Southeast Jacksonville Beach Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to RM 3,900 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

13733 Beach Blvd Jacksonville FL
  • 4 min drive from Mayo Clinic Florida
Stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

4660 Salisbury Road Jacksonville FL
  • 10 min drive from Mayo Clinic Florida
Stay at this business-friendly hotel in Jacksonville. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Wyndham Garden Jacksonville
Delta Hotels by Marriott™ Jacksonville Deerwood

Delta Hotels by Marriott™ Jacksonville Deerwood

4700 Salisbury Rd Jacksonville FL
  • 10 min drive from Mayo Clinic Florida
Stay at this business-friendly hotel in Jacksonville. Enjoy breakfast (surcharge), a free local area shuttle and room service. Our guests praise the helpful ...
Delta Hotels by Marriott™ Jacksonville Deerwood
See all 605 properties in Southeast Jacksonville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

St. Augustine: St. Johns River Airboat Safari with a Guide

St. Augustine: St. Johns River Airboat Safari with a Guide

RM210
per adult
100% of travellers recommend
St. Augustine: St. Johns River Airboat Safari with a Guide
Half-Day City Tour in Downtown Jacksonville

Half-Day City Tour in Downtown Jacksonville

RM459
per adult
100% of travellers recommend
Half-Day City Tour in Downtown Jacksonville
Amelia Island Floating Tiki Boat Cruise with BYOB Option

Amelia Island Floating Tiki Boat Cruise with BYOB Option

RM346
per adult
100% of travellers recommend
Amelia Island Floating Tiki Boat Cruise with BYOB Option
See all activities in Southeast Jacksonville
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.