A calm river with clear water, surrounded by dense trees and rocky banks.

O Brien hotels from RM265

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Check prices for these dates

Next weekend
10 Jul - 12 Jul
In two weeks
17 Jul - 19 Jul

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Our top choices for O Brien hotels

Individually decorated, desk, laptop workspace, iron/ironing board

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,001 reviews)
"Nice and restful place to stay"
United States
Frederick
The price is RM241
RM271 total
includes taxes & fees
8 Jul - 9 Jul
Days Inn by Wyndham Lake City I-10
Lobby

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,063 reviews)
"The location was great have many restaurants around, and the staff was very friendly"
United States
Carla
The price is RM348
RM392 total
includes taxes & fees
8 Jul - 9 Jul
Best Western Plus Lake City
Pillow-top beds, desk, laptop workspace, iron/ironing board

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,002 reviews)
"Great stay - easy - accommodating - quiet!"
United States
Paula
The price is RM399
RM449 total
includes taxes & fees
5 Aug - 6 Aug
Comfort Suites Lake City
Down duvets, pillow-top beds, blackout curtains, free WiFi

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (735 reviews)
"The room was clean, staff were very nice and the breakfast was outstanding."
United States
Michelle
The price is RM266
RM300 total
includes taxes & fees
20 Jul - 21 Jul
Super 8 by Wyndham Lake City
Breakfast area

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (530 reviews)
"Wonderful place to stay"
United States
Tamela
The price is RM431
RM484 total
includes taxes & fees
19 Jul - 20 Jul
Hampton Inn & Suites Alachua I-75
Exterior

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,007 reviews)
"The staff were amazing, great location, big rooms, great breakfast"
United States
Brittani
The price is RM423
RM476 total
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Premium bedding, desk, blackout curtains, soundproofing

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.6 out of 10, Good, (630 reviews)
"REALLY NICE PLACE, VERY CLEAN, WONDERFUL STAFF"
United States
Caroline
The price is RM264
RM297 total
includes taxes & fees
6 Jul - 7 Jul
Palms Garden Inn
Exterior

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,134 reviews)
"Enjoyed our stay"
United States
Tammie
The price is RM385
RM433 total
includes taxes & fees
19 Jul - 20 Jul
La Quinta Inn & Suite by Wyndham Lake City
Reception

The Blanche

The Blanche
2.0 star property
Lake City
9.4 out of 10, Exceptional, (194 reviews)
"Great property! Beautiful renovated!"
United States
Brandi
The price is RM605
RM680 total
includes taxes & fees
6 Jul - 7 Jul
The Blanche
BBQ/picnic Area

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,001 reviews)
"We stopped for one night. We have stayed here before when visiting. The staff is always helpful and accommodating ."
United States
William
The price is RM273
RM308 total
includes taxes & fees
6 Jul - 7 Jul
Americas Best Value Inn Lake City
Pillow-top beds, in-room safe, desk, blackout curtains

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,002 reviews)
"Great for a short stay and clean"
United States
Brizheet
The price is RM257
RM289 total
includes taxes & fees
6 Jul - 7 Jul
Days Inn by Wyndham Lake City I-75
View from property

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (227 reviews)
"Amazing spot to be out of the world."
United States
Tati
The price is RM729
RM1,160 total
includes taxes & fees
7 Jul - 8 Jul
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Free daily self-service breakfast

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very good, (1,005 reviews)
"It was clean and comfortable bed !"
United States
Glenda
The price is RM289
RM326 total
includes taxes & fees
14 Jul - 15 Jul
Quality Inn Lake City
Outdoor pool, open 9:00 AM to 10:00 PM, pool loungers

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,001 reviews)
"Breakfast menu was fresh, the room was clean, and the staff friendly and professional."
United States
Claire
The price is RM423
RM476 total
includes taxes & fees
2 Aug - 3 Aug
Hampton Inn & Suites Lake City
Lobby

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (679 reviews)
"Was great!! Clean rooms and peaceful.. Would stay here again and again.."
United States
Anthony
The price is RM254
RM280 total
includes taxes & fees
26 Jul - 27 Jul
Quality Inn White Springs Suwanee
Garden view

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.8 out of 10, Exceptional, (19 reviews)
"Calm peaceful stay, staff was very helpful and attentive. "
United States
Patrick
The price is RM509
RM865 total
includes taxes & fees
7 Jul - 8 Jul
Vista Verde Farm Retreat
Exterior

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (272 reviews)
"Had an amazing stay. The hotel was nice and clean and up to date."
United States
Mary Magdalene
The price is RM446
RM502 total
includes taxes & fees
19 Jul - 20 Jul
Courtyard By Marriott Lake City
Snack bar

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,005 reviews)
"Clean helpful staff and breakfast was good.parking good also"
United States
John
The price is RM408
RM459 total
includes taxes & fees
2 Aug - 3 Aug
Tru by Hilton Lake City
Lobby

Regal Inn

Regal Inn
2.5 star property
Lake City
8.4 out of 10, Very good, (606 reviews)
"Surprisingly well maintained and clean for the price. Lady at the front desk was kind and sweet."
United States
Johnny
The price is RM253
RM284 total
includes taxes & fees
7 Jul - 8 Jul
Regal Inn
Property amenity

TownePlace Suites by Marriott Lake City

TownePlace Suites by Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (134 reviews)
"Good hotel"
United States
Frank
The price is RM525
RM591 total
includes taxes & fees
12 Jul - 13 Jul
TownePlace Suites by Marriott Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

10/10 Excellent
"Everything was very clean and the staff was very friendly."
Sabdi 2-night trip
Posted less than an hour ago
Hampton Inn & Suites Alachua I-75

More cheap stays in O Brien

Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75

3598 W Us Highway 90 Lake City FL
The price is RM235 per night from 6 Jul to 7 Jul
RM235
RM265 total
6 Jul - 7 Jul
includes taxes & fees
5/10 (1,003 reviews)

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Tru by Hilton Lake City. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool and complimentary high-speed (wired) Internet access. La Quinta Inn & Suite by Wyndham Lake City and Tru by Hilton Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 10 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and First Federal Sportsplex in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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