Mesopotamia hotels from RM265

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Check prices for these dates

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Mesopotamia hotels

Interior
To Spiti tis Sofias

To Spiti tis Sofias

To Spiti tis Sofias
Kastoria
10.0 out of 10, Exceptional, (1)
Elegant guesthouse offering complimentary WiFi and parking near Kastoria Lake and Aquarium. Daily housekeeping ensures a tidy retreat while you explore local attractions. Just 18 minutes from Aristoteles Airport for convenient travel.
"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. "
France
Anonymous traveller
The price is RM272
RM312 total
includes taxes & fees
8 Jan - 9 Jan 2026
To Spiti tis Sofias
Exterior
Andromeda Boutique hotel

Andromeda Boutique hotel

Andromeda Boutique hotel
4.0 star property
Kastoria
8.8 out of 10, Excellent, (3)
Andromeda Boutique hotel
Breakfast, lunch and dinner served
Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel
4.0 star property
Kastoria
9.0 out of 10, Wonderful, (84)
Discover tranquility at this Kastoria spa hotel where indoor swimming and rejuvenating treatments await. Just minutes from the Folklore and Byzantine Museums, enjoy free breakfast, WiFi, and convenient parking after exploring local attractions.
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "
United States
Michal
Esperos Palace Luxury & Spa Hotel
Free daily buffet breakfast
Chloe Hotel

Chloe Hotel

Chloe Hotel
3.0 star property
Kastoria
10.0 out of 10, Exceptional, (86)
Enjoy free breakfast and parking at this Kastoria hotel with a winery and tennis court. Relax with massages and aromatherapy after exploring nearby Byzantine Museum. Helpful staff, café, and bar create a welcoming Mediterranean atmosphere.
"We enjoyed the stay, friendly staff and nice breakfast "
Australia
Fani
The price is RM420
RM484 total
includes taxes & fees
8 Jan - 9 Jan 2026
Chloe Hotel
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Kyknos De Luxe Hotel

Kyknos De Luxe Hotel

Kyknos De Luxe Hotel
Kastoria
10.0 out of 10, Exceptional, (43)
Experience comfort at this hotel featuring complimentary WiFi and parking. Near Folklore and Byzantine Museums, it offers 24-hour service. Kastoria Airport is just a 20-minute drive away.
"Very nice clean, very polite staff and great breakfast!"
United States
Vasilios
The price is RM370
RM427 total
includes taxes & fees
9 Jan - 10 Jan 2026
Kyknos De Luxe Hotel
3 restaurants, breakfast, lunch, dinner served; Greek cuisine
Limneon Resort & Spa

Limneon Resort & Spa

Limneon Resort & Spa
4.0 star property
Kastoria
9.2 out of 10, Wonderful, (197)
Embrace tranquility at this Kastoria retreat offering 3 restaurants serving Greek cuisine at Cherry Bar-Restaurant. Pamper yourself with hot stone massages at the spa, then relax at 2 bars/lounges after exploring the nearby Neolithic Lakeside Settlement.
"Wonderful stay. "
Canada
Konstantinos
The price is RM441
RM516 total
includes taxes & fees
22 Dec - 23 Dec
Limneon Resort & Spa
Property grounds
Calma Hotel & Spa

Calma Hotel & Spa

Calma Hotel & Spa
4.0 star property
Kastoria
9.6 out of 10, Exceptional, (35)
Discover Byzantine treasures near this Kastoria hotel, where a seasonal outdoor pool and spa await. Free breakfast, WiFi, and parking enhance your stay, while poolside bar, fitness centre, and sauna complete the relaxing experience.
"Pleasant stay. Good amenities. Great staff. "
New Zealand
Robert
Calma Hotel & Spa
Garden
Guesthouse Vissinokipos

Guesthouse Vissinokipos

Guesthouse Vissinokipos
Kastoria
9.4 out of 10, Exceptional, (10)
Wake up to free breakfast at this guesthouse, where a lush garden and terrace create a peaceful ambiance. Just moments from Byzantine Museum and Folklore Museum, enjoy drinks at the bar or snacks at the café after exploring historic Kastoria.
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
United States
Carmen
Guesthouse Vissinokipos
Property grounds
Anesis Hotel

