Hotels near Mayo Clinic Health System

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic Health System hotels

Exterior
The Lismore Eau Claire - a DoubleTree by Hilton

The Lismore Eau Claire - a DoubleTree by Hilton

The Lismore Eau Claire - a DoubleTree by Hilton
4.0 star property
Downtown Eau Claire, 1 km from Mayo Clinic Health System
9.4 out of 10, Exceptional, (1003)
"Clean room, friendly staff."
United States
Jeffrey
The price is RM395
RM448 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Lismore Eau Claire - a DoubleTree by Hilton
Terrace/patio
The Oxbow Hotel

The Oxbow Hotel

The Oxbow Hotel
3.0 star property
Downtown Eau Claire, 1.1 km from Mayo Clinic Health System
9.2 out of 10, Wonderful, (1001)
"Clean room, excellent location and a terrific bar/restaurant."
United States
Shawn
The price is RM430
RM528 total
includes taxes & fees
5 Jan - 6 Jan 2026
The Oxbow Hotel
Property amenity
SpringHill Suites by Marriott Eau Claire

SpringHill Suites by Marriott Eau Claire

SpringHill Suites by Marriott Eau Claire
2.0 star property
1.7 km from Mayo Clinic Health System
9.6 out of 10, Exceptional, (166)
"Great staff and clean"
United States
Danielle
The price is RM348
RM395 total
includes taxes & fees
11 Jan - 12 Jan 2026
SpringHill Suites by Marriott Eau Claire
Indoor pool, pool loungers
Hampton Inn Eau Claire

Hampton Inn Eau Claire

Hampton Inn Eau Claire
2.5 star property
West University, 2.4 km from Mayo Clinic Health System
9.0 out of 10, Wonderful, (1003)
"Everything related to our stay was fabulous. Will stay there again."
United States
Diane
The price is RM328
RM373 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Eau Claire
Terrace/patio
Holiday Inn Express & Suites Eau Claire West I-94 by IHG

Holiday Inn Express & Suites Eau Claire West I-94 by IHG

Holiday Inn Express & Suites Eau Claire West I-94 by IHG
2.5 star property
West University, 2.4 km from Mayo Clinic Health System
9.0 out of 10, Wonderful, (835)
"So clean, quiet, and the front staff were very helpful to me when I asked about a local event. "
United States
Jodi
The price is RM426
RM484 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Eau Claire West I-94 by IHG
Indoor pool
Quality Inn & Suites Eau Claire University Area

Quality Inn & Suites Eau Claire University Area

Quality Inn & Suites Eau Claire University Area
2.5 star property
West University, 2.8 km from Mayo Clinic Health System
7.8 out of 10, Good, (858)
"Small older hotel, *looks can be deceiving, but it was just right for the price"
United States
Jennelle
The price is RM259
RM294 total
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn & Suites Eau Claire University Area
Desk, soundproofing, WiFi, bed sheets
Scottish Inns & Suites Eau Claire

Scottish Inns & Suites Eau Claire

Scottish Inns & Suites Eau Claire
2.5 star property
West University, 2.7 km from Mayo Clinic Health System
7.8 out of 10, Good, (552)
"Friendly staff."
United States
Holly
The price is RM240
RM273 total
includes taxes & fees
25 Jan - 26 Jan 2026
Scottish Inns & Suites Eau Claire
Premium bedding, pillow-top beds, desk, iron/ironing board
Super 8 by Wyndham Eau Claire WI

Super 8 by Wyndham Eau Claire WI

Super 8 by Wyndham Eau Claire WI
2.0 star property
West University, 2.7 km from Mayo Clinic Health System
7.4 out of 10, Good, (1001)
"Room was very clean shower faucet handle had an issue and continental breakfast. They really need to look at their food so it’s not sitting there getting old and stale old dried out bread."
United States
Wesley
The price is RM237
RM269 total
includes taxes & fees
17 Jan - 18 Jan 2026
Super 8 by Wyndham Eau Claire WI
Desk, free WiFi, bed sheets
Motel 6 Eau Claire, WI

Motel 6 Eau Claire, WI

Motel 6 Eau Claire, WI
2.0 star property
West University, 2 km from Mayo Clinic Health System
6.4 out of 10, (1003)
"Good place to stay"
United States
Dwayne
The price is RM200
RM227 total
includes taxes & fees
31 Dec - 1 Jan 2026
Motel 6 Eau Claire, WI
Private kitchen
The Mckinley House 3 Bedroom Condo

The Mckinley House 3 Bedroom Condo

The Mckinley House 3 Bedroom Condo
3.0 star property
Third Ward, 2 km from Mayo Clinic Health System
The price is RM479
RM2,180 total
includes taxes & fees
3 Jan - 4 Jan 2026
The Mckinley House 3 Bedroom Condo
Free daily buffet breakfast
Best Western Plus Eau Claire Conference Center

Best Western Plus Eau Claire Conference Center

Best Western Plus Eau Claire Conference Center
2.5 star property
West University, 3.3 km from Mayo Clinic Health System
8.8 out of 10, Excellent, (1002)
"Room was clean and quiet. Great location, right off the interstate "
United States
Benjamin
The price is RM361
RM410 total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Plus Eau Claire Conference Center
Front of property
Otter Creek Eau Claire Altoona

Otter Creek Eau Claire Altoona

Otter Creek Eau Claire Altoona
4.0 star property
5.1 km from Mayo Clinic Health System
9.8 out of 10, Exceptional, (433)
"Great place"
United States
Stacy
The price is RM430
RM498 total
includes taxes & fees
18 Jan - 19 Jan 2026
Otter Creek Eau Claire Altoona
Exterior
Staybridge Suites Eau Claire - Altoona by IHG

