Top 10 Hotels Near Six Mile Cypress Slough Preserve in Fort Myers for 2026

A wooden boardwalk through a dense forest with green foliage and a clear blue sky.

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Our top choices for Six Mile Cypress Slough Preserve hotels

A swimming pool with a tiled deck, a building with multiple windows, and a cloudy sky.

A gym with treadmills, dumbbells, and a sign indicating free Wi-Fi in all rooms.

A hotel room with a bed, wooden flooring, a window, a heater, a shelf with shoes, and a wall-mounted lamp.

1. HomeTowne Studios by Red Roof Fort Myers

3 km from Six Mile Cypress Slough Preserve

Vito

RM242

RM270 total

includes taxes & fees

22 Nov - 23 Nov

A Holiday Inn Express building with a modern design, featuring a flat facade and a covered entrance area.

A hotel room with a bed, desk, chair, TV, and a bathroom visible through an open door.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A paved outdoor area with palm trees, string lights, and outdoor seating.

2. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor, 6.3 km from Six Mile Cypress Slough Preserve

Brian

RM408

RM455 total

includes taxes & fees

30 Oct - 31 Oct

A swimming pool with a 3 FT depth marker, outdoor seating, and a clear sky.

A spacious restaurant with a central island, bar area, and seating arrangements.

A hotel room with a large bed, a desk with a chair, a television, and a wardrobe.

A modern kitchen with a wooden island, a backsplash, and a map on the wall.

3. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes, 9.8 km from Six Mile Cypress Slough Preserve

Andrew Charles

RM486

RM541 total

includes taxes & fees

27 Oct - 28 Oct

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

A modern kitchen with a microwave, coffee machines, and a trash bin.

A modern kitchen with a microwave, sink, and wooden shelves.

A modern kitchen area with a bar counter, seating, and a coffee station.

4. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor, 5.6 km from Six Mile Cypress Slough Preserve

Cesar

RM224

RM250 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

A hotel room with two beds, a desk, and a chair.

A gym with treadmills, ellipticals, and a stationary bike, featuring large windows and motivational posters.

A hotel lobby with a reception desk, seating area, and a restaurant.

5. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor, 4.6 km from Six Mile Cypress Slough Preserve

yudeisis

RM268

RM299 total

includes taxes & fees

24 Oct - 25 Oct

An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

A hotel lobby with a brown sofa, a matching armchair, and a small table. There are three framed pictures on the wall, a wooden cabinet, and a carpeted floor.

A reception desk with a sign reading "Comfort Inn & Suites" and two monitors on either side.

A Comfort Inn & Suites hotel with a covered entrance, palm trees, and a well-lit facade.

6. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor, 4.6 km from Six Mile Cypress Slough Preserve

Erika

RM305

RM340 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with a fire pit, outdoor furniture, and a covered patio.

A modern living room with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a ceiling light fixture.

A modern kitchen with wooden cabinets, a white countertop, and a fruit basket.

A multi-story hotel with a modern design, featuring a central entrance with a covered area and a parking lot with marked spaces.

7. TownePlace Suites by Marriott Fort Myers Gulf Coast

9.3 km from Six Mile Cypress Slough Preserve

Andrei

RM388

RM432 total

includes taxes & fees

30 Oct - 31 Oct

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

A covered outdoor seating area with wooden beams, white lattice railings, and colorful cushions.

A modern lounge area with a sofa, two yellow ottomans, a small round table, and a printer on a wooden side table.

A pool area with lounge chairs, a gazebo, and a blue umbrella.

8. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor, 3.6 km from Six Mile Cypress Slough Preserve

marleen

RM325

RM362 total

includes taxes & fees

30 Oct - 31 Oct

A modern kitchen with wooden cabinets, stainless steel appliances, a central island with blue cushioned stools, and a large pendant light.

A conference room with tables covered in blue tablecloths, equipped with chairs and water glasses.

A gym with treadmills, elliptical machines, and exercise balls.

A room with a green armchair, a patterned sofa, a small round table with a teal lamp, and a framed succulent plant.

9. Homewood Suites by Hilton - Fort Myers

Villas, 5.1 km from Six Mile Cypress Slough Preserve

Jose

RM430

RM480 total

includes taxes & fees

29 Oct - 30 Oct

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a building.

A hotel room with a TV, sofa, coffee table, desk, and a bathroom visible in the background.

A Best Western Inn & Suites sign on a building with a clear blue sky and palm trees.

