𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Perryville from RM299 (2026) - Fully Refundable Options

A train crossing a stone bridge over a river, surrounded by lush greenery.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Perryville

Pet friendly

Pool

Apartment

Family friendly

Waterpark

Condo

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Perryville hotels

Breakfast included

Hotel

Pool

Pet friendly

Reserve now, pay later

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A Holiday Inn Express & Suites building with a covered entrance and multiple windows.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.

A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

1. Holiday Inn Express & Suites Perryville by IHG

Perryville

Kristen

RM392

RM449 total

includes taxes & fees

30 Aug - 31 Aug

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

2. Super 8 by Wyndham Perryville

Perryville

Elizabeth

RM261

RM299 total

includes taxes & fees

15 Sept - 16 Sept

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A playground with a wooden playhouse, a slide, and two animal-shaped swings.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

3. Perryville RV Resort

Perryville

Von

RM268

RM307 total

includes taxes & fees

27 Aug - 28 Aug

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a sign that reads "The Atrium Boutique Hotel".

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

4. The Atrium - A Boutique Hotel

Perryville

Brian

RM306

RM645 total

includes taxes & fees

27 Aug - 28 Aug

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A kitchen with wooden cabinets, a dining area with a table and chairs, and various kitchen appliances.

A hotel hallway with a patterned carpet, blue walls, and a sign indicating an office.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

5. Days Inn by Wyndham Perryville

Perryville

Wanda

RM273

RM312 total

includes taxes & fees

27 Aug - 28 Aug

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

A hotel room with a large bathtub, a bed with two pillows, a nightstand, and a wall-mounted lamp.

A hotel room with a desk, a television, a coffee maker, a chair, and a window with curtains.

6. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

RM273

RM312 total

includes taxes & fees

1 Sept - 2 Sept

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A hallway with exposed brick walls, wooden flooring, and a white door.

7. Urban Lofts

Perryville

Grace

RM815

RM1,257 total

includes taxes & fees

27 Aug - 28 Aug

A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

A kitchen with a large black sink, a window with a view of trees, and a microwave on the counter.

A room with a white door, a radiator, a blue carpet, and a mural on the wall.

A two-story building with a balcony, a front door with a wreath, and a sign indicating a restaurant.

8. The Mediterranean House 1858

Perryville

RM2,034

RM3,301 total

includes taxes & fees

9 Sept - 10 Sept

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A hotel room with two beds, a brick wall, and a wooden headboard.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

9. Drury Inn & Suites Jackson MO

Jackson

Jamie

RM352

RM372 total

includes taxes & fees

17 Sept - 18 Sept

A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

A room with a fireplace, a mounted deer head, a bookshelf, and two armchairs.

A breakfast area with a counter, seating, and kitchen appliances.

A modern bathroom with a large bathtub, a wooden floor, and a dark wall with a colorful abstract painting.

10. Baymont by Wyndham Chester IL

Chester

Keng

RM313

RM347 total

includes taxes & fees

30 Aug - 31 Aug

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

11. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Shawn

RM357

RM387 total

includes taxes & fees

27 Aug - 28 Aug

A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.

A hot tub area with a view of the parking lot through a glass door.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

A large brick building with a central entrance flanked by columns, likely a hotel or office building.

12. Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

Keisha

RM408

RM453 total

includes taxes & fees

4 Sept - 5 Sept

A room with a wooden table, two patterned chairs, a framed artwork on the wall, and a window with brown curtains.

A compact kitchen with black cabinets, a black refrigerator, a microwave, and a sink.

A parking lot with a sign for Triangle Inn.

13. Triangle Inn Motel

Ste Genevieve

Pamela

RM278

RM327 total

includes taxes & fees

1 Sept - 2 Sept

A row of single-story houses with attached garages, a paved driveway, and a clear sky.

A hotel dining area with tables and chairs, a kitchen area, and a flat-screen TV mounted on the wall.

A hotel room with two beds, a desk, a chair, and a window with curtains.

A modern living room with a flat-screen TV, a desk with a computer, two armchairs, a coffee table, and large windows with a view.

