Best Luxury Hotels in St. Charles

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles Luxury Hotels

Our top choices for St. Charles luxury hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,008 reviews)
  • cleanliness
    Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
The price is RM649
RM826 total
includes taxes & fees
1 Jul - 2 Jul
Ameristar Casino Resort and Spa

The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
9.0 out of 10, Wonderful, (146 reviews)
The price is RM521
RM594 total
includes taxes & fees
15 Jun - 16 Jun
The Inn at Elijah McLeans

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,611 reviews)
The price is RM391
RM514 total
includes taxes & fees
14 Jun - 15 Jun
River City Casino & Hotel

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,013 reviews)
The price is RM548
RM651 total
includes taxes & fees
28 Jun - 29 Jun
Drury Plaza Hotel St. Louis Brentwood

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,004 reviews)
  • cleanliness
    Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
The price is RM1,431
RM1,673 total
includes taxes & fees
18 Jun - 19 Jun
Four Seasons Hotel St Louis

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,967 reviews)
  • cleanliness
    Boutique retreat blends urban charm with luxury, from rooftop views to Egyptian cotton and rainfall showers.
The price is RM527
RM627 total
includes taxes & fees
29 Jun - 30 Jun
Moonrise Hotel

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,115 reviews)
The price is RM688
RM812 total
includes taxes & fees
14 Jun - 15 Jun
Hyatt Regency St. Louis at The Arch

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,010 reviews)
  • cleanliness
    Experience grandeur in a historic hotel with 7 restaurants, seasonal pool, and concierge services in city centre St. Louis.
The price is RM666
RM792 total
includes taxes & fees
20 Jun - 21 Jun
St. Louis Union Station Hotel, Curio Collection by Hilton

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,214 reviews)
The price is RM648
RM770 total
includes taxes & fees
21 Jun - 22 Jun
Live by Loews - St.Louis

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,296 reviews)
  • cleanliness
    Historic city centre St. Louis hotel offers elegant luxury in a preserved baroque setting.
The price is RM566
RM673 total
includes taxes & fees
28 Jun - 29 Jun
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Charles Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.

Explore a world of travel with Expedia