A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City Spa Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Panama City Hotels with Spa

Tonight
19 Oct - 20 Oct
Tomorrow
20 Oct - 21 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Panama City hotels with a spa

A modern spa area with a hot tub, seating, and a city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop pool area with purple lounge chairs and a city skyline in the background.
A rooftop lounge with modern seating and a panoramic city view.

1. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
  • Immerse in therapeutic bliss with 2 spa rooms, steam, and sauna at this full-service wellness hotel.
RM652
RM717 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A poolside area with lounge chairs and a view of the ocean.
A balcony with a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.

2. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Immerse in waterfront tranquility with bay views, rejuvenating in-room massages, and four outdoor pools for a complete spa getaway.
RM1,140
RM1,254 total
includes taxes & fees
6 Nov - 7 Nov
JW Marriott Panama
A covered outdoor seating area with a view of a city skyline and water.
A hotel room with two beds, a desk, and a large window offering a city view.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.
A restaurant with large windows offering a view of a city skyline and palm trees.

3. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
San Francisco
  • Unwind with hot stone massages and facials at this hotel spa with pool views and plush treatment rooms.
RM535
RM589 total
includes taxes & fees
1 Nov - 2 Nov
Plaza Paitilla Inn Hotel
A room with two beds, a desk, a chair, and a window with a view of greenery.
A reception desk with a clock and a no-smoking sign.
A table and two chairs in a shaded outdoor area with a view of a water body and greenery.
A conference room with round tables, white chairs, and a projector screen on the wall.

4. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
  • Rejuvenate at this tranquil resort with pampering spa services, a stunning pool with swim-up bar, and lush gardens perfect for unwinding.
RM442
RM486 total
includes taxes & fees
26 Oct - 27 Oct
Riande Aeropuerto Hotel & Casino
A hotel room with a checkered floor, a window with white curtains, and a lounge area with chairs and tables.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A balcony with a city view, a table with a drink, chairs, and a potted orchid.
A balcony with a table, chairs, and a view of a city skyline across a body of water.

5. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
RM1,433
RM1,576 total
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
A modern building facade with large glass windows and a visible sign for 'AQUA SPA'.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.
An outdoor dining area with clear glass tables and chairs, surrounded by palm trees and modern buildings.

6. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
  • Revive in Panama's premier hotel spa with Turkish hammam, hydrotherapy, and multiple treatment rooms for total rejuvenation.
RM359
RM395 total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A reception desk with a logo, a patterned wall, and a potted plant.
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern interior with a spiral staircase, a large window, and a seating area.
A modern bathroom with a glass-enclosed shower, a freestanding bathtub, and a view of a cityscape through large windows.

7. Hilton Panama

Hilton Panama
Bella Vista
  • Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
RM1,072
RM1,179 total
includes taxes & fees
8 Nov - 9 Nov
Hilton Panama
A bedroom with a large wooden wardrobe, a bed with a beige blanket, a pillow with a 'H' logo, and a wall mural of a tree.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.
A multi-story building with balconies, arched windows, and decorative railings.

8. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
  • Discover revitalising massages and soothing facials at this historic hotel with a rooftop pool and steam room in Panama's vibrant centre.
RM829
RM912 total
includes taxes & fees
19 Nov - 20 Nov
Central Hotel Panama Casco Viejo
A rooftop pool with sun loungers and a city skyline in the background.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.

9. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
  • Immerse in a full-service spa retreat with 4 treatment rooms, sauna, and steam room at this modern bed & breakfast.
RM386
RM649 total
includes taxes & fees
20 Oct - 21 Oct
Waymore Hotel Spa & Casino
A bathroom with a large mirror, a sink, and a towel with a flower on a tray.
A restaurant with multiple dining tables, chairs, and a central water feature.
A bar area with multiple seating options, a bar counter, and a fireplace.
A historic building with ornate stonework and a balcony with plants.

10. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Soak in this colonial retreat's full-service spa sanctuary with rooftop pool and historic charm, creating a rejuvenating wellness escape.
RM1,141
RM1,256 total
includes taxes & fees
21 Oct - 22 Oct
Hotel La Compañía Casco Antiguo
View all properties

Choose what matters most at spa hotels in Panama City

Pool
Hot tub
Breakfast included
Gym
5 stars

Spa hotels with pools in Panama City

A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.
A modern spa area with a hot tub, seating, and a city view.

Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
RM652
RM717 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.

Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
RM359
RM395 total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A rooftop pool with sun loungers and a city skyline in the background.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
RM386
RM649 total
includes taxes & fees
20 Oct - 21 Oct
Waymore Hotel Spa & Casino
A covered outdoor seating area with a view of a city skyline and water.
A hotel room with two beds, a desk, and a large window offering a city view.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.
A restaurant with large windows offering a view of a city skyline and palm trees.

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
San Francisco
RM535
RM589 total
includes taxes & fees
1 Nov - 2 Nov
Plaza Paitilla Inn Hotel
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A spacious lobby with a staircase, seating area, and a bar.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
RM531
RM584 total
includes taxes & fees
1 Nov - 2 Nov
Las Americas Golden Tower Panama
A trampoline with a safety net in a grassy area with trees in the background.
A reception area with a receptionist, a statue, and a digital display.
A room with two beds, a desk, a chair, and a window with a view of greenery.
A conference room with a long table, chairs, and a carpeted floor.