10. Best Western Fort Myers Inn & Suites

3.5 km from Six Mile Cypress Slough Preserve

Azael

RM298

RM332 total

includes taxes & fees

25 Oct - 26 Oct

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

A hotel with multiple floors, a parking lot, and a sunset sky.

A modern hotel lobby with a central counter, two refrigerators stocked with beverages, and shelves with snacks.

A modern kitchen with a coffee station, stainless steel appliances, and wooden cabinets.

11. Comfort Suites Fort Myers East I-75

9.6 km from Six Mile Cypress Slough Preserve

Richard

RM368

RM410 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A modern hotel room with a wooden desk, a flat-screen TV, a chair, a wardrobe, and a framed picture on the wall.

A swimming pool with lounge chairs and palm trees.

A coffee station with two coffee machines, a coffee press, and various coffee cups and containers.

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

12.1 km from Six Mile Cypress Slough Preserve

MARYTE

RM412

RM460 total

includes taxes & fees

28 Oct - 29 Oct

A multi-level hotel atrium with balconies, seating areas, and a central courtyard.

An outdoor patio with wicker furniture, potted plants, and a view of a building with large windows.

A multi-level hotel atrium with balconies, seating areas, and indoor plants.

A hotel with a red facade, multiple floors, and palm trees in the foreground.

13. Embassy Suites by Hilton Fort Myers Estero

16.3 km from Six Mile Cypress Slough Preserve

Laura

RM499

RM556 total

includes taxes & fees

29 Oct - 30 Oct

A modern dining area with a central island, multiple tables, and chairs.

A multi-story hotel with a modern facade, a covered entrance, and a landscaped front area.

A hotel room with a large bed, a desk, a chair, and a television.

A modern hotel lobby with a leather sofa, a reception desk, and a seating area with a patterned rug.

14. Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

15.3 km from Six Mile Cypress Slough Preserve

Mauricio

RM447

RM499 total

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with a reception desk, a sofa, and a dining area with chairs and tables.

A business center with a reception desk, computer station, and a counter with a coffee machine.

15. Quality Inn & Suites Lehigh Acres Fort Myers

17.2 km from Six Mile Cypress Slough Preserve

Robert

RM229

RM255 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

A swimming pool with a stone wall and palm trees, surrounded by a building with large windows and outdoor seating.

An outdoor patio area with tables and chairs, string lights, and potted plants.

A modern reception area with a large abstract mural, a wooden reception desk, and a seating area with a long table and chairs.

16. Doubletree by Hilton Fort Myers at Bell Tower Shops

Villas, 5.2 km from Six Mile Cypress Slough Preserve

James

RM430

RM480 total

includes taxes & fees

29 Oct - 30 Oct

An outdoor patio with yellow chairs and red umbrellas, a fire pit, and a modern building in the background.

A modern breakfast area with a self-service station, seating, and a refrigerator stocked with beverages.

A hotel room with a bed, a desk with a computer, a chair, a sofa, a mirror, and a nightstand with a lamp.

A modern hotel lobby with a seating area, a reception desk, and a flat-screen TV.

17. Home2 Suites by Hilton Fort Myers Airport

8.2 km from Six Mile Cypress Slough Preserve

Nancy

RM432

RM481 total

includes taxes & fees

31 Oct - 1 Nov

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows.

A rooftop patio with outdoor seating, a pool, and palm trees.

A modern living room with a blue sofa, red armchairs, and a coffee table. There are two lamps and a wall art piece above the sofa.

18. Hampton Inn & Suites Fort Myers - Colonial Blvd

3.4 km from Six Mile Cypress Slough Preserve

Bibi

RM447

RM499 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with a stone fire pit, seating, and string lights.

A modern dining area with hexagonal pendant lights, a large window with a view, and a flat-screen TV mounted on the wall.

A bar area with a long counter, multiple bar stools, a television screen, and a wine rack with bottles.

A modern reception area with a reception desk, a bookshelf, and a decorative wall with text.

19. SpringHill Suites by Marriott Fort Myers Estero

16.3 km from Six Mile Cypress Slough Preserve

Darryl

RM455

RM508 total

includes taxes & fees

29 Oct - 30 Oct

A clean, modern hotel reception area with a blue sign indicating face masks are required for all guests.

A swimming pool with a tiled deck, lounge chairs, and umbrellas.

A hotel room with a minibar, a dining area with a table and chairs, and a large potted plant.

