A modern building with a unique triangular roof and a central spire.

Hotels in Santa Lucia, Syracuse

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Check prices for these dates

This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

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Our top choices for Santa Lucia hotels

A woman in a black swimsuit sitting in a hot tub overlooking a beach with a clear sky and the sun shining.

1. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Wonderful property, excellent staff and the most amazing view from the apartment"
Australia
Anthony
The price is RM953
RM1,095 total
includes taxes & fees
11 Sept - 12 Sept
Re Dionisio Luxury Suites
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.

2. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (292 reviews)
"Lovely hotel in a great spot, very helpful staff."
Australia
Mandy
The price is RM919
RM1,058 total
includes taxes & fees
10 Sept - 11 Sept
Caportigia Boutique Hotel
A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.

3. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (692 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is RM425
RM485 total
includes taxes & fees
13 Sept - 14 Sept
Grande Albergo Alfeo
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.

4. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (285 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is RM346
RM395 total
includes taxes & fees
5 Oct - 6 Oct
Nostos rooms & Apartments
A terrace with white tables and chairs, white umbrellas, and a view of the sea.

5. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (131 reviews)
"Hidden gem! The staff was extremely welcoming and helpful throughout our visit. Can't beat a room that looks out over the water and is a short walk into town. Would highly recommend!"
United States
James
The price is RM1,013
RM1,161 total
includes taxes & fees
23 Sept - 24 Sept
Giuggiulena Villa
A room with a table and chairs, a view of a harbor with boats and buildings, and a clear sky.

6. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"Clean room and well located."
United Kingdom
Hanna
The price is RM467
RM551 total
includes taxes & fees
17 Sept - 18 Sept
Lakkios
A balcony with potted plants and a metal railing.

7. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is RM304
RM347 total
includes taxes & fees
8 Oct - 9 Oct
Piccolo Hotel Casa Mia
A balcony with wicker chairs and a glass table overlooking a marina with boats.

8. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (39 reviews)
"Beautiful accomodation, perfect location close to restauranys and attractions, clean room/all renovated with style, friendly personnel, nice view of the port"
Canada
Martine
The price is RM867
RM989 total
includes taxes & fees
5 Oct - 6 Oct
Fortaleza Charme House
A hotel room with a large bed, a chair, a small table, and a chandelier.

9. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (44 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is RM493
RM562 total
includes taxes & fees
13 Sept - 14 Sept
Hotel Palazzo Cavalieri
An open balcony with a table and chairs, potted plants, and a view of a building with balconies and windows.

10. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (17 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is RM618
RM705 total
includes taxes & fees
2 Oct - 3 Oct
Calafatari B&B
A balcony with a table set for two, a chair, and a view of a building with multiple windows and balconies.

11. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (89 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is RM359
RM409 total
includes taxes & fees
8 Oct - 9 Oct
B&B Nike
A hot tub with a view of a marina.

12. Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is RM881
RM1,017 total
includes taxes & fees
12 Sept - 13 Sept
Casa Miranda Boutique
A bedroom with a stone wall, a bed with a wooden headboard, a tray with a plant, and a window with curtains.

13. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is RM338
RM385 total
includes taxes & fees
11 Sept - 12 Sept
B&B Siracusa
A modern dining area with a white table, green chairs, and a potted plant.

14. San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (9 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is RM492
RM561 total
includes taxes & fees
4 Oct - 5 Oct
San Nicola Rooms Siracusa
A balcony with a table set for tea, a book, and a view of a building and water.

15. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is RM398
RM454 total
includes taxes & fees
2 Oct - 3 Oct
Hotel Mediterraneo
A marina with numerous boats docked, a clear sky, and a building with outdoor seating.

16. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is RM319
RM364 total
includes taxes & fees
1 Oct - 2 Oct
Regina Margherita
A modern bedroom with a bed, bedside table, and a unique feature of a table with a fire effect.

17. B&B IL MORO

B&B IL MORO
Santa Lucia
4.0 out of 10, (1 review)
"Personne sur place pour nous aider. La carte de la chambre était défectueuse dès l'arrivée. Par la suite l'électricité a manqué à 21h, nous avons du contacter les propriétaires via What's App dans le noir. Nous apprécions faire affaire avec des humains et non des applications impersonnelles et des vidéos. Le lit était petit et inconfortable. Pas d'oreiller d'extra ni de boîte de mouchoirs. Le quartier est lugubre."
Canada
Celine B. La
The price is RM362
RM413 total
includes taxes & fees
8 Oct - 9 Oct
B&B IL MORO
A modern hotel room with a bed, a bedside table, a decorative wall, and a shower area.

18. B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
6.8 out of 10, (3 reviews)
"Sehr gute Lage, aber das Mobiliar ist in extrem veralteten Zustand, Gestell des Bettes nicht fest, sehr wenig Platz, uralte, fleckige Matratze mit scharfen Federn, kein Internetzugang des WLANs und das Frühstück ist ein Witz. Für 1 Nacht gerade so in Ordnung, ansonsten nicht empfehlenswert."
Germany
Alessandra
The price is RM186
RM266 total
includes taxes & fees
12 Sept - 13 Sept
B&B L'INFIORESCENZA
A table with two wine glasses and a decorative item, viewed through a window overlooking a parking area with cars and greenery.

19. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is RM242
RM276 total
includes taxes & fees
3 Oct - 4 Oct
Gymnasium
A rooftop lounge area with lounge chairs and a large potted plant.

20. Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is RM249
RM391 total
includes taxes & fees
30 Sept - 1 Oct
Le Camere Luxsury Rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A terrace with white tables and chairs, white umbrellas, and a view of the sea.
Giuggiulena Villa
3.0 star property
10.0
Exceptional
131 reviews
View
An open balcony with a table and chairs, potted plants, and a view of a building with balconies and windows.
Calafatari B&B
3.0 star property
9.8
Exceptional
17 reviews
View
A room with a table and chairs, a view of a harbor with boats and buildings, and a clear sky.
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
A bedroom with a bed, a desk, a chair, a television, and a mirror.
Fortuna Guest House
1.0 star property
9.2
Wonderful
19 reviews
View
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
285 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Teatro dei Pupi or Cathedral of Syracuse.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Great location to explore the old town. Quality hotel and very attentive staff. Wouldn’t hesitate staying there again."
Neale 3-night trip
Posted 2 hours ago
Algila' Ortigia Charme Hotel

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.
How many hotels will I find in Santa Lucia?
Expedia has 314 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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