)
Enjoy a refreshing swim in the indoor pool before grabbing a bite at The Atrium restaurant. This hotel offers free WiFi, parking, and a 24-hour fitness centre, all minutes from Regal UA Cinema 90 and Lake City Mall. Staff receives high marks from guests.
"Dog friendly. "
United States
Barbara
The price is RM389
RM438 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn & Suites Lake City by IHG
Exterior
Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (733)
Enjoy a peaceful stay at this clean, quiet hotel featuring an outdoor pool, 24-hour fitness centre, and complimentary breakfast. Located near Regal UA Cinema 90 and Lake City Mall, with free parking and helpful staff to enhance your visit.
"Great place to stay. We will be back. "
United States
Joseph
The price is RM488
RM549 total
includes taxes & fees
24 Dec - 25 Dec
Home2 Suites by Hilton Lake City
Lobby
Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (164)
Unwind at this welcoming Lake City retreat where the indoor pool refreshes morning swimmers and the hot tub soothes evening relaxers. Free breakfast, WiFi and parking enhance your stay near Regal UA Cinema 90 and Lake City Mall.
"Very clean, friendly staff, safe and quiet "
United States
Amy
The price is RM365
RM410 total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites Lake City
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1014)
Enjoy a refreshing dip in the indoor pool after a day of exploration. This hotel offers complimentary breakfast, WiFi and parking. Located near Regal UA Cinema 90 and Lake City Mall, with attentive staff ready to enhance your stay.
"Staff was great and breakfast was awesome."
United States
Derrick
The price is RM358
RM402 total
includes taxes & fees
18 Dec - 19 Dec
Best Western Plus Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

BlueGem Motel

BlueGem Motel

10/10 Excellent
"Nice motel"
Courtney 1-night trip
Posted 2 days ago
BlueGem Motel

More cheap stays in O Brien

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

3340 W US Highway 90 Lake City FL
The price is RM214 per night from 18 Dec to 19 Dec
RM214
RM240 total
18 Dec - 19 Dec
includes taxes & fees
8/10 Very Good! (71 reviews)

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Tru by Hilton Lake City. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool and complimentary high-speed (wired) Internet access. La Quinta Inn & Suite by Wyndham Lake City and Tru by Hilton Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Bob's River Place and Lafayette Blue Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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