Hotels in South Central Houston, Houston

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Central Houston hotels

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very good, (1,948 reviews)
"Great stay and clean room"
United States
Ethel
The price is RM536
RM631 total
includes taxes & fees
5 Jul - 6 Jul
Hilton Houston Plaza/Medical Center

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,157 reviews)
"Clean room,restaurant exceptional,excellent staff."
United States
Craig
The price is RM529
RM658 total
includes taxes & fees
6 Jun - 7 Jun
The Westin Houston Medical Center/Museum District

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,006 reviews)
"Great stay, nice staff"
United States
Allen David
The price is RM636
RM824 total
includes taxes & fees
7 Jun - 8 Jun
InterContinental Houston by IHG

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (158 reviews)
"Great place. The staff is very friendly and the place is clean."
United States
Fernando
The price is RM384
RM449 total
includes taxes & fees
7 Jun - 8 Jun
Downtowner Inns - Houston Downtown

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,001 reviews)
"Nice and helpful staff, clean rooms, nice amenities "
United States
Andrea
The price is RM755
RM1,015 total
includes taxes & fees
6 Jun - 7 Jun
Houston Marriott Medical Center/Museum District

Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (47 reviews)
"Very chic, very interesting room. Love this place"
United States
Chase
The price is RM755
RM1,001 total
includes taxes & fees
7 Jun - 8 Jun
Sentral Forme Houston

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,011 reviews)
"Overall great hotel. Definitely will be staying here again. Shout out to the staff crew."
United States
Vincent
The price is RM878
RM1,210 total
includes taxes & fees
5 Jun - 6 Jun
Hotel Zaza Houston Museum District

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (597 reviews)
"was ok"
United States
Guillermo
The price is RM596
RM697 total
includes taxes & fees
7 Jun - 8 Jun
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,007 reviews)
"Convenient location and comfortable room."
United States
Rogelio
The price is RM332
RM388 total
includes taxes & fees
8 Jun - 9 Jun
Americas Best Value Inn Medical Center Downtown

Golden Motel Near Houston Medical Center

Golden Motel Near Houston Medical Center
2.5 star property
South Central Houston
2.0 out of 10, (2 reviews)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
United States
Jacari
The price is RM260
RM330 total
includes taxes & fees
7 Jun - 8 Jun
Golden Motel Near Houston Medical Center

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (950 reviews)
"The hotel was clean, staff were friendly and the location was perfect for our event. I will definitely stay there again. "
United States
Ricardo
The price is RM577
RM675 total
includes taxes & fees
12 Jun - 13 Jun
Hilton University of Houston

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (574 reviews)
"We felt welcome from the moment we walked in. The owners are so hospitable and the place such a delight. Loved the generous breakfast and ambiance- great parking as well!"
United States
Carolina
The price is RM868
RM1,016 total
includes taxes & fees
6 Jun - 7 Jun
La Maison in Midtown an urban B&B

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,014 reviews)
"Perfect place for my family and I to stay when one of us has an appointment at MD Anderson. Super affordable and extremely close to the appointment locations. Stayed there 4 times with out any issues."
United States
Catherine
The price is RM338
RM397 total
includes taxes & fees
5 Jun - 6 Jun
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
3.0 star property
South Central Houston
9.8 out of 10, Exceptional, (76 reviews)
"Solo trip and it was a perfect location staff was nice and it was nice and clean!! Would stay there again. "
United States
Sharon
The price is RM785
RM919 total
includes taxes & fees
7 Jun - 8 Jun
Wanderstay Boutique Hotel

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (213 reviews)
"Neat place. They had snacks available and also helped with our bags."
United States
David
The price is RM821
RM1,020 total
includes taxes & fees
8 Jun - 9 Jun
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Hideaway Near Downtown Attractions

Houston Hideaway Near Downtown Attractions
2.0 star property
South Central Houston
The price is RM236
RM1,977 total
includes taxes & fees
8 Jun - 9 Jun
Houston Hideaway Near Downtown Attractions

