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Los Osos Spa Hotels

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Check availability on Los Osos Hotels with Spa

Tonight
4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Los Osos Hotels with Spa

Outdoor pool
Sea Pines Resort

Sea Pines Resort

3.0 star property
Los Osos
8.2 out of 10, Very good, (410)
"Nice staff."
United States
Ann
Sea Pines Resort
Bathroom
Madonna Inn

Madonna Inn

3.5 star property
San Luis Obispo
9.2 out of 10, Wonderful, (1316)
"Fun place"
United States
Kyle
The price is RM613
RM836 total
includes taxes & fees
8 Dec - 9 Dec
Madonna Inn
Property entrance
Avila Village Inn

Avila Village Inn

3.5 star property
Avila Beach
9.2 out of 10, Wonderful, (1001)
"The property and rooms were beautiful! We really enjoyed our weekend here and are planning to stay again!"
United States
Cathy
Avila Village Inn
Restaurant
The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection

2.5 star property
Arroyo Grande
9.6 out of 10, Exceptional, (1000)
"The room was super comfortable and clean. They offered a great breakfast too!"
United States
kim
The price is RM560
RM636 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Agrarian Hotel, BW Signature Collection
Reception
HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection

4.0 star property
Downtown San Luis Obispo
9.2 out of 10, Wonderful, (466)
"We had a great stay"
United States
ADALBERT
The price is RM831
RM1,085 total
includes taxes & fees
11 Dec - 12 Dec
HOTEL CERRO, Autograph Collection
Property grounds
Avila La Fonda Hotel

Avila La Fonda Hotel

4.0 star property
Avila Beach
9.6 out of 10, Exceptional, (1001)
"Very nice hotel. Great for and rest and relaxation kind of vacation"
United States
Princess
The price is RM848
RM954 total
includes taxes & fees
11 Dec - 12 Dec
Avila La Fonda Hotel
Exterior
Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B

3.5 star property
Cayucos
9.8 out of 10, Exceptional, (194)
"Great place to stay"
United States
Jason
The price is RM719
RM809 total
includes taxes & fees
7 Dec - 8 Dec
Cayucos Sunset Inn B&B
Living area
Hotel San Luis Obispo

Hotel San Luis Obispo

4.5 star property
Downtown San Luis Obispo
9.4 out of 10, Exceptional, (544)
"Beautiful room and nice rooftop bar!"
United States
Chizuru
The price is RM1,107
RM1,257 total
includes taxes & fees
10 Dec - 11 Dec
Hotel San Luis Obispo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Los Osos Hotel Reviews

La Cuesta Inn, BW Signature Collection

La Cuesta Inn, BW Signature Collection

10/10 Excellent
"Clean room, friendly staff "
Elizabeth 2-night trip
Posted 12 hours ago
La Cuesta Inn, BW Signature Collection

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Frequently asked questions

Looking for a spa hotel in Los Osos?
Forget the stress of everyday life and book yourself a hotel with a spa. Discover the beaches in Los Osos—worth a picture or two! Take part in recreational activities such as golf during your holiday. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Los Osos?
Sea Pines Resort is a top spa hotel featuring a golf course, a bar and a restaurant. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages and couples treatments.
How many spa hotels will I find in Los Osos?
Among Expedia's 45 accommodation options in Los Osos, there is 1 spa hotel.
What's there to see and do in Los Osos?
Experience Los Osos with a stop at Los Osos Oaks State Reserve, Elfin Forest Preserve and Montaña de Oro State Park. If you have a bit of extra time while you're in the area, you might want to check out Morro Bay State Park and Morro Coast Audubon Society Sweet Springs Nature Preserve.
What is a Los Osos spa hotel?
Spa hotels in Los Osos provide lodging and have an on-site spa which offers services such as facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.