𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Southern Illinois from RM245 (2026) - Fully Refundable Options

A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Go beyond your typical stay in Southern Illinois

Spa

Waterpark

Family friendly

Hot tub

Cottage

Apartment

Pool

Pet friendly

Condo

Check prices for these dates

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Our top choices for Southern Illinois hotels

Spa

Cabin

Pet friendly

Breakfast included

Motel

Desk, blackout curtains, iron/ironing board, free cots/infant beds

1. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Rachid

RM454

RM512 total

includes taxes & fees

30 Aug - 31 Aug

2. Holiday Inn Express & Suites Mount Vernon by IHG

Mount Vernon

Angela D

RM483

RM544 total

includes taxes & fees

16 Aug - 17 Aug

3. Comfort Suites Mount Vernon

Mount Vernon

Erica

RM481

RM542 total

includes taxes & fees

16 Aug - 17 Aug

Pillow-top beds, in-room safe, desk, iron/ironing board

4. DoubleTree by Hilton Mt. Vernon

Mount Vernon

Samuel

RM523

RM589 total

includes taxes & fees

3 Sept - 4 Sept

Desk, blackout curtains, iron/ironing board, free WiFi

5. Super 8 by Wyndham Mt. Vernon IL

Mount Vernon

Matthew W,

RM276

RM315 total

includes taxes & fees

30 Aug - 31 Aug

Premium bedding, pillow-top beds, desk, laptop workspace

6. SureStay Hotel by Best Western Whittington Rend Lake

Whittington

Debbie

RM327

RM363 total

includes taxes & fees

12 Aug - 13 Aug

Blackout curtains, iron/ironing board, rollaway beds, free WiFi

7. Quality Inn Mount Vernon, IL

Mount Vernon

David

RM309

RM351 total

includes taxes & fees

23 Aug - 24 Aug

Pillow-top beds, desk, iron/ironing board, cots/infant beds

Indoor pool, open 8 AM to 10 PM, pool loungers

8. Best Western Plus Centralia Hotel & Suites

Centralia

Corey

RM610

RM683 total

includes taxes & fees

12 Aug - 13 Aug

9. Days Inn by Wyndham Mount Vernon

Mount Vernon

Norberto

RM296

RM336 total

includes taxes & fees

13 Aug - 14 Aug

10. Best Western U. S. Inn

Nashville

James

RM491

RM535 total

includes taxes & fees

16 Aug - 17 Aug

11. Drury Inn & Suites Marion

Marion

Alicia

RM434

RM520 total

includes taxes & fees

16 Aug - 17 Aug

Premium bedding, down duvets, desk, blackout curtains

12. Holiday Inn Express & Suites Effingham by IHG

Effingham

Sheridan

RM466

RM522 total

includes taxes & fees

23 Aug - 24 Aug

13. Comfort Inn & Suites Marion I-57

Marion

Kim

RM466

RM560 total

includes taxes & fees

16 Aug - 17 Aug

14. Hampton Inn & Suites Effingham

Effingham

Kate

RM500

RM555 total

includes taxes & fees

6 Sept - 7 Sept

Indoor pool, open 6:00 AM to 11:00 PM, pool loungers

Desk, laptop workspace, blackout curtains, iron/ironing board

15. La Quinta Inn & Suites by Wyndham Effingham

Effingham

Alexis

RM421

RM471 total

includes taxes & fees

23 Aug - 24 Aug

Indoor pool, open 7:00 AM to noon, pool loungers

16. Holiday Inn Effingham by IHG

Effingham

Parry

RM413

RM463 total

includes taxes & fees

31 Aug - 1 Sept

17. Cobblestone Inn & Suites - Altamont

Altamont

Daria

RM405

RM437 total

includes taxes & fees

12 Aug - 13 Aug

18. Best Western Plus Parkside Inn & Suites

Olney

Brenda

RM518

RM575 total

includes taxes & fees

19 Aug - 20 Aug

In-room safe, blackout curtains, iron/ironing board, free WiFi

19. The Principal Hotel

Columbia

Daniel

RM461

RM512 total

includes taxes & fees

12 Aug - 13 Aug

Hypo-allergenic bedding, in-room safe, desk, laptop workspace

20. Best Western Delta Inn

Effingham

Roger

RM362

RM405 total

includes taxes & fees

23 Aug - 24 Aug

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Holiday Rentals in Southern Illinois

Cottage

Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg

"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."

Cottage

Illinois Vacation Rental Home: Pets Welcome

Palestine

Cottage

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Robinson

Cottage

Cozy Anna Home Near Southern Illinois Attractions!

Anna

"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."

Apartment

Murphysboro Retreat w/ Deck Near Kinkaid Lake!

Murphysboro

"This is a very clean and nice apartment within a very close drive to the Kinkaid boat launch. Easy to locate and can fit a car with a boat in tow no problem. This spot was also much more quiet than the campground or RV spots nearby. They have a great porch and a grill and we didn’t bring something for it which made me sad. "

Cottage

Beautiful Makanda Cabin in Shawnee National Forest

Makanda

"It was very peaceful and relaxing. "

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Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

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O'Fallon Family Sports Park

8.6/10 (137 reviews)

This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.

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World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Harrah's Metropolis

8.0/10 (310 reviews)

This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards programme to maximise your experience while enjoying Southern classics at the on-site restaurants.

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Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois

Top Southern Illinois Hotel Reviews

Baymont by Wyndham Effingham

8/10 Good

"Everyone I dealt with from front desk to maid service were friendly and professional. The halls smelled somewhat musty but the room was fine."

Holiday Inn Express Metropolis by IHG

10/10 Excellent

"Clean room, good breakfast "

The Principal Hotel

10/10 Excellent

"great stay. Have to have front desk adjust room temperature."

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent

"The hotel was clean and the rooms were comfortable. We had small children with us and were hoping to check-in early to get some nap time. They were able to get both joining rooms available for us! It was much appreciated. We also enjoyed the indoor pool and the fitness gym during our stay."

Baymont by Wyndham Marion

10/10 Excellent

"It was clean, quiet, and good parking."

Best Western St. Louis Fairview Heights

10/10 Excellent

"The front desk was very nice and helpful the hotel is being remolded but clean. Itwas clean and the Ac blow cold, the breakfast was good for a hotel with different items.Also was in a nice safe area , easy access to the interstate and stores and restaurants me and wife both said we would stay here again"

Comfort Suites Fairview Heights - St. Louis

8/10 Good

"Service was good. Rooms were as expected for the price. However, one room had a bad smell that I think was coming from the tub. Swimming pool was not good. Very cloudy water and smelled of algae. Overall not bad for the price."

More cheap stays in Southern Illinois