Downtown

Seneca


Popular places to visit


Top hotels in Downtown

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
The price is RM312 per night from 27 Dec to 28 Dec
RM312
RM368 total
27 Dec - 28 Dec
includes taxes & fees
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...
7.8/10 Good! (659 reviews)
Clean room w fridge and microwave Comfy bed

Reviewed on 15 Nov 2025

Quality Inn Seneca Clemson Area US-123
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
The price is RM260 per night from 30 Nov to 1 Dec
RM260
RM288 total
30 Nov - 1 Dec
includes taxes & fees
Stay at this business-friendly motel in Anderson. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,015 reviews)
Beautiful well clean and decorated room, the staff at the front desk was so sweet and welcoming, close to dinner and shopping, good quality for the price you pay, recommend.

Reviewed on 23 Nov 2025

Days Inn by Wyndham Anderson
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
The price is RM382 per night from 22 Dec to 23 Dec
RM382
RM425 total
22 Dec - 23 Dec
includes taxes & fees
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,004 reviews)
Perfect location for my weekend

Reviewed on 21 Nov 2025

Best Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
The price is RM386 per night from 24 Dec to 25 Dec
RM386
RM428 total
24 Dec - 25 Dec
includes taxes & fees
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,005 reviews)
Ease of checking in

Reviewed on 23 Nov 2025

Comfort Inn & Suites Clemson - University Area
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
Stay at this cottage in Clemson. Enjoy air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy Waterfront Park are ...
Wooded Cottage - 3 Mi to Clemson University
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
The price is RM698 per night from 24 Dec to 25 Dec
RM698
RM774 total
24 Dec - 25 Dec
includes taxes & fees
Stay at this hotel in Clemson. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in their reviews. ...
9.8/10 Exceptional! (727 reviews)
BEST hotel in all of Clemson!

Reviewed on 15 Nov 2025

The Shepherd Hotel Downtown Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown

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Keowee Plantation

While Keowee Plantation isn't home to many top sights, The Gauntlet and Seneca Historic District are some notable places to visit nearby.

Keowee Plantation
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Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like The Gauntlet and Seneca Historic District.

Indian Oaks
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Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Serenity Bay
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Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and World of Energy.

Pine Ridge Point


Downtown