Anesis Hotel

Anesis Hotel
2.0 star property
Kastoria
9.0 out of 10, Wonderful, (9)
Discover cultural treasures near this welcoming Kastoria hotel, just minutes from the Folklore and Byzantine Museums. Enjoy convenient amenities including 24-hour front desk service and room service throughout your stay.
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
Canada
Adam
The price is RM231
RM265 total
includes taxes & fees
9 Jan - 10 Jan 2026
Anesis Hotel
Exterior
Guest House Ilektra

Guest House Ilektra

Guest House Ilektra
Voio
9.6 out of 10, Exceptional, (9)
Scenic mountain retreat in Voio with lush gardens and a welcoming terrace for relaxation. Enjoy convenient amenities including an on-site restaurant, bar, free WiFi and complimentary parking while exploring this charming Greek region.
"Wonderful views, easy to find, spacious rooms, and great hospitality."
United Kingdom
Maria
The price is RM252
RM289 total
includes taxes & fees
29 Dec - 30 Dec
Guest House Ilektra
Room amenity
Guesthouse Monopati

Guesthouse Monopati

Guesthouse Monopati
Amyntaio
10.0 out of 10, Exceptional, (3)
Set near Moni Panagias Monastery and Arcturos Bear Sanctuary, this charming guesthouse offers free breakfast and WiFi. After exploring nearby attractions, enjoy lunch or dinner at the on-site restaurant Monopati while daily housekeeping ensures a comfortable stay.
Guesthouse Monopati
3 bedrooms, Internet
The Sunset Haven Kastoria Modern Lake Elegance

The Sunset Haven Kastoria Modern Lake Elegance

The Sunset Haven Kastoria Modern Lake Elegance
Kastoria
The Sunset Haven Kastoria Modern Lake Elegance
2 bedrooms
Anastasia s Kastoria Cozy Modern Garden Retreat

Anastasia s Kastoria Cozy Modern Garden Retreat

Anastasia s Kastoria Cozy Modern Garden Retreat
Kastoria
The price is RM326
RM577 total
includes taxes & fees
22 Dec - 23 Dec
Anastasia s Kastoria Cozy Modern Garden Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesopotamia Hotel Reviews

Kyknos De Luxe Hotel

Kyknos De Luxe Hotel

10/10 Excellent
"The staff was warm and welcoming. The rooms were amazing and the breakfast was fantastic. Lots of ethnic Greek foods"
Theodora 4-night trip
Posted 2 months ago
Kyknos De Luxe Hotel

More cheap stays in Mesopotamia

Anesis Hotel

Anesis Hotel

Grammou 10 Kastoria
The price is RM231 per night from 9 Jan to 10 Jan
RM231
RM265 total
9 Jan - 10 Jan 2026
includes taxes & fees

Frequently asked questions

Where is the best place for a stay in Mesopotamia?
To Spiti tis Sofias is one of the top choices for your stay based on our traveller data. This guest house offers free parking and free WiFi. Two other choices for your stay in the area are Limneon Resort & Spa and Hotel Anastassiou. See all available top hotels, or vacation rentals in Mesopotamia.
What are some of the best holiday rentals that Mesopotamia has to offer?
The Sunset Haven Kastoria Modern Lake Elegance: This holiday home rental outside of Mesopotamia offers a BBQ and free WiFi to help you feel comfortable in your new surroundings. See all vacation rentals in Mesopotamia.
If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.
What is staying in Mesopotamia like?
Travellers to Mesopotamia will find plenty to explore and enjoy. There are 46 hotels and other accommodation options in the surrounding area. Find out more about Mesopotamia.
What are the top places to visit in Mesopotamia?
Places to visit in the wider area include Kastoria Aquarium, Kastoria Lake and Dragon's Lair. You'll also find Folklore Museum of Kastoria and Neolithic Lakeside Settlement in the area. Take a look at what more there is to see and do in Expedia's Mesopotamia guide.
What's the seasonal weather like in Mesopotamia?
The hottest months are usually August and July, with an average temperature of 20°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Mesopotamia is 707 mm.