A gym with exercise equipment, a red exercise ball, and a rack of dumbbells.

20. Hilton Garden Inn Fort Myers Airport/FGCU

Miromar Lakes, 9.7 km from Six Mile Cypress Slough Preserve

Daniel

RM482

RM538 total

includes taxes & fees

29 Oct - 30 Oct

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Compare popular hotels close to Six Mile Cypress Slough Preserve

Property	Property class	Guest rating
HomeTowne Studios by Red Roof Fort Myers	8.8 Excellent 114 reviews	View
Holiday Inn Express & Suites Fort Myers Airport by IHG	9.4 Exceptional 1,207 reviews	View
Drury Inn & Suites Fort Myers Airport FGCU	9.6 Exceptional 1,003 reviews	View
Extended Stay America Premier Suites - Fort Myers - Airport	9.0 Wonderful 1,153 reviews	View
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park	8.2 Very good 1,787 reviews	View

Top Six Mile Cypress Slough Preserve Hotel Reviews

Courtyard by Marriott Fort Myers Cape Coral

8/10 Good

"Convenient to the airport"

Quality Suites Fort Myers I-75

10/10 Excellent

"For the price, this hotel was exceptional. The woman at the front desk who checked me in was polite and attentive. Even though she was mid-conversation with a colleague, she immediately put that conversation on hold to prioritize checking me in (this professionalism really stood out to me). As for amenities, the pool was closed so I didn't assess, but the lobby breakfast area seemed clean and pleasant. The room--there were a few chipped paint marks on the wall, but the most important things were recently renovated and clean: the shower and the toilet had new caulking, the water pressure was good and the drains didn't clog, the pillows and the bed were comfortable and fresh. All-in-all, it exceeded expectations."

Comfort Inn & Suites Fort Myers Airport

8/10 Good

"The property locos very clean and well mantained. Very clean. I have stayed 3 times and for you I will go back again."

HomeTowne Studios by Red Roof Fort Myers

8/10 Good

"Clean room and nice staff"

Landing Fort Myers Near Highland Pines

8/10 Good

"Property was a good space for our family of four. It provided everything we needed re: cooking and cleaning. Pool area was very nice."

Hilton Garden Inn Ft Myers

10/10 Excellent

"I stay often in Fort Myers (family), this is 1st at Garden Inn, I will definitely stay here in the future. Everything was immaculate, staff is friendly and ever so helpful. The rates were less than what I had been paying for someplace a few mins closer to the family. Discovered Garden Inn was <5 mins further, worth the extra few mins at less the cost. We ordered a breakfast to take to our room, cooked to order and plentiful."

Home2 Suites by Hilton Fort Myers Colonial Blvd

10/10 Excellent

"Clean rooms. Helpful front desk, very welcoming."

Quality Inn Fort Myers Cape Coral

10/10 Excellent

"I’ll be back"

Suburban Studios Fort Myers Cape Coral

8/10 Good

"OK, so upon arrival, I guess she didn’t recognize that I had a service card with me. Reason why I gave him four as the total to stay was because they paid us sign a waiver and put a deposit down on a service dog, which is technically illegal otherwise I was fine with the area that they put us at first floor cause it was a dog one of the More let’s just say abuse rooms because of the animals and I get that no problem there love the little kitchenette we didn’t use it but loved it. We’ll stay again, but they just need to know that ADA only says that they can ask what their service for and that’s pretty much there and they can’t ask for Me Mee for legal paperwork. She didn’t ask for that but the hotel in so many words by handing us a paperwork saying that we were legally responsible for adult. It didn’t make sense I just think that they Moore hotel should know the ADA Americans but disabilities rules regulations legal questions cause I not by her. She was lovely, but she’s like I have no choice. He’s part of my job. They make me do this.!"

Other attractions near Six Mile Cypress Slough Preserve

Brookshire Bath and Tennis Club

Catch an event at Brookshire Bath and Tennis Club during your trip to Fort Myers.

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Topgolf

You can take time to visit Topgolf during your travels to Fort Myers. Amble around the area's beautiful beaches or attend a baseball game.

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Hammond Stadium

Catch an event at Hammond Stadium during your trip to Fort Myers.

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Lee Health Sports Complex

8.6/10 (432 reviews)

Catch an event at Lee Health Sports Complex during your trip to Fort Myers. Stroll along the seaside in this family-friendly area or visit its top-notch restaurants.

