𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Puxico from RM234 (2026) - Fully Refundable Options

A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Puxico

Pet friendly

Apartment

Condo

Pool

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Puxico hotels

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

1. Hampton Inn By Hilton Dexter

Dexter

Kendall

RM399

RM448 total

includes taxes & fees

11 Oct - 12 Oct

A diner with booth seating, a checkered floor, and a counter with a cash register.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

2. Travelodge by Wyndham Dexter

Dexter

Steven

RM353

RM396 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A hotel with a brick facade, multiple windows, and a covered entrance area.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

3. Econo Lodge Dexter

Dexter

Herman

RM208

RM234 total

includes taxes & fees

1 Nov - 2 Nov

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

4. Hampton Inn Poplar Bluff

Poplar Bluff

Rhonda

RM371

RM416 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a reception desk, seating area, and large windows.

An indoor swimming pool with a clear view of the outside through large windows.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

5. Drury Inn & Suites Poplar Bluff

Poplar Bluff

Dean

RM384

RM434 total

includes taxes & fees

29 Oct - 30 Oct

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

6. Dexter Inn

Dexter

Edward

RM282

RM316 total

includes taxes & fees

4 Oct - 5 Oct

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

A corner market with a refrigerated display case and a pantry area.

7. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

Vicki

RM413

RM467 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A motel with a prominent '66' sign, large windows, and a flat roof.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.

8. Motel 6 Poplar Bluff, MO

Poplar Bluff

Cindy

RM323

RM361 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.

A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.

A bathroom with a bathtub, toilet, and a shower curtain.

9. OYO Hickory House Inn

Dexter

DIEGO

RM225

RM275 total

includes taxes & fees

17 Oct - 18 Oct

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.

10. Holiday Inn Poplar Bluff by IHG

Poplar Bluff

Nathan

RM331

RM374 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel lobby with a coffee station, seating area, and a television screen.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel room with a bed, a sofa, a small table, and a painting on the wall.

11. Comfort Inn Poplar Bluff North

Poplar Bluff

Muhammad

RM306

RM345 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A laundry area with two stacked washers and dryers, a control panel, and a beige wall with a wooden panel above the dryers.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A two-story motel with a covered parking area and a bench outside.

12. Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

Diana

RM274

RM310 total

includes taxes & fees

10 Oct - 11 Oct

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

A bedroom with a wooden bed, a bench, and a window.

A calm lake with a wooden dock and a forested island in the distance.

13. Lake Wappapello

Williamsville

Tonya

RM368

RM388 total

includes taxes & fees

9 Oct - 10 Oct

A living room with a blue wall, a fireplace, a sofa, and a chair.

A bar area with stools and a counter where a bartender is serving drinks.

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

14. EC Reed's Mercantile and Hotel

Marble Hill

JANEEN

RM429

RM467 total

includes taxes & fees

4 Oct - 5 Oct

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

A house with a red door, a porch with rocking chairs, and a wreath on the door.

A two-story house with a deck and a covered porch.

A spacious dining area with a stone wall, wooden furniture, and a fireplace.

15. 40-acre Poplar Bluff Nature Lovers Paradise!

Poplar Bluff

Anonymous traveller

RM490

RM1,213 total

includes taxes & fees

7 Oct - 8 Oct

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

See all hotels in Puxico

Top Puxico Hotel Reviews

Holiday Inn Poplar Bluff by IHG

10/10 Excellent

"Debbie at the front desk is perfect."

Motel 6 Poplar Bluff, MO

10/10 Excellent

"Terrific base accommodation. Clean, efficient. I use this place whenever I’m in the area. I’m"

EC Reed's Mercantile and Hotel

8/10 Good

"Very cute and clean room. The hotel was quaint, but the lay out was a little strange. Everything was ready and convenient for us when we arrived to check-in. The process was just as easy to check-out. Never had to communicate anything to staff. It was a contract-less transaction. But very clear if any thing was needed that were able to contact someone for immediate assistance. I actually loved the quaintness. The only thing that was an issue, were the doors need adjusting because they would stick and they were hard to pull open. I would definitely stay there again. Even with the hard to open doors."

Lake Wappapello

10/10 Excellent

"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from the park. We ordered deli sandwiches from here and picked up some icecream. The sandwiches were delicious and the store had pretty much whatever you might need. The checkin process was great with good communication about which cabin to go to, what the door code was etc... We plan to come back for a longer stay so we can have another evening around the firepit and see all of the stars. Great place to stay."

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO

RM274

RM310 total

10 Oct - 11 Oct

includes taxes & fees

Dexter Inn

1807 W Business US Highway 60 Dexter MO

RM282

RM316 total

4 Oct - 5 Oct

includes taxes & fees

Comfort Inn Poplar Bluff North

2582 N Westwood Blvd Poplar Bluff MO

RM306

RM345 total

1 Nov - 2 Nov

includes taxes & fees

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

RM323

RM361 total

4 Oct - 5 Oct

includes taxes & fees

8/10 Very good! (1,004 reviews)

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO

RM371

RM416 total

18 Oct - 19 Oct

includes taxes & fees

Hampton Inn By Hilton Dexter

2179 Gill Plaza Drive Dexter MO

RM399

RM448 total

11 Oct - 12 Oct

includes taxes & fees

Frequently asked questions

What's the best place for a stay in Puxico?

Holiday Inn Poplar Bluff by IHG, located 18.8 mi (30.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Hampton Inn Poplar Bluff and Motel 6 Poplar Bluff, MO. See all available top hotels, or vacation rentals in Puxico.

If I need to cancel my hotel reservation in Puxico, will I receive a refund?

Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.

What is staying in Puxico like?

Travellers to Puxico will find plenty to explore and enjoy. There are 52 hotels and other accommodation options in the surrounding area. Find out more about Puxico.

What is there to see in Puxico?

A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.

What's the seasonal weather in Puxico?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Puxico is 1502 mm.

Puxico hotels from RM234

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Puxico

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Puxico hotels

1. Hampton Inn By Hilton Dexter

2. Travelodge by Wyndham Dexter

3. Econo Lodge Dexter

4. Hampton Inn Poplar Bluff

5. Drury Inn & Suites Poplar Bluff

6. Dexter Inn

7. Fairfield Inn & Suites by Marriott Poplar Bluff

8. Motel 6 Poplar Bluff, MO

9. OYO Hickory House Inn

10. Holiday Inn Poplar Bluff by IHG

11. Comfort Inn Poplar Bluff North

12. Super 8 by Wyndham Poplar Bluff Missouri

13. Lake Wappapello

14. EC Reed's Mercantile and Hotel

15. 40-acre Poplar Bluff Nature Lovers Paradise!

Learn more about Puxico

Top Puxico Hotel Reviews

Holiday Inn Poplar Bluff by IHG

Motel 6 Poplar Bluff, MO

EC Reed's Mercantile and Hotel

Lake Wappapello

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

Dexter Inn

Comfort Inn Poplar Bluff North

Motel 6 Poplar Bluff, MO

Hampton Inn Poplar Bluff

Hampton Inn By Hilton Dexter

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app