14. Microtel Inn & Suites by Wyndham Sainte Genevieve

Ste Genevieve

Samantha

RM367

RM432 total

includes taxes & fees

27 Aug - 28 Aug

A modern retail area with a display of local items and snacks.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

15. Tru By Hilton Cape Girardeau

Cape Girardeau

Gwendolyn

RM361

RM411 total

includes taxes & fees

6 Sept - 7 Sept

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

16. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

RM361

RM391 total

includes taxes & fees

1 Sept - 2 Sept

A motel with a covered entrance, a flag, and a phone number.

A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.

A spacious kitchen with a dining area, featuring a ceiling fan, a TV mounted on the wall, and a large rug in the center.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

17. Madison Inn Lodge

Fredericktown

Christine

RM354

RM386 total

includes taxes & fees

8 Sept - 9 Sept

A large, two-story house with a wrap-around porch and a central tower.

A four-poster canopy bed with a wooden headboard, a chandelier, and a radiator on the floor.

A room with a red velvet sofa, a chandelier, a mirror, and a vanity with a sink.

A covered patio with a picnic table, surrounded by a brick pathway and greenery.

18. The Conner House B&B

Prairie du Rocher

James

RM632

RM701 total

includes taxes & fees

6 Sept - 7 Sept

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

19. Town House Inn

Jackson

Taylor

RM288

RM312 total

includes taxes & fees

27 Aug - 28 Aug

A modern bedroom with a large bed, a desk with a computer, a chair, and a window with a view of a lake.

A motel with a blue exterior, a central garage entrance, and a parking lot with several cars.

A bathroom with a beige sink, a mirror, a towel rack, and a trash bin.

20. Briarwood Inn of Sparta

Sparta

Steve

RM360

RM399 total

includes taxes & fees

5 Sept - 6 Sept

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

8.8/10 (19 reviews)

This serene Catholic shrine honours the Miraculous Medal with exquisite stained glass and intricate murals. Visitors find spiritual renewal along the peaceful Rosary Walk and Marian Grotto gardens.

See properties

Saint Marys Lake

Saint Marys Lake offers a tranquil escape in Missouri's countryside with serene waters reflecting the changing seasons. Bring a picnic and binoculars to spot local wildlife while enjoying this peaceful local reservoir.

See properties

County Lake State Wildlife Management Area

This peaceful 103-acre reservoir offers exceptional fishing for largemouth bass, bluegill, and hybrid striped bass. Cast your line near brush piles and vegetation beds for the best chance at a memorable catch.

See properties

Perryville Country Club

6.6/10 (7 reviews)

This classic 9-hole course features Zoysia fairways and Bent grass greens dating back to 1932. Enjoy a challenging round followed by refreshments at the clubhouse overlooking the scenic Missouri landscape.

See properties

Missouri's National Veterans Memorial

9.2/10 (14 reviews)

This full-scale replica of the Vietnam Veterans Memorial offers a profound space for reflection away from Washington D.C. Walk the black granite wall inscribed with 58,000 names in Missouri's countryside.

See properties

Feltz Street Park

This community park features a gentle 0.41-mile loop trail and pickleball court. Bring your own equipment and enjoy this peaceful local spot during spring or fall for the best outdoor experience.

See properties

Perryville City Hall

Perryville City Hall serves as the administrative heart of this Missouri town, housing essential government offices. Visit during weekday business hours to access city services or attend public meetings.

See properties

James M. Eddleman Millitary Museum

This veteran-founded museum honours military service through authentic Vietnam War artefacts and personal stories. Explore Jim Eddleman's collection and experience history through the eyes of those who lived it.

See properties

Perryville and related destinations

Historic battlefields and the charming city centre district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Centre and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend.

See all hotels in Perryville

Top Perryville Hotel Reviews

Madison Inn Lodge

10/10 Excellent

"Great experience"

Tru By Hilton Cape Girardeau

8/10 Good

"Staff was friendly and welcoming."

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent

"Great hotel very clean great food"

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"Clean room and property, great breakfast and workout facilities. Definitely stay here again"

Microtel Inn & Suites by Wyndham Sainte Genevieve

8/10 Good

"The Breakfast items were a bit stale. Staff was not super helpful."

Perryville RV Resort

10/10 Excellent

"Great time"

Urban Lofts

10/10 Excellent

"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."

