San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
La entrada a la Ciudad de Panamá
Edificio el tornillo

Popular places to visit

Things to do


Top hotels in San Francisco

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is RM523 per night from 8 Mar to 9 Mar
RM523
RM575 total
8 Mar - 9 Mar
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,001 reviews)
The bed was comfortable and the room quiet. We stayed 4 nights so it would have been nice if the tea and coffee had been replenished during our stay. Also some towels were not always provided ( bath mats, face cloths)

Reviewed on 17 Feb 2026

Sheraton Grand Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is RM673 per night from 25 Feb to 26 Feb
RM673
RM740 total
25 Feb - 26 Feb
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,037 reviews)
Tremendous views of the city from our 21st floor hotel room. Huge breakfast with large selection. The room was super comfortable and spacious. Loved the layout. The beds super comfortable The staff was excellent.

Reviewed on 18 Feb 2026

Las Americas Golden Tower Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is RM1,205 per night from 7 Mar to 8 Mar
RM1,205
RM1,326 total
7 Mar - 8 Mar
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,006 reviews)
The room was perfect

Reviewed on 17 Feb 2026

JW Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is RM461 per night from 14 Mar to 15 Mar
RM461
RM507 total
14 Mar - 15 Mar
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. ...
9/10 Wonderful! (1,002 reviews)
Location was great and so was the staff

Reviewed on 17 Feb 2026

Courtyard by Marriott Panama Multiplaza Mall
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
The price is RM452 per night from 20 Feb to 21 Feb
RM452
RM497 total
20 Feb - 21 Feb
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff in their ...
8.6/10 Excellent! (1,558 reviews)
Yes staff not supportive

Reviewed on 10 Feb 2026

Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is RM421 per night from 20 Feb to 21 Feb
RM421
RM463 total
20 Feb - 21 Feb
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool in their ...
9.4/10 Exceptional! (2,143 reviews)
Room and location are excellent. Everything was clean and nice. Staff were friendly. No issues at all. Thank you

Reviewed on 18 Feb 2026

Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Multiplaza Pacific Mall or Avenida Balboa.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Multicentro Panama and Avenida Balboa while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

Bella Vista
Aerial view of the city skyline of Panama City business district

Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Multicentro Panama or Avenida Balboa.

Marbella


San Francisco