Cozy 2BR Near NRG & Downtown FIFA World Cup

Cozy 2BR Near NRG & Downtown FIFA World Cup
3.0 star property
South Central Houston
The price is RM426
RM1,162 total
includes taxes & fees
8 Jun - 9 Jun
Cozy 2BR Near NRG & Downtown FIFA World Cup

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (238 reviews)
"I enjoyed my stay at this hotel."
United States
Tamela
The price is RM409
RM478 total
includes taxes & fees
5 Jun - 6 Jun
Southmore Boulevard Motel

Luxury Med Center Fully Equipped King Sized Bed Condos

Luxury Med Center Fully Equipped King Sized Bed Condos
4.0 star property
South Central Houston
8.4 out of 10, Very good, (92 reviews)
"Facility was nice. DRIFTRS, the management company, is really bad. We were there for 4 days. Upon arrival we noticed no toilet paper and half the light bulbs burned out. The place was so dark I needed a flashlight to use the kitchen. We reported these issues immediately. They told us to use kitchen paper towels as toilet paper and did not respond to all the burned out light bulbs. We woke up every morning with the apartment hot and stuffy. The NEST thermostat is programmed to continually...
United States
Gordon
The price is RM558
RM1,033 total
includes taxes & fees
30 Jun - 1 Jul
Luxury Med Center Fully Equipped King Sized Bed Condos

MorningSide Inn

MorningSide Inn
2.0 star property
South Central Houston
6.0 out of 10, (514 reviews)
"There is no coffeemaker anywhere no schuttel. This place should be razed ."
United States
Barbara
The price is RM519
RM608 total
includes taxes & fees
6 Jun - 7 Jun
MorningSide Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in South Central Houston

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Reception
Wanderstay Boutique Hotel
3.0 star property
9.8
Exceptional
76 reviews
View
Exterior
La Maison in Midtown an urban B&B
3.5 star property
9.8
Exceptional
574 reviews
View
Laptop workspace, blackout curtains, soundproofing, iron/ironing board
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
158 reviews
View
Outdoor pool, free pool cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District
4.0 star property
9.2
Wonderful
1,157 reviews
View
Premium bedding, pillow-top beds, minibar, in-room safe
Hotel Zaza Houston Museum District
4.5 star property
9.2
Wonderful
1,011 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Find out more about South Central Houston

Top reasons to visit South Central Houston

  • Cultural Richness: South Central Houston is home to numerous museums and fine arts venues, providing a deep dive into the area's vibrant cultural heritage.
  • Historic Institutions: Explore historic colleges and universities that reflect the educational legacy of the region.
  • Vibrant Music Scene: Attend lively music concerts that showcase local talent and the energetic spirit of Houston.
  • Diverse Shopping Experiences: Indulge in shopping at local centres, offering unique finds and souvenirs.
  • Inclusive Accommodations: Enjoy a range of comfortable, pet-friendly, and LGBTQIA welcoming hotels for a pleasant stay.

Find great hotels near South Central Houston

Discover a range of comfortable accommodations in South Central Houston, ideal for both leisure and business travellers. With options such as hotels and aparthotels, you'll find amenities like free breakfast and spacious layouts with dual sinks. Many establishments pride themselves on being pet-friendly and LGBTQIA welcoming, ensuring an inclusive and enjoyable experience for all guests. Explore the perfect base for your Houston adventure.