More cheap stays in Perryville

Super 8 by Wyndham Perryville

1119 Vincent Dr Perryville MO

RM261

RM299 total

15 Sept - 16 Sept

includes taxes & fees

Baymont by Wyndham Chester IL

2150 State Street Chester IL

RM313

RM347 total

30 Aug - 31 Aug

includes taxes & fees

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

RM361

RM411 total

6 Sept - 7 Sept

includes taxes & fees

9.6/10 Exceptional! (173 reviews)

Microtel Inn & Suites by Wyndham Sainte Genevieve

21958 Hwy 32 Ste Genevieve MO

RM367

RM432 total

27 Aug - 28 Aug

includes taxes & fees

8.8/10 Excellent! (665 reviews)

Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St Perryville MO

RM392

RM449 total

30 Aug - 31 Aug

includes taxes & fees

9.2/10 Wonderful! (617 reviews)

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

120 MUDDY MONSTER ROAD Murphysboro IL

RM477

RM529 total

31 Aug - 1 Sept

includes taxes & fees

9.4/10 Exceptional! (596 reviews)

Frequently asked questions

What's the best place for a stay in Perryville?

Holiday Inn Express & Suites Perryville by IHG is one of the top choices for your stay based on our traveller data. This hotel offers free breakfast and an indoor pool. Other good choices for your stay include Super 8 by Wyndham Perryville and Days Inn by Wyndham Perryville. See all available top hotels, or vacation rentals in Perryville.

If I need to cancel my hotel reservation in Perryville, will I receive a refund?

Yes, the majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Perryville.

What is the favourite LGBTQ-friendly accommodation in Perryville?

Holiday Inn Express & Suites Perryville by IHG is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. See all available hotels listed as LGBTQ-friendly in Perryville.

What's the best dog-friendly place to stay in Perryville?

Days Inn by Wyndham Perryville is a top hotel for people travelling with their pets, and offers a seasonal outdoor pool and laundry facilities for its human guests. Other good choices for you and your pet's trip include Super 8 by Wyndham Perryville and Perryville RV Resort. See more pet-friendly hotel accommodations in Perryville.

What are some hotels with pools in Perryville?

Quality Inn Perryville I-55 is a top hotel with a seasonal outdoor pool, free breakfast and free WiFi. View all hotels with pools in Perryville.

What is staying in Perryville like?

Visitors can enjoy all that Perryville has to offer, including the wineries, golf courses and coffee shops. Tourists can also enjoy the city's festivals, university setting and parks. In Perryville, there are 26 hotels and other accommodation options to choose from. Find out more about Perryville.

What is there to see in Perryville?

Landmarks like National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial might be worth a visit. Natural beauty is on display at Mark Twain National Forest, Mississippi River and Feltz Street Park. A couple of additional sights to add to your itinerary are Perryville City Hall and Perryville Country Club. Take a look at what more there is to see and do in Expedia's Perryville guide.

What's the seasonal weather in Perryville?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Perryville is 1219 mm.

Perryville hotels from RM299

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Perryville

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Perryville hotels

1. Holiday Inn Express & Suites Perryville by IHG

2. Super 8 by Wyndham Perryville

3. Perryville RV Resort

4. The Atrium - A Boutique Hotel

5. Days Inn by Wyndham Perryville

6. Quality Inn Perryville I-55

7. Urban Lofts

8. The Mediterranean House 1858

9. Drury Inn & Suites Jackson MO

10. Baymont by Wyndham Chester IL

11. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

12. Holiday Inn Express Hotel & Suites Sparta by IHG

13. Triangle Inn Motel

14. Microtel Inn & Suites by Wyndham Sainte Genevieve

15. Tru By Hilton Cape Girardeau

16. Comfort Suites Jackson-Cape Girardeau

17. Madison Inn Lodge

18. The Conner House B&B

19. Town House Inn

20. Briarwood Inn of Sparta

Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

Saint Marys Lake

County Lake State Wildlife Management Area

Perryville Country Club

Missouri's National Veterans Memorial

Feltz Street Park

Perryville City Hall

James M. Eddleman Millitary Museum

Perryville and related destinations

Top Perryville Hotel Reviews

Madison Inn Lodge

Tru By Hilton Cape Girardeau

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Perryville by IHG

Microtel Inn & Suites by Wyndham Sainte Genevieve

Perryville RV Resort

Urban Lofts

More cheap stays in Perryville

Super 8 by Wyndham Perryville

Baymont by Wyndham Chester IL

Tru By Hilton Cape Girardeau

Microtel Inn & Suites by Wyndham Sainte Genevieve

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app