Hotels near Portsmouth Regional Hospital

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Dec - 28 Dec
Tomorrow
28 Dec - 29 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Portsmouth Regional Hospital hotels

Indoor pool
Holiday Inn Express Hotel & Suites Seabrook by IHG

Holiday Inn Express Hotel & Suites Seabrook by IHG

Holiday Inn Express Hotel & Suites Seabrook by IHG
2.5 star property
0.7 km from Portsmouth Regional Hospital
8.8 out of 10, Excellent, (1003)
"Second time staying here and it was convenient and the price was great! "
United States
Kimberly
The price is RM300
RM325 total
includes taxes & fees
19 Jan - 20 Jan 2026
Holiday Inn Express Hotel & Suites Seabrook by IHG
Lobby
Best Western Hampshire Inn

Best Western Hampshire Inn

Best Western Hampshire Inn
2.5 star property
0.3 km from Portsmouth Regional Hospital
8.4 out of 10, Very good, (1003)
"The room was clean, breakfast was fantastic. If it wasn’t Christmas, the location would be great because it’s near everything. "
United States
Chantal
The price is RM361
RM392 total
includes taxes & fees
30 Dec - 31 Dec
Best Western Hampshire Inn
Balcony
Hampton Falls Inn

Hampton Falls Inn

Hampton Falls Inn
2.5 star property
1.4 km from Portsmouth Regional Hospital
7.6 out of 10, Good, (1000)
"I always enjoy staying here."
United States
Gary
The price is RM292
RM325 total
includes taxes & fees
29 Dec - 30 Dec
Hampton Falls Inn
Seasonal outdoor pool
Seabrook Inn

Seabrook Inn

Seabrook Inn
2.5 star property
1.2 km from Portsmouth Regional Hospital
6.6 out of 10, (1002)
"Perfect location "
United States
Mike
The price is RM279
RM303 total
includes taxes & fees
29 Dec - 30 Dec
Seabrook Inn
Individually decorated, individually furnished, desk, iron/ironing board
Compass Rose Inn

Compass Rose Inn

Compass Rose Inn
4.0 star property
9 km from Portsmouth Regional Hospital
9.8 out of 10, Exceptional, (202)
"Amazing staff and the room was adorable! "
United States
Valerie
The price is RM927
RM1,035 total
includes taxes & fees
2 Jan - 3 Jan 2026
Compass Rose Inn
View from property
Hampton House Hotel

Hampton House Hotel

Hampton House Hotel
2.0 star property
5.8 km from Portsmouth Regional Hospital
9.4 out of 10, Exceptional, (1000)
"Place was clean staff was helpful and the view was amazing would definitely go again"
United States
john
The price is RM492
RM534 total
includes taxes & fees
29 Dec - 30 Dec
Hampton House Hotel
Premium bedding, pillow-top beds, individually furnished, desk
Lamie's Inn and The Old Salt Restaurant

Lamie's Inn and The Old Salt Restaurant

Lamie's Inn and The Old Salt Restaurant
3.0 star property
6.3 km from Portsmouth Regional Hospital
9.4 out of 10, Exceptional, (1000)
"Great property with a really great restaurant!"
United States
Steven
Lamie's Inn and The Old Salt Restaurant
View from property
Atlantic Breeze Suites

Atlantic Breeze Suites

Atlantic Breeze Suites
3.0 star property
6.3 km from Portsmouth Regional Hospital
9.4 out of 10, Exceptional, (405)
"Super clean as always. Amazing view. Easy check in and check out"
United States
Michael
The price is RM676
RM755 total
includes taxes & fees
29 Dec - 30 Dec
Atlantic Breeze Suites
2 bedrooms, premium bedding, desk, blackout curtains
Inn By The Bandstand

Inn By The Bandstand

Inn By The Bandstand
4.0 star property
11.5 km from Portsmouth Regional Hospital
9.8 out of 10, Exceptional, (66)
"Excellent and totally underrated. Highly recommend!"
United States
Joseph
The price is RM1,118
RM1,213 total
includes taxes & fees
5 Jan - 6 Jan 2026
Inn By The Bandstand
Garden
Clark Currier Inn

Clark Currier Inn

Clark Currier Inn
4.0 star property
9.3 km from Portsmouth Regional Hospital
9.6 out of 10, Exceptional, (541)
"Excellent place to stay. A charming inn with character. The owners were very friendly and helpful. Great location. Walking distance to downtown shops and restaurants."
United States
Joshua
The price is RM815
RM911 total
includes taxes & fees
29 Dec - 30 Dec
Clark Currier Inn
Desk, iron/ironing board, free WiFi, bed sheets
SpringHill Suites by Marriott Hampton Portsmouth

SpringHill Suites by Marriott Hampton Portsmouth

SpringHill Suites by Marriott Hampton Portsmouth
2.5 star property
7.4 km from Portsmouth Regional Hospital
9.4 out of 10, Exceptional, (847)
"Yes everything was excellent. Loved having a handicapped accessable room due to having my mom who's 77 year's old. It was clean and no problems heat worked great "
United States
Sharon
The price is RM413
RM448 total
includes taxes & fees
4 Jan - 5 Jan 2026
SpringHill Suites by Marriott Hampton Portsmouth
Exterior
Essex Street Inn & Suites, an Ascend Collection Hotel