  • Club Quarters Hotel Downtown, Houston: This vibrant 4-star hotel is an ideal choice for business travellers and pet owners alike, situated 3.2km from South Central Houston. Club Quarters Hotel Downtown combines a contemporary atmosphere with convenient amenities, including a pet-friendly policy that welcomes dogs with special provisions like food and water bowls. Located in a bustling shopping district, it offers easy access to a plethora of retail options and dining establishments, making it perfect for those looking to blend work with leisure.
  • DoubleTree by Hilton Hotel & Suites Houston by the Galleria: Just 9.7km from South Central Houston, this 4-star hotel is tailored for families and business travellers seeking a shopping getaway. The DoubleTree by Hilton prides itself on its family-friendly amenities, including window guards and cribs for younger guests, ensuring a safe and comfortable stay. Guests can enjoy warm hospitality, highlighted by their signature chocolate chip cookies upon arrival, while being surrounded by a vibrant shopping atmosphere that caters to all ages and preferences.
  • The Royal Sonesta Houston Galleria: A sophisticated 4-star accommodation located 9.7km from South Central Houston, The Royal Sonesta is perfect for both business and leisure travellers. This pet-friendly establishment offers varied amenities with some restrictions for pets, ensuring a welcoming environment for all guests. Situated in a lively shopping district, visitors can easily explore an array of shops and restaurants, while the hotel's elegant interiors and attentive service create a luxurious and comfortable retreat.

Where to stay near South Central Houston

South Central Houston offers a vibrant blend of culture, history, and urban charm, making it an ideal destination for travellers. Explore the bustling business district, delve into the rich heritage of the American South, and experience the lively atmosphere of nearby areas like South Houston. Whether you're seeking family-friendly activities or cultural excursions, you'll find plenty to enjoy in this dynamic region of Houston.

  • Houston: As a bustling metropolis, Houston serves as the heart of South Central Houston. This diverse city attracts visitors year-round, with peak seasons in March, May, and July. Travellers flock to Houston for family-friendly, business, and city-themed experiences. Popular activities include shopping at expansive malls and attending lively music concerts. Notable landmarks such as sports stadiums and convention centres are easily accessible, making it an ideal base for exploration and excitement.
  • Downtown Houston: Located a mere 3.2km from South Central Houston, Downtown Houston is a vibrant neighbourhood that offers a blend of family, business, and entertainment experiences. With visitor numbers peaking in April and during the summer months, this area is alive with activities. People can enjoy shopping at various centres and catch a thrilling music concert. The proximity to key landmarks, including sports facilities and conference venues, enhances the travel experience, allowing for easy access to major events and attractions.
  • Houston Museum District: Just 1.6km away from South Central Houston, the Houston Museum District is a cultural gem that draws visitors for family outings, city exploration, and business-related trips. The peak visitation periods occur in March and from June to July, inviting guests to delve into educational experiences and enjoy local theatres. The area is home to a plethora of museums and research facilities, as well as modern universities, ensuring that there’s always something to discover in this intellectually stimulating neighbourhood.

Things to do near South Central Houston

South Central Houston offers an enriching blend of business, culture, and urban experiences. Visitors can explore various museums, attend vibrant music concerts, and indulge in shopping at local centres. For those interested in the arts, the area boasts fine arts venues and hosts numerous events throughout the year, ensuring a captivating experience for all. Whether you're seeking educational pursuits or leisurely activities, South Central Houston provides a diverse array of options.

Shopping

In South Central Houston, indulge in retail therapy at The Galleria, a vibrant shopping mall located 9.7km away, offering a mix of luxury and entertainment. Alternatively, visit the River Oaks District, 8.0km away, for a charming market experience, or explore the Shops at Houston Center, just 3.2km away, for family-friendly shopping.

Recreation

NRG Stadium, located 6.4km from South Central Houston, offers an energising atmosphere with various sports events. Nearby, Toyota Center, just 3.2km away, hosts exciting concerts and sports, while Daikin Park, also 3.2km distant, provides a lovely green space for relaxation and leisure activities.

Adventure

Experience the thrill of tennis at Homer Ford Tennis Center, located 3.2km from South Central Houston, where the vibrant atmosphere energises your game. For an adrenaline rush, try indoor skydiving at iFLY Indoor Skydiving, 16.1km away, or enjoy more tennis at Memorial Park Tennis Center, 9.7km out.

