A wooden bridge over water, surrounded by palm trees and outdoor seating areas.

Plantation Key Business Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Plantation Key Business Hotels

Tonight
26 Sept - 27 Sept
Tomorrow
27 Sept - 28 Sept
Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

Our top choices for Plantation Key business-friendly hotels

A beach with hammocks under palm trees, a sandy beach, and a clear blue sky.
A hotel room with a bed, a TV, a sofa, and a balcony with a view.
A modern kitchen with a built-in stove, a large island, and a view to a balcony with outdoor seating.
A resort with a pool, multiple buildings, and a waterfront view.

1. Dove Creek Resort & Marina, Trademark Collection by Wyndham

Dove Creek Resort & Marina, Trademark Collection by Wyndham
Key Largo
United States
Omar Ahmad
RM401
RM581 total
includes taxes & fees
4 Oct - 5 Oct
Dove Creek Resort & Marina, Trademark Collection by Wyndham
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.

2. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
United States
RAIBEL
RM609
RM984 total
includes taxes & fees
29 Sept - 30 Sept
Cheeca Lodge & Spa
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A bar area with a wooden counter, bar stools, and potted plants.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.
A wooden pier leading to a beach with palm trees and a row of beach huts.

3. Islander Resort

Islander Resort
Matecumbe
United States
John
RM883
RM1,292 total
includes taxes & fees
7 Oct - 8 Oct
Islander Resort
A beach with palm trees, lounge chairs, and a clear view of the ocean.
A resort with a thatched-roof structure, palm trees, and lounge chairs on a sandy beach.
A hotel room with a kitchenette, two beds, a desk, a television, and a ceiling fan.
A clear blue pool with lounge chairs and palm trees.

4. Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay
Key Largo
United States
Ruddy
RM486
RM547 total
includes taxes & fees
6 Oct - 7 Oct
Hampton Inn Key Largo Manatee Bay
Two hands holding wine glasses with a beach and ocean view in the background.
A hand holding a card with the Bayside Inn logo, palm trees, and a beach setting in the background.
An aerial view of a resort with a swimming pool, beach area, and dock.
A bed with white and turquoise pillows, a bottle of champagne, and two glasses on a round table.

5. Bayside Inn Key Largo

Bayside Inn Key Largo
Key Largo
United States
Lwigy
RM440
RM596 total
includes taxes & fees
27 Sept - 28 Sept
Bayside Inn Key Largo
A balcony with wicker chairs and a small table overlooking a marina with boats and palm trees.
A modern kitchen with a curved island, stainless steel appliances, and a menu board.
A marina with multiple boats docked, surrounded by palm trees and buildings.
A modern room with a large window, a grey sofa, a lamp, and a view of a pool and palm trees.

6. Courtyard by Marriott Key Largo

Courtyard by Marriott Key Largo
Key Largo
United States
Jennifer
RM656
RM738 total
includes taxes & fees
30 Sept - 1 Oct
Courtyard by Marriott Key Largo
A resort with a swimming pool, lounge chairs, and palm trees.
A beach with palm trees and a clear view of the ocean.
A spacious living area with a large island, wooden furniture, and a ceiling fan.

7. Lime Tree Bay Resort

Lime Tree Bay Resort
Long Key
United States
Angela
RM471
RM713 total
includes taxes & fees
29 Sept - 30 Sept
Lime Tree Bay Resort
An aerial view of a resort with a large pool, palm trees, and a beach.
A beachside patio with lounge chairs, a table, and a view of the ocean.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.

8. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Tania
RM1,071
RM1,430 total
includes taxes & fees
25 Oct - 26 Oct
Playa Largo Resort & Spa, Autograph Collection
A wooden deck with a view of the ocean and a palm tree.
A coconut drink with a straw, a cherry, and a slice of fruit on a table by a pool with a waterfall and palm trees in the background.
A spacious interior with a high ceiling, large windows, and a central chandelier.
A hammock on a sandy beach with a view of the sea and a tree overhead.

9. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Milagros
RM1,072
RM1,431 total
includes taxes & fees
28 Sept - 29 Sept
Baker's Cay Resort Key Largo, Curio Collection by Hilton
An aerial view of a beach resort with a dock, thatched-roof structures, and a clear blue sky.
A beach with thatched umbrellas, lounge chairs, and wooden benches.
An aerial view of a resort with a pool area illuminated by blue lights, surrounded by palm trees and thatched-roof structures.
A hotel room with two beds, a wooden floor, a window with a view of the city, and a small desk with a chair.

10. Gilbert's Resort

Gilbert's Resort
Key Largo
United Kingdom
Anthony
RM852
RM959 total
includes taxes & fees
28 Sept - 29 Sept
Gilbert's Resort
View all properties

Top Plantation Key Hotel Reviews

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

8/10 Good
"Was clean a little sparse & in need of updating. The staff was extremely helpful. The private beach was very nice."
Angela 1-night trip
Posted 5 hours ago
The Pelican Key Largo Cottages
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"This is my second time staying at this property. I loved it both times. The rooms are clean and spacious"
Alexis 4-night trip
Posted 5 hours ago
Sunset Cove Beach Resort
Islander Resort

Islander Resort

8/10 Good
"I liked the fact that our rear outside seating area was quite private because of the trees and bushes growing around the property. Very peaceful and also just a couple of minutes walk from the sea."
norman 4-night trip
Posted 8 hours ago
Islander Resort
Waterside Suites & Marina

Waterside Suites & Marina

8/10 Good
"Comfortable bed, clean . It’s off the busy road and close to restaurants"
Maureen 3-night trip
Posted 10 hours ago
Waterside Suites & Marina
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"There are some nice food and beverage options. Water sports 8n the property."
John 3-night trip
Posted 13 hours ago
Reefhouse Resort & Marina
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Great location !!"
Jenny 2-night trip
Posted 2 days ago
Bayside Inn Key Largo
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

8/10 Good
"Decent hotel to stay at. Breakfast was pricey, we searched elsewhere to eat. We couldn’t connect to the WiFi in the room the whole week. Their tech tried to help, but no luck. Close to restaurants and sites that we wanted to go visit."
Ann 5-night trip
Posted 7 days ago
Holiday Inn Key Largo by IHG

Explore a world of travel with Expedia