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Calusa Nature Center and Planetarium

You can spend time browsing the exhibits at Calusa Nature Center and Planetarium in Fort Myers. Stroll along the beautiful beaches or attend a baseball game in the area.

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Eagle Ridge Golf Club

Enjoy a round of golf in Fort Myers at Eagle Ridge Golf Club. Stroll along the seaside or discover the beautiful sunsets in this family-friendly area.

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The Ranch Concert Hall & Saloon

You can get tickets for a performance at The Ranch Concert Hall & Saloon during your trip to Fort Myers. In the area, take in the entertainment choices and beautiful sunsets.

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Regal Belltower

You can take time to visit Regal Belltower during your travels to Fort Myers. Amble around this relaxing area's beautiful beaches and enjoy its top-notch restaurants.

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Frequently asked questions

What's the area like around Six Mile Cypress Slough Preserve?

Six Mile Cypress Slough Preserve is located in a family-friendly area of Fort Myers known for its beautiful beaches and bird watching. If you're looking for a convenient place to stay, take a look at the 21 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Six Mile Cypress Slough Preserve?

Landing Fort Myers Near Highland Pines is one of the top choices for your stay based on our traveller data, and this aparthotel offers an outdoor pool and free parking. It's located just a short 1 mi (1.6 km) from Six Mile Cypress Slough Preserve. Other good choices within 5 miles include Baymont by Wyndham Fort Myers Central and Hampton Inn Fort Myers-Airport & I-75.

How many hotels are there close to Six Mile Cypress Slough Preserve?

Expedia has 21 hotels and other accommodation options within a mile from Six Mile Cypress Slough Preserve.

If I need to cancel the hotel reservation for my stay near Six Mile Cypress Slough Preserve, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals available near Six Mile Cypress Slough Preserve.

What can I see and do near Six Mile Cypress Slough Preserve?

You can check out the local talent at Barbara B Mann Hall, The Ranch Concert Hall & Saloon and Broadway Palm Dinner Theatre. You might spend a leisurely day outdoors at Lakes Regional Park and Dunbar Park. Calusa Nature Center and Planetarium, Alliance for the Arts and Railroad Museum of South Florida are fun stops for the whole family while you're in town.

Hotels near Six Mile Cypress Slough Preserve

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Treat yourself

Be picky

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Our top choices for Six Mile Cypress Slough Preserve hotels

1. HomeTowne Studios by Red Roof Fort Myers

2. Holiday Inn Express & Suites Fort Myers Airport by IHG

3. Drury Inn & Suites Fort Myers Airport FGCU

4. Extended Stay America Premier Suites - Fort Myers - Airport

5. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

6. Comfort Inn & Suites Fort Myers Airport

7. TownePlace Suites by Marriott Fort Myers Gulf Coast

8. Hampton Inn Fort Myers-Airport & I-75

9. Homewood Suites by Hilton - Fort Myers

10. Best Western Fort Myers Inn & Suites

11. Comfort Suites Fort Myers East I-75

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

13. Embassy Suites by Hilton Fort Myers Estero

14. Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

15. Quality Inn & Suites Lehigh Acres Fort Myers

16. Doubletree by Hilton Fort Myers at Bell Tower Shops

17. Home2 Suites by Hilton Fort Myers Airport

18. Hampton Inn & Suites Fort Myers - Colonial Blvd

19. SpringHill Suites by Marriott Fort Myers Estero

20. Hilton Garden Inn Fort Myers Airport/FGCU

Compare popular hotels close to Six Mile Cypress Slough Preserve

Top Six Mile Cypress Slough Preserve Hotel Reviews

Courtyard by Marriott Fort Myers Cape Coral

Quality Suites Fort Myers I-75

Comfort Inn & Suites Fort Myers Airport

HomeTowne Studios by Red Roof Fort Myers

Landing Fort Myers Near Highland Pines

Hilton Garden Inn Ft Myers

Home2 Suites by Hilton Fort Myers Colonial Blvd

Quality Inn Fort Myers Cape Coral

Suburban Studios Fort Myers Cape Coral

Other attractions near Six Mile Cypress Slough Preserve

Brookshire Bath and Tennis Club

Topgolf

Hammond Stadium

Lee Health Sports Complex

Calusa Nature Center and Planetarium

Eagle Ridge Golf Club

The Ranch Concert Hall & Saloon

Regal Belltower

Frequently asked questions