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
RM442
RM486 total
includes taxes & fees
26 Oct - 27 Oct
Riande Aeropuerto Hotel & Casino
A poolside area with lounge chairs and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A terrace with seating and a view of the ocean.

JW Marriott Panama

JW Marriott Panama
San Francisco
RM1,140
RM1,254 total
includes taxes & fees
6 Nov - 7 Nov
JW Marriott Panama
A restaurant with multiple dining tables, chairs, and a central water feature.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.
A historic building with ornate stonework and a balcony with plants.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
RM1,141
RM1,256 total
includes taxes & fees
21 Oct - 22 Oct
Hotel La Compañía Casco Antiguo
A multi-story building with balconies, arched windows, and decorative railings.
A building with a balcony and a street view.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
RM829
RM912 total
includes taxes & fees
19 Nov - 20 Nov
Central Hotel Panama Casco Viejo
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.

W Panama

W Panama
Bella Vista
RM944
RM1,038 total
includes taxes & fees
1 Nov - 2 Nov
W Panama
View all properties

Spa hotels with hot tubs in Panama City

A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.

Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
RM359
RM395 total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.
A modern spa area with a hot tub, seating, and a city view.

Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
RM652
RM717 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
A rooftop pool with sun loungers and a city skyline in the background.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
RM386
RM649 total
includes taxes & fees
20 Oct - 21 Oct
Waymore Hotel Spa & Casino
A multi-story building with balconies, arched windows, and decorative railings.
A building with a balcony and a street view.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
RM829
RM912 total
includes taxes & fees
19 Nov - 20 Nov
Central Hotel Panama Casco Viejo
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.

W Panama

W Panama
Bella Vista
RM944
RM1,038 total
includes taxes & fees
1 Nov - 2 Nov
W Panama
A buffet with various food items and a decorative plant.
A hotel with a swimming pool, outdoor seating, and a modern architectural design.
A spa area with a hot tub, candles, and a curved bench.
A gym with treadmills, weight machines, and a red carpet.

Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
RM753
RM828 total
includes taxes & fees
1 Nov - 2 Nov
Sheraton Grand Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.

Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
RM1,072
RM1,179 total
includes taxes & fees
7 Nov - 8 Nov
Waldorf Astoria Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern bar area with seating and a view of the city.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.

Hilton Panama

Hilton Panama
Bella Vista
RM1,072
RM1,179 total
includes taxes & fees
8 Nov - 9 Nov
Hilton Panama
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.
A well-maintained garden with a pathway leading to a gazebo, surrounded by palm trees and a view of the sea.

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
RM1,142
RM1,142 total
includes taxes & fees
20 Oct - 21 Oct
Dreams Playa Bonita Panama - All Inclusive
View all properties

Spa hotels with free breakfast in Panama City

A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop lounge with modern seating and a panoramic city view.
A modern spa area with a hot tub, seating, and a city view.

Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
RM652
RM717 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.

Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
RM359
RM395 total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A rooftop pool with sun loungers and a city skyline in the background.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
RM386
RM649 total
includes taxes & fees
20 Oct - 21 Oct
Waymore Hotel Spa & Casino
A trampoline with a safety net in a grassy area with trees in the background.
A reception area with a receptionist, a statue, and a digital display.
A room with two beds, a desk, a chair, and a window with a view of greenery.
A conference room with a long table, chairs, and a carpeted floor.

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
RM442
RM486 total
includes taxes & fees
26 Oct - 27 Oct
Riande Aeropuerto Hotel & Casino
A covered outdoor seating area with a view of a city skyline and water.
A hotel room with two beds, a desk, and a large window offering a city view.
A cityscape with high-rise buildings, a waterfront, and a modern sculpture.
A restaurant with large windows offering a view of a city skyline and palm trees.

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
San Francisco
RM535
RM589 total
includes taxes & fees
1 Nov - 2 Nov
Plaza Paitilla Inn Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A terrace with seating and a view of the ocean.

JW Marriott Panama

JW Marriott Panama
San Francisco
RM1,140
RM1,254 total
includes taxes & fees
6 Nov - 7 Nov
JW Marriott Panama
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A spacious lobby with a staircase, seating area, and a bar.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
RM531
RM584 total
includes taxes & fees
1 Nov - 2 Nov
Las Americas Golden Tower Panama
A restaurant with multiple dining tables, chairs, and a central water feature.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.
A historic building with ornate stonework and a balcony with plants.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
RM1,141
RM1,256 total
includes taxes & fees
21 Oct - 22 Oct
Hotel La Compañía Casco Antiguo
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.

W Panama

W Panama
Bella Vista
RM944
RM1,038 total
includes taxes & fees
1 Nov - 2 Nov
W Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
RM1,433
RM1,576 total
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Panama City Hotel Reviews

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Excelente servicio y ubicación. Buen desayuno y restaurantes."
Jorge 3-night trip
Posted 7 hours ago
Central Hotel Panama Casco Viejo
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

8/10 Good
"Great breakfast and central location. Staff was very welcoming."
Carolina 2-night trip
Posted 15 hours ago
Las Americas Golden Tower Panama

Frequently asked questions

Looking to holiday at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Make sure you enjoy the cafes during your stay. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping centre and a fitness centre. Enjoy a facial, body scrub or detox wrap at the on-site spa. Other popular spa hotels in Panama City include Waymore Hotel Spa & Casino and Decapolis Hotel Panama City.
How many spa hotels are there in Panama City?
Expedia has 21 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Avenida Balboa.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas and offer services including facials and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.