A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

Puxico hotels

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Check prices for these dates

Tonight
15 Aug - 16 Aug
Tomorrow
16 Aug - 17 Aug
Next weekend
21 Aug - 23 Aug
In two weeks
28 Aug - 30 Aug

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Our top choices for Puxico hotels

1. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Arsenia
RM413
RM467 total
includes taxes & fees
23 Aug - 24 Aug
Fairfield Inn & Suites by Marriott Poplar Bluff

2. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Vanessa
RM399
RM448 total
includes taxes & fees
22 Aug - 23 Aug
Hampton Inn By Hilton Dexter

3. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Elaine
RM384
RM434 total
includes taxes & fees
23 Aug - 24 Aug
Drury Inn & Suites Poplar Bluff

4. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Philip
RM382
RM428 total
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn Poplar Bluff

5. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
United States
Steven
RM349
RM392 total
includes taxes & fees
20 Aug - 21 Aug
Travelodge by Wyndham Dexter

6. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Kathleen
RM294
RM329 total
includes taxes & fees
16 Aug - 17 Aug
Motel 6 Poplar Bluff, MO

7. Econo Lodge Dexter

Econo Lodge Dexter
Dexter
United States
Herman
RM208
RM234 total
includes taxes & fees
14 Sept - 15 Sept
Econo Lodge Dexter

8. Dexter Inn

Dexter Inn
Dexter
United States
Cynthia
RM266
RM298 total
includes taxes & fees
20 Aug - 21 Aug
Dexter Inn

9. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
ASHTON
RM343
RM388 total
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Poplar Bluff by IHG

10. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
Poplar Bluff
United States
Muhammad
RM334
RM377 total
includes taxes & fees
13 Sept - 14 Sept
Comfort Inn Poplar Bluff North

11. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
RM344
RM374 total
includes taxes & fees
12 Sept - 13 Sept
EC Reed's Mercantile and Hotel

12. Lake Wappapello

Lake Wappapello
Williamsville
United States
Tonya
RM313
RM330 total
includes taxes & fees
16 Aug - 17 Aug
Lake Wappapello

13. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
Poplar Bluff
United States
Diana
RM226
RM254 total
includes taxes & fees
14 Sept - 15 Sept
Super 8 by Wyndham Poplar Bluff Missouri

14. OYO Hickory House Inn

OYO Hickory House Inn
Dexter
United States
Tammy
RM185
RM227 total
includes taxes & fees
14 Sept - 15 Sept
OYO Hickory House Inn
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Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

See all hotels in Puxico
A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.
Photo by Mike McClain

Top Puxico Hotel Reviews

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

8/10 Good
"It wasnโ€™t bad. Iโ€™d stay there here."
Russ 1-night trip
Posted 2 days ago
Super 8 by Wyndham Poplar Bluff Missouri
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent
"Clean room help staff basic breakfast, but was good parking. Plenty easy to reach."
Warren 1-night trip
Posted 2 days ago
Fairfield Inn & Suites by Marriott Poplar Bluff
Lake Wappapello

Lake Wappapello

10/10 Excellent
"Great cabin! Better to book directly than with 3rd party, would have been cheaper."
Bobby 1-night trip
Posted 6 days ago
Lake Wappapello
Dexter Inn

Dexter Inn

10/10 Excellent
"Clean room clean bathroom and nice staff"
david 1-night trip
Posted 6 days ago
Dexter Inn
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

8/10 Good
"F"
Lori 2-night trip
Posted 8 days ago
Comfort Inn Poplar Bluff North
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent
"During summer time, donโ€™t park behind the building. Thereโ€™s a pond in the distance and the light draws a TON of mosquitoes there, but the other entrances are all fine. The pond makes for a beautiful view with ducks and cranes, though. Everything about the bed was heavenly. Send the whole thing to my house, pronto! LOL The supplied shower body gel, shampoo, conditioner, and body lotion by Zero% is to die for! Smells great, super moisturizing, and good for the planet? Wow! The free breakfast was awesome! Waffles and fresh oatmeal with a HUGE variety of toppings, cereal and milk, juices, coffees and teas with sweeteners, sugars, creams, and real honey, cocoa, yogurt, boiled eggs, scrambled eggs, bacon, sausage, ranch potatoes, bagels (soft!), muffins, scones, toast and all the spreads for them, fresh fruitโ€ฆ what more could you need FOR FREE? Love love love the packaged reusable/disposable coffee pod holder for the coffee maker in the room. No more worrying if it was cleaned, cleaned properly, or used to wash someoneโ€™s underwear beforehand. Water pressure, shower head, and temperature was just right. I wish the light would stay on during the shower, though. And even with the door barely ajar the light and fan was still kicking on when I wasnโ€™t in the bathroom. I was in the bed. Alone. Air conditioner/heater is a vast improvement from the old style in other hotels. It has a wall control just like home! The TV is giant! Anyway, will absolutely be back more than once. Thank you!"
Dawn 1-night trip
Posted 12 days ago
Hampton Inn By Hilton Dexter
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

8/10 Good
"Lean room. Very basic. Some sort of breakfast would had been nice. Overall is was good. Great price"
Kenneth 1-night trip
Posted 2 weeks ago
Travelodge by Wyndham Dexter
OYO Hickory House Inn

OYO Hickory House Inn

10/10 Excellent
"Nice for overnight stop"
Tammy 1-night trip
Posted 2 weeks ago
OYO Hickory House Inn
Econo Lodge Dexter

Econo Lodge Dexter

8/10 Good
"Carpet was stinky. Handrails were loose. Air conditioner was working, but was unreliable and hard to control. Froze us out first night, then had to keep adjusting it. Parking lot was cracked and had broken pipes. Price was very reasonable, but you get what you pay for."
randy 2-night trip
Posted 3 weeks ago
Econo Lodge Dexter

Frequently asked questions

What's the best place for a stay in Puxico?
Motel 6 Poplar Bluff, MO, located 19.4 mi (31.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Fairfield Inn & Suites by Marriott Poplar Bluff and Drury Inn & Suites Poplar Bluff. See all available top hotels, or vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
What is staying in Puxico like?
Travellers to Puxico will find plenty to explore and enjoy. There are 55 hotels and other accommodation options in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.
What's the seasonal weather in Puxico?
The hottest months are usually July and August, with an average temperature of 25ยฐC, while the coldest months are January and February, with an average of 5ยฐC. Average annual precipitation for Puxico is 1502 mm.

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