A densely packed urban area with numerous buildings and a prominent tower on a hill.

Hotels in Puerto Santa Ana, Guayaquil

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Check prices for these dates

This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

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Our top choices for Puerto Santa Ana hotels

A modern bar area with a bar counter, seating, and a large window.

1. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (1,007 reviews)
"Great hotel to stay in! Staff was super friendly!"
United States
Isabel
The price is RM466
RM523 total
13 Sept - 14 Sept
Wyndham Guayaquil Puerto Santa Ana
A rooftop pool with a view of the city skyline.

2. Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (109 reviews)
"So clean and very nice people. I really recommend this facility, nice environment. My next trip lm booking in this apartment"
United States
Pedro
The price is RM346
RM350 total
23 Sept - 24 Sept
Luxury Suites Riverfront GYE
A rooftop terrace with outdoor seating, a pool, and a city view at sunset.

3. River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (63 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is RM433
RM437 total
8 Sept - 9 Sept
River View suites Puerto Santa Ana gye
A grand room with ornate chandeliers, a large sofa, a round armchair, and a fireplace.

4. Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (147 reviews)
"Great place historical. Good service n breakfast. Great location"
United States
Mary Grant
The price is RM240
RM268 total
8 Sept - 9 Sept
Mansión del Río
A bathroom with a bathtub, a stone wall, a window with a view, and a table with chairs.

5. Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (5 reviews)
"Outstanding staff - great property"
United States
septimiu
The price is RM1,359
RM1,512 total
8 Sept - 9 Sept
Hotel Río Guayas by Art Hotels Ecuador
A person in a swimsuit and red hat sitting on a green inflatable ring in a pool.

6. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,002 reviews)
"Very nice stay"
United States
Freddy
The price is RM372
RM419 total
18 Sept - 19 Sept
Oro Verde Guayaquil
A hotel lobby with a modern design, featuring a reception desk, seating area, and decorative columns.

7. Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 1.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (950 reviews)
"There’s a restaurant downstairs. Try the Encocado de camarón. Best food ever!"
United States
Marlaynna
The price is RM262
RM294 total
12 Sept - 13 Sept
Hotel Palace Guayaquil
An aerial view of a hotel with a swimming pool surrounded by lush greenery and a decorative garden.

8. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Pool is surrounded by the dining area, it made it more a chill space than lounge. The hotel great service, very accommodating and noticeable security around the premises"
United States
tahiane
The price is RM304
RM341 total
3 Oct - 4 Oct
Grand Hotel Guayaquil, Centro Histórico.
A buffet setup with various food items, a modern chandelier, and a patterned floor.

9. Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (337 reviews)
"Great location."
United States
George S
The price is RM255
RM286 total
12 Sept - 13 Sept
Ibis Styles El Malecon Guayaquil
An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

10. Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
8.0 out of 10, Very good, (410 reviews)
"Love the area where the hotel is located. Excellent breakfast. The pool area is beautiful where you can seat and relax "
United States
Sixto
The price is RM255
RM259 total
8 Sept - 9 Sept
Hotel Ramada
A modern hotel lobby with a reception desk, seating area, and a large decorative plant.

11. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,001 reviews)
"Good staff, excelent food. I will defenetly will come back"
United States
Gloria E
The price is RM324
RM362 total
11 Sept - 12 Sept
Courtyard by Marriott Guayaquil
A modern bar area with a bar counter, stools, and a seating area with a table and chairs.

12. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,005 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is RM324
RM362 total
13 Sept - 14 Sept
Wyndham Garden Guayaquil
A modern lobby with large windows, a staircase, and comfortable seating areas.

13. Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (125 reviews)
"Good staff...great location"
United States
ALBERTO
The price is RM298
RM382 total
2 Oct - 3 Oct
Doubletree By Hilton Guayaquil
A cocktail on a marble table with a pool in the background.

14. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 1.4 km from Puerto Santa Ana
8.4 out of 10, Very good, (164 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is RM179
RM183 total
8 Sept - 9 Sept
Hotel Patrimonial by Greenfield
A room with a hammock, striped sofas, a stone floor, and a ceiling fan.

15. NCG SUITE ATARAZANA

NCG SUITE ATARAZANA
2.0 star property
La Atarazana, 0.8 km from Puerto Santa Ana
The price is RM162
RM162 total
8 Sept - 9 Sept
NCG SUITE ATARAZANA
A breakfast table with various foods and a view of a park through a window.

16. Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,012 reviews)
"Excellent hotel"
United States
Monica
The price is RM288
RM327 total
26 Sept - 27 Sept
Unipark by Oro Verde Hotels
An outdoor patio with wicker furniture, a stone wall, and a water feature.

17. Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 2.7 km from Puerto Santa Ana
8.4 out of 10, Very good, (255 reviews)
"👍"
United States
Marcos
The price is RM263
RM293 total
8 Sept - 9 Sept
Hotel Marcelius
An outdoor cafe with tables and chairs, surrounded by trees and buildings.

18. Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
7.6 out of 10, Good, (9 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is RM200
RM204 total
8 Sept - 9 Sept
Fortune Hotel
A modern interior with a seating area, a kitchen, and a dining space.

19. Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,009 reviews)
"Loved the closeness to Guayaquil airport, the staff was amazing, will definitely stay there again."
United States
Giovanna
The price is RM392
RM442 total
26 Sept - 27 Sept
Holiday Inn Guayaquil Airport by IHG
A reception desk with a marble top and a modern light fixture above it.

20. TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,009 reviews)
"Great place to stay near the airport and just steps from Mall del Sol"
United States
Carlos
The price is RM342
RM386 total
13 Sept - 14 Sept
TRYP by Wyndham Guayaquil Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Moorish Clock Tower while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

A golden statue of two figures forming a heart shape on a paved area with a modern building in the background.
Photo by Botak Jon
Open Photo by Botak Jon

Simón Bolívar

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and San Marino Mall, some noteworthy sights in the nearby area.

Top Puerto Santa Ana Hotel Reviews

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport

10/10 Excellent
"The staff was wonderful…. Friendly and helpful. The room was well furnished and clean. I would definitely stay there again. Didn’t get to use the pool because my stay was short but it looked nice."
Karlisa 1-night trip
Posted 6 hours ago
Hotel Puerto Pacifico Guayaquil Airport

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 90 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Santa Ana Hill are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Numa Pompilio Llona Street and El Carmen Hill are a couple of additional sights to visit in Guayaquil.