Nightlife

Experience the vibrant nightlife in South Central Houston by visiting the Bayou Music Center for captivating performances, or enjoy the intimate atmosphere at the Music Box Theater. For a lively night out, head to Bayou Place nightclub, where the city's energy and romance blend seamlessly.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for South Central Houston

For a budget-friendly visit to South Central Houston, consider travelling between November and January when prices are lower, particularly on Sundays. Use Expedia’s search tool to find affordable accommodation by sorting results from lowest to highest price and filtering for eco-friendly options. Additionally, maximise savings by booking a package that combines flights, hotel stays, and activities. For transport, utilise public buses and light rail, which are economical ways to explore the area, and take advantage of free local attractions to enhance your experience without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around South Central Houston are November to January, where the prices are slightly lower. This is in comparison to March to May, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around South Central Houston is Sunday. The most expensive day to stay around South Central Houston is Saturday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to specify your budget, desired location, and additional preferences. You can organise your results to display prices from lowest to highest, ensuring that the most affordable hotels appear at the top. Furthermore, you have the option to refine your search by hotel category; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels that you can book.
  • Consider bundling your trip: You can save money by combining your hotel accommodation in South Central Houston with your flights and activities by reserving an Expedia package.

Find the best attractions in and around South Central Houston

South Central Houston offers a delightful blend of business, cultural, and city-themed experiences. Visitors can explore historic colleges and universities, attend events at various conference venues, and appreciate art at local museums. This vibrant area caters to families and culture enthusiasts alike, providing a rich city experience filled with diverse attractions that reflect the unique spirit of Houston.

  • George R. Brown Convention Center: This expansive event venue, located 3.2km from South Central Houston, buzzes with business energy. Hosting various conferences and exhibitions, it’s a hub for networking and innovation, making it a lively destination for professionals and visitors alike.
  • St. Paul's United Methodist Church: Nestled in South Central Houston, this historic church radiates cultural vibes. Its stunning architecture and welcoming atmosphere provide a serene space for reflection and community gatherings, showcasing the rich heritage of the area.
  • Rice University: Located within South Central Houston, Rice University blends modernity with tradition. Its beautiful campus and vibrant student life offer a unique urban experience, making it an ideal spot for leisurely strolls and cultural events.

Best time to go to South Central Houston

The best time to visit South Central Houston can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around South Central Houston falls in August, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around South Central Houston falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January54.1°F (12.3°C)Light RainMostly SunnySlightly LowSlightly Low
February57.0°F (13.9°C)Light RainMostly CloudySlightly LowAverage
March63.9°F (17.7°C)Light RainMostly SunnySlightly HighSlightly High
April69.6°F (20.9°C)Light RainMostly SunnyAverageSlightly High
May76.6°F (24.8°C)Light RainMostly SunnySlightly HighSlightly High
June82.8°F (28.2°C)Light RainMostly SunnyAverageAverage
July84.2°F (29.0°C)Light RainMostly SunnySlightly HighAverage
August84.9°F (29.4°C)Light RainMostly SunnyAverageAverage
September80.6°F (27.0°C)Light RainMostly SunnyAverageAverage
October72.7°F (22.6°C)Light RainMostly SunnyAverageAverage
November62.8°F (17.1°C)Light RainMostly SunnyAverageSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to South Central Houston

Accessing South Central HOUston is convenient with three major airports. William P. Hobby Airport (HOU) is situated 11.3km away, with nearby hotels such as The Laura Hotel, Houston Downtown, and The Whitehall Houston, all approximately 14.5km from the airport. George Bush Intercontinental Airport (IAH), located 29.0km from South Central, offers options like the Sonesta Hotel and Houston Airport Marriott, which provide various transportation services. Ellington Field (EFD) is 22.5km away, with hotels including the Houston Marriott South at Hobby Airport and Hilton Houston NASA Clear Lake, ensuring comfortable stays close to your flight.

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighbourhood.
What's the best accommodation in South Central Houston?
Based on our traveller data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and Sentral Forme Houston.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1197 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Bagby Dog Park. Houston Zoo and Fertitta Center are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

Explore a world of travel with Expedia