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San Francisco hotels from RM259

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Check prices for these dates

Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov

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Our top choices for San Francisco hotels

A modern hotel with a prominent entrance, outdoor seating area, and a handicap-accessible parking space.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (606 reviews)
"The service is pretty stable."
United States
Yali
The price is RM327
RM360 total
includes taxes & fees
17 Nov - 18 Nov
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.

2. Hotel Gran David

Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (452 reviews)
"Everything was clean and organized. Some of the front desk staff was friendly . Breakfast was well prepared although I do feel that coffee refills should be free of charge when you have spent the night."
United States
Michelle
The price is RM324
RM356 total
includes taxes & fees
16 Nov - 17 Nov
Hotel Gran David
A swimming pool with a slide, surrounded by lush greenery and a gazebo.

3. HOTEL VISTA LAGO

HOTEL VISTA LAGO
3.0 star property
La Pena
9.4 out of 10, Exceptional, (128 reviews)
"We went to this hotel for the first time and itā€™s so amazing, excellent food nothing else to add"
United States
Christian
The price is RM313
RM344 total
includes taxes & fees
16 Nov - 17 Nov
HOTEL VISTA LAGO
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.

4. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
3.0 star property
Nuevo Santiago
8.8 out of 10, Excellent, (16 reviews)
"Clean room, present staff, and in a central Ć”rea. Doesnā€™t have hot water BTW"
United States
Alexandria
The price is RM235
RM259 total
includes taxes & fees
16 Nov - 17 Nov
Hotel Plaza Los Tucanes
A table set with plates, a vase with flowers, a bottle labeled "Miel," and a scenic mountain view in the background.

5. Hotel Anachoreo

Hotel Anachoreo
3.0 star property
Santa Fe
9.6 out of 10, Exceptional, (47 reviews)
"Beautiful property, great staff and delicious food!"
United States
Denise
The price is RM346
RM380 total
includes taxes & fees
16 Nov - 17 Nov
Hotel Anachoreo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Francisco Hotel Reviews

Hotel Gran David

Hotel Gran David

8/10 Good
"Everything was clean and organized. Some of the front desk staff was friendly . Breakfast was well prepared although I do feel that coffee refills should be free of charge when you have spent the night."
Michelle 2-night trip
Posted 2 days ago
Hotel Gran David

More cheap stays in San Francisco

La Qhia Eco Retreat

La Qhia Eco Retreat

Barriada el Cerro A 100 Mts De Santa Fe Veraguas
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8.2/10 Very good! (22 reviews)

Frequently asked questions

What's the best place for a stay in San Francisco?
Hotel Mykonos Panama, located 10.4 mi (16.8 km) from the heart of San Francisco, is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are Hotel Gran David and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in San Francisco.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in San Francisco.
What is staying in San Francisco like?
Visitors to San Francisco will definitely find plenty to explore and enjoy. There are 18 hotels and other accommodation options in the surrounding area. Find out more about San Francisco.
What should I see while I'm in San Francisco?
Places to visit in the wider area include Laguna de La Yeguada, Parque Acuatico Italia Guadalupe Panama and Catedral of Santiago Apostol. You'll also find Los Pozos Termales and Omar Torrijos Herrera Stadium in the area. Take a look at what more there is to see and do in Expedia's San Francisco guide.
What's the seasonal weather like in San Francisco?
The hottest months are usually March and April, with an average temperature of 27Ā°C, while the coldest months are January and December, with an average of 25Ā°C. The rainiest months in San Francisco are October, August, June and November, with each month seeing an average of 447 mm of rainfall.