San Francisco

Panama City

Photo by Hideki Yamagata
Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Nóra Széll
Photo by Panama Roadrunner
Photo by Panama Roadrunner

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

4.5/5(8 reviews)

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall

ATLAPA Conventions Center

Learn about the events happening in ATLAPA Conventions Center during your trip to Panama City. Stroll along the seaside in this vibrant area or visit its top-notch restaurants.

ATLAPA Conventions Center

Multicentro Panama

4/5(1 review)

During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.

Multicentro Panama

Pacific Center

You can browse for the perfect souvenirs at Pacific Center during your visit to Panama City. You can enjoy the restaurants while in the area.

Pacific Center

Panama Canal Murals

4/5(1 review)

You can learn about the history of Panama City with a stop at Panama Canal Murals. Stroll along the seaside in this vibrant area or visit its lively bars.

Panama Canal Murals

Hospital Punta Pacífica

If Hospital Punta Pacífica is what brings you to town, hopefully you'll have a chance to explore more of Panama City.

Hospital Punta Pacífica

Things to do

Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

RM634
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Boat tour in the Panama Canal to Monkeys and sloths islands

Boat tour in the Panama Canal to Monkeys and sloths islands

RM313
per adult
96% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
La casa de papel Day tour in San Blas Islands - All inclusive- No hidden fees.

All included - Day tour in San Blas Islands - No extra fees

RM464
per adult
All included - Day tour in San Blas Islands - No extra fees
Full-Day SAN BLAS ISLAND & Snorkeling Tour + Transport from Panama City

Full-Day SAN BLAS ISLAND Tour + Transport from Panama City

RM605
per adult
Full-Day SAN BLAS ISLAND Tour + Transport from Panama City
3-Hour Private Custom Tour with a Local Guide in Panama City

Panama City : Custom Walking Tour with A Guide (Private Tour)

RM257
per adult
Panama City : Custom Walking Tour with A Guide (Private Tour)
Live the Experience of a Full Day in San Blas

Live the Experience of a Full Day in San Blas

RM659
per adult
100% of travellers recommend
Live the Experience of a Full Day in San Blas
See all activities in Panama City

Top hotels in San Francisco

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
The price is RM530 per night from 28 Jul to 29 Jul
RM530
RM583 total
28 Jul - 29 Jul
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (904 reviews)
"Food was good but not excellent ,bedrooms clean but in the tired side"

Reviewed on 19 Jul 2025

Sheraton Grand Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is RM860 per night from 22 Aug to 23 Aug
RM860
RM946 total
22 Aug - 23 Aug
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,004 reviews)
JW Marriott Experience
"The hotel was spotless, and the staff were friendly. It's a bit expensive, as I was expecting more of a luxury hotel. The only bad thing was the breakfast one morning, when everything was cold and the cup of coffee wasn't hot. The toast was hard as a rock, so it was a total disappointment for the ..."

Reviewed on 18 Jul 2025

JW Marriott Panama
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
The price is RM469 per night from 29 Jul to 30 Jul
RM469
RM516 total
29 Jul - 30 Jul
includes taxes & fees
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,004 reviews)
"Nice Clean and Convenient"

Reviewed on 20 Jul 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
The price is RM538 per night from 2 Aug to 3 Aug
RM538
RM592 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (957 reviews)
"I would stay again. Was really nice"

Reviewed on 18 Jul 2025

Megapolis Hotel Panamá
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
The price is RM394 per night from 23 Jul to 24 Jul
RM394
RM434 total
23 Jul - 24 Jul
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,245 reviews)
"Great staff, very helpful. Super breakfast!! Will stay there again on my next visit"

Reviewed on 17 Jul 2025

Decapolis Hotel Panama City
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
The price is RM597 per night from 27 Jul to 28 Jul
RM597
RM657 total
27 Jul - 28 Jul
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,001 reviews)
"Clean and central"

Reviewed on 17 Jul 2025

Las Americas Golden Tower Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

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Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
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Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
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Pueblo Nuevo

While there might not be top attractions in Pueblo Nuevo, you can explore the larger area and discover places like El Dorado Mall and Multiplaza Pacific Mall.

Pueblo Nuevo
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El Cangrejo

4/5(5 area reviews)

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

El Cangrejo

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