A historic church with two towers and a large central dome, surrounded by parked cars and a street.

Best Luxury Hotels in Santiago

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Check availability on Santiago Luxury Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Santiago luxury hotels

A pool surrounded by palm trees and a tiled roof structure.

1. Hotel Gran David

Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (449 reviews)
"Great place to stay. I would stay there again."
United States
Roxani
The price is RM359
RM395 total
includes taxes & fees
6 Nov - 7 Nov
Hotel Gran David
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santiago Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Santiago holiday?
Amenities are important when you plan a holiday, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Santiago offers. During your visit, you might want to enjoy the restaurants which Santiago is known for.
When can I expect good weather in Santiago?
Planning for the weather is a good way to make your trip to Santiago relaxing and enjoyable, especially when you're splurging. The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santiago are October, August, June and November, with each month seeing an average of 447 mm of rainfall.
What's there to see and do in Santiago?
Experience Santiago with a stop at Catedral of Santiago Apostol, Omar Torrijos Herrera Stadium and Plaza Banconal. If you have extra time while you're in the area, you might want to stop by Parque Acuatico Italia Guadalupe Panama and Los Pozos Termales.