Photo by Angela Pennefather

Guest Houses in Penama

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
8 Aug - 10 Aug
In two weeks
15 Aug - 17 Aug
In one month
29 Aug - 31 Aug
In two months
26 Sept - 28 Sept

Featured Guest Houses in Penama

Santo Seaside Villas
Explore the vibrant coral reef from the comfort of a nearby boat.

Santo Seaside Villas

3.0 star property
10.0 out of 10, Exceptional, (1)
Santo Seaside Villas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Penama Hotel Reviews

The Espiritu

The Espiritu

10/10 Excellent
"Such a great stay! We were really busy on different outings throughout our time but our room was so pleasant to go back to and get the rest we needed. Very comfortable and great staff! We felt very taken care of the whole time. "
Zechariah 5-night trip
Posted 3 weeks ago
The Espiritu