Essex Street Inn & Suites, an Ascend Collection Hotel

Essex Street Inn & Suites, an Ascend Collection Hotel
3.5 star property
9.2 km from Portsmouth Regional Hospital
9.4 out of 10, Exceptional, (679)
"Very clean and nice place. Great location in town."
United States
Alfonso
The price is RM410
RM518 total
includes taxes & fees
18 Jan - 19 Jan 2026
Essex Street Inn & Suites, an Ascend Collection Hotel
Premium bedding, individually decorated, desk, blackout curtains
Garrison Inn Boutique Hotel

Garrison Inn Boutique Hotel

Garrison Inn Boutique Hotel
3.0 star property
9.1 km from Portsmouth Regional Hospital
9.4 out of 10, Exceptional, (406)
"Love it here, perfect location and beautiful hotel!"
United States
Amanda
The price is RM1,337
RM1,493 total
includes taxes & fees
29 Dec - 30 Dec
Garrison Inn Boutique Hotel
View from room
Blue - Inn on The Beach

Blue - Inn on The Beach

Blue - Inn on The Beach
3.5 star property
12.3 km from Portsmouth Regional Hospital
9.6 out of 10, Exceptional, (202)
"Clean, great view, staff and breakfast was exceptional. "
United States
Patrick
The price is RM880
RM1,080 total
includes taxes & fees
4 Jan - 5 Jan 2026
Blue - Inn on The Beach
Front of property
The Victoria Inn

The Victoria Inn

The Victoria Inn
3.5 star property
7.6 km from Portsmouth Regional Hospital
9.2 out of 10, Wonderful, (120)
"Property was beautiful, rooms were excellent and breakfast was delicious. "
United States
anna
The price is RM729
RM791 total
includes taxes & fees
18 Jan - 19 Jan 2026
The Victoria Inn
Exterior
Hampton Inn by Hilton Amesbury

Hampton Inn by Hilton Amesbury

Hampton Inn by Hilton Amesbury
2.5 star property
5.7 km from Portsmouth Regional Hospital
9.0 out of 10, Wonderful, (1000)
"Perfect location and facilities "
United States
kathleen
The price is RM395
RM441 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn by Hilton Amesbury
Exterior
Hampton Inn & Suites Exeter

Hampton Inn & Suites Exeter

Hampton Inn & Suites Exeter
2.5 star property
11.4 km from Portsmouth Regional Hospital
9.2 out of 10, Wonderful, (1002)
"Clean room, friendly staff"
United States
Barbara
The price is RM379
RM411 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hampton Inn & Suites Exeter
Individually furnished, free WiFi, bed sheets
Blue Jay Motel

Blue Jay Motel

Blue Jay Motel
2.0 star property
4.9 km from Portsmouth Regional Hospital
8.6 out of 10, Excellent, (191)
"Great place to stay while visiting Hampton Beach!"
United States
James
The price is RM580
RM629 total
includes taxes & fees
29 Dec - 30 Dec
Blue Jay Motel
In-room safe, desk, laptop workspace, blackout curtains
Fairfield Inn By Marriott Amesbury

Fairfield Inn By Marriott Amesbury

Fairfield Inn By Marriott Amesbury
2.5 star property
6.1 km from Portsmouth Regional Hospital
8.6 out of 10, Excellent, (1003)
"Very comfortable and enjoyed breakfast "
United States
Kristen
The price is RM392
RM438 total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn By Marriott Amesbury
Front of property
Exeter Inn

Exeter Inn

Exeter Inn
3.5 star property
11.5 km from Portsmouth Regional Hospital
9.0 out of 10, Wonderful, (1002)
"Service in the restaurant was great we ate both dinner and had brunch on Sunday food was good and atmosphere was nice. "
United States
Kelly
Exeter Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Portsmouth Regional Hospital Hotel Reviews

Hampton House Hotel

Hampton House Hotel

10/10 Excellent
"Place was clean staff was helpful and the view was amazing would definitely go again"
john 1-night trip
Posted 6 days ago
Hampton House Hotel

Hotels near other Portsmouth Regional Hospital attractions

Aerial view of Seabrook Beach, New Hampshire with snow

Seabrook Beach

4.3/5 (23 reviews)
If a restful holiday is part of your travel plans, Seabrook Beach might be the perfect place to visit during your trip to Seabrook. Visit the shops in this family-friendly area or simply enjoy its restaurants.
See properties
Hampton Beach panorama aerial view including historic waterfront buildings on Ocean Boulevard and Hampton Beach State Park, Town of Hampton, New Hampshire NH, USA.

Hampton Beach State Park

4.4/5 (513 reviews)
Why not spend a care-free afternoon at Hampton Beach State Park during your travels in Hampton? Stroll along the area's seaside or simply savour its top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Portsmouth Regional Hospital?
Portsmouth Regional Hospital is located in Seabrook. This family-friendly area is known for its beautiful beaches. You'll find 605 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay close to Portsmouth Regional Hospital?
Adjacent to Portsmouth Regional Hospital, Best Western Hampshire Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Holiday Inn Express Hotel & Suites Seabrook by IHG and Seabrook Inn.
How many hotels can I expect to find near Portsmouth Regional Hospital?
Expedia has 605 hotels and other accommodation options a few miles from Portsmouth Regional Hospital.
If I need to cancel the hotel reservation for my stay near Portsmouth Regional Hospital, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to review the top deals on offer near Portsmouth Regional Hospital.
What can I see and do near Portsmouth Regional Hospital?
James House, Tuck Museum and Seacoast Fire Museum feature captivating exhibits. Explore notable local landmarks like Lowell's Boat Shop, Port City Tours and Mary Baker Eddy Historic House. You might spend a leisurely day outdoors at Salisbury Beach State Reservation and Atkinson Common.