Staybridge Suites Eau Claire - Altoona by IHG

Staybridge Suites Eau Claire - Altoona by IHG
3.0 star property
4.6 km from Mayo Clinic Health System
9.4 out of 10, Exceptional, (815)
"Very clean and quiet room! Wonderful breakfast!"
United States
Erika
The price is RM444
RM499 total
includes taxes & fees
27 Dec - 28 Dec
Staybridge Suites Eau Claire - Altoona by IHG
Lobby
Fairfield Inn & Suites by Marriott Eau Claire Chippewa Falls

Fairfield Inn & Suites by Marriott Eau Claire Chippewa Falls

Fairfield Inn & Suites by Marriott Eau Claire Chippewa Falls
3.0 star property
5.7 km from Mayo Clinic Health System
9.6 out of 10, Exceptional, (514)
"Excellent hotel!"
United States
Craig
The price is RM421
RM477 total
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites by Marriott Eau Claire Chippewa Falls
Property amenity
Residence Inn by Marriott Eau Claire

Residence Inn by Marriott Eau Claire

Residence Inn by Marriott Eau Claire
3.0 star property
5.9 km from Mayo Clinic Health System
9.6 out of 10, Exceptional, (240)
"Room extremely clean Hotel staff wonderful "
United States
Kathy
The price is RM453
RM514 total
includes taxes & fees
1 Jan - 2 Jan 2026
Residence Inn by Marriott Eau Claire
Laptop workspace, iron/ironing board, free WiFi, bed sheets
AmeriVu Inn & Suites

AmeriVu Inn & Suites

AmeriVu Inn & Suites
2.5 star property
4.5 km from Mayo Clinic Health System
8.2 out of 10, Very good, (457)
"Was a clean and simple place to stay. Had hot coffee & Hot chocolate "
United States
Veronica
The price is RM237
RM269 total
includes taxes & fees
27 Dec - 28 Dec
AmeriVu Inn & Suites
Aerial view
Econo Lodge Inn & Suites Eau Claire South

Econo Lodge Inn & Suites Eau Claire South

Econo Lodge Inn & Suites Eau Claire South
2.0 star property
Oakwood Hills, 6.2 km from Mayo Clinic Health System
9.0 out of 10, Wonderful, (1001)
"Very nice staff and rooms!"
United States
Caroline
The price is RM262
RM305 total
includes taxes & fees
25 Jan - 26 Jan 2026
Econo Lodge Inn & Suites Eau Claire South
Terrace/patio
The Fairway

The Fairway

The Fairway
4.0 star property
4.7 km from Mayo Clinic Health System
8.6 out of 10, Excellent, (10)
"The manager and staff were excellent! The apartment was incredibly nice. If I move to WI, I’ll rent a unit!!! "
United States
nancy
The price is RM455
RM1,281 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Fairway
Exterior
Home2 Suites by Hilton Eau Claire South

Home2 Suites by Hilton Eau Claire South

Home2 Suites by Hilton Eau Claire South
3.0 star property
Oakwood Hills, 6.9 km from Mayo Clinic Health System
9.0 out of 10, Wonderful, (698)
"Very clean, friendly staff "
United States
Kathleen
The price is RM362
RM410 total
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites by Hilton Eau Claire South
Exterior
Best Western Eau Claire South

Best Western Eau Claire South

Best Western Eau Claire South
2.5 star property
Oakwood Hills, 7.3 km from Mayo Clinic Health System
9.0 out of 10, Wonderful, (905)
"Great place to stay, good location "
United States
Margaret
The price is RM306
RM347 total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Eau Claire South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mayo Clinic Health System Hotel Reviews

The Lismore Eau Claire - a DoubleTree by Hilton

The Lismore Eau Claire - a DoubleTree by Hilton

10/10 Excellent
"Very nice room"
Jane 1-night trip
Posted 4 days ago
The Lismore Eau Claire - a DoubleTree by Hilton

Hotels near other Mayo Clinic Health System attractions

Afternoon view of the farmer's market with christmas decoration

Downtown Farmers Market

4.6/5 (36 reviews)
You can do some window-shopping at Downtown Farmers Market during your visit to Eau Claire. Experience the entertainment venues and festivals in this family-friendly area.
See properties
Carson Park, Eau Claire, Wisconsin

Carson Park

4.4/5 (112 reviews)
Explore the great outdoors at Carson Park, a lovely green space in Eau Claire. Discover the waterfalls and breweries in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Health System?
Mayo Clinic Health System is located in Eau Claire. If you're looking for a convenient place to stay, take a look at the 16 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Mayo Clinic Health System?
The Lismore Eau Claire - a DoubleTree by Hilton is one of the top choices for your stay based on our traveller data, and this hotel offers 2 bars and a restaurant. It's located just a short 0.6 mi (1 km) from Mayo Clinic Health System. Another good choice is The Oxbow Hotel, located just 0.7 mi (1.1 km) away.
How many hotels will I be able to find near Mayo Clinic Health System?
Expedia has 16 hotels and other accommodation options within a mile from Mayo Clinic Health System.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Health System, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best options available near Mayo Clinic Health System.
What can I see and do near Mayo Clinic Health System?
Chippewa Valley Museum, Paul Bunyan Logging Camp Museum and Schlegelmilch-McDaniel House feature captivating exhibits. You can enjoy live performances at Pablo Center at the Confluence and Grand Little Theater. Spend some time exploring the the natural beauty of Carson Park, Florian Gardens and Lowes Creek County Park.