Hotels near Palmdale Regional Medical Center

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Our top choices for Palmdale Regional Medical Center hotels

Outdoor pool
DoubleTree by Hilton Palmdale, CA

DoubleTree by Hilton Palmdale, CA

DoubleTree by Hilton Palmdale, CA
4.0 star property
1.1 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (775)
"The hotel was very nice. So clean and the staff was welcoming. "
United States
Crystal
The price is RM336
RM378 total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton Palmdale, CA
Lobby
Element Palmdale

Element Palmdale

Element Palmdale
3.0 star property
1.5 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (633)
"Stay was amazing! Our room was amazing and the staff was so friendly!"
United States
Caitlin
The price is RM386
RM433 total
includes taxes & fees
2 Jan - 3 Jan 2026
Element Palmdale
View from property
Fairfield Inn & Suites by Marriott Palmdale West

Fairfield Inn & Suites by Marriott Palmdale West

Fairfield Inn & Suites by Marriott Palmdale West
2.5 star property
3 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (495)
"The hotel was very nice and clean I appreciate it the friendly staff. "
United States
Alejandro
The price is RM421
RM473 total
includes taxes & fees
29 Dec - 30 Dec
Fairfield Inn & Suites by Marriott Palmdale West
Sports facility
Home2 Suites by Hilton Palmdale, CA

Home2 Suites by Hilton Palmdale, CA

Home2 Suites by Hilton Palmdale, CA
3.0 star property
0.8 km from Palmdale Regional Medical Center
9.0 out of 10, Wonderful, (391)
"The breakfast was great!"
United States
Wendy
The price is RM324
RM364 total
includes taxes & fees
23 Jan - 24 Jan 2026
Home2 Suites by Hilton Palmdale, CA
Reception
Embassy Suites Palmdale

Embassy Suites Palmdale

Embassy Suites Palmdale
3.5 star property
1.6 km from Palmdale Regional Medical Center
9.0 out of 10, Wonderful, (1117)
"Great location"
United States
Juan
The price is RM467
RM523 total
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites Palmdale
Property amenity
Residence Inn Palmdale Lancaster

Residence Inn Palmdale Lancaster

Residence Inn Palmdale Lancaster
3.0 star property
2.3 km from Palmdale Regional Medical Center
9.0 out of 10, Wonderful, (388)
"Everything was good. Staff was very nice. "
United States
Niquisha
The price is RM488
RM547 total
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn Palmdale Lancaster
Interior
Holiday Inn Palmdale-Lancaster by IHG

Holiday Inn Palmdale-Lancaster by IHG

Holiday Inn Palmdale-Lancaster by IHG
3.0 star property
0.8 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1008)
"Nice place to stay at !!"
United States
GAUDENCIO
The price is RM377
RM423 total
includes taxes & fees
30 Dec - 31 Dec
Holiday Inn Palmdale-Lancaster by IHG
Property amenity
Courtyard Palmdale

Courtyard Palmdale

Courtyard Palmdale
3.0 star property
2.3 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (936)
"The hotel was very clean and the staff was courteous. "
United States
Kenley
The price is RM406
RM455 total
includes taxes & fees
29 Dec - 30 Dec
Courtyard Palmdale
Restaurant
Hilton Garden Inn Palmdale

Hilton Garden Inn Palmdale

Hilton Garden Inn Palmdale
3.0 star property
2.3 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1000)
"Room was clean, staff was great!!"
United States
Cecilia
The price is RM418
RM468 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Palmdale
Free continental breakfast
Best Western Plus John Jay Inn & Suites

Best Western Plus John Jay Inn & Suites

Best Western Plus John Jay Inn & Suites
2.5 star property
0.5 km from Palmdale Regional Medical Center
8.6 out of 10, Excellent, (1001)
"Always a great place to stay. "
United States
Julio
The price is RM361
RM404 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus John Jay Inn & Suites
Exterior
Staybridge Suites Palmdale by IHG

Staybridge Suites Palmdale by IHG

Staybridge Suites Palmdale by IHG
3.0 star property
0.8 km from Palmdale Regional Medical Center
8.4 out of 10, Very good, (587)
"The staff is very friendly the room was cozy and the breakfast was delicious "
United States
Julio
The price is RM421
RM473 total
includes taxes & fees
4 Jan - 5 Jan 2026
Staybridge Suites Palmdale by IHG
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Hampton Inn & Suites Palmdale

Hampton Inn & Suites Palmdale

Hampton Inn & Suites Palmdale
2.5 star property
2 km from Palmdale Regional Medical Center
8.4 out of 10, Very good, (1002)
"Clean room and courteous staff. Complimentary breakfast is always delicious. "
United States
Tamera
The price is RM309
RM354 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Palmdale
Laptop workspace, blackout curtains, bed sheets
Woodspring Suites Palmdale - Lancaster

Woodspring Suites Palmdale - Lancaster

Woodspring Suites Palmdale - Lancaster
2.5 star property
3 km from Palmdale Regional Medical Center
8.2 out of 10, Very good, (180)
"This is one of the best places to stay away from home."
United States
Terenia
The price is RM300
RM336 total
includes taxes & fees
4 Jan - 5 Jan 2026
Woodspring Suites Palmdale - Lancaster
Outdoor pool
Palms Inn & Suites

Palms Inn & Suites

Palms Inn & Suites
2.5 star property
0.8 km from Palmdale Regional Medical Center
6.8 out of 10, (1135)
"I really enjoyed my stay."
United States
Anna
Palms Inn & Suites
Lobby
Red Roof Inn Palmdale - Lancaster

Red Roof Inn Palmdale - Lancaster

Red Roof Inn Palmdale - Lancaster
2.0 star property
1.4 km from Palmdale Regional Medical Center
5.0 out of 10, (1004)
"Very nice at check in"
United States
Christina
The price is RM267
RM299 total
includes taxes & fees
29 Dec - 30 Dec
Red Roof Inn Palmdale - Lancaster
Desk, iron/ironing board, free WiFi, bed sheets
OYO Hotel Palmdale - Antelope Valley

OYO Hotel Palmdale - Antelope Valley

OYO Hotel Palmdale - Antelope Valley
2.0 star property
1.8 km from Palmdale Regional Medical Center
5.0 out of 10, (310)
"It was a good stay for a 24-hour period"
United States
Paul
The price is RM257
RM317 total
includes taxes & fees
4 Jan - 5 Jan 2026
OYO Hotel Palmdale - Antelope Valley
Property amenity
Fairfield Inn & Suites by Marriott Lancaster Palmdale

Fairfield Inn & Suites by Marriott Lancaster Palmdale

Fairfield Inn & Suites by Marriott Lancaster Palmdale
2.5 star property
11.1 km from Palmdale Regional Medical Center
9.4 out of 10, Exceptional, (674)
"Have stayed here for the 2nd time and it has been great! "
United States
Maria
The price is RM433
RM480 total
includes taxes & fees
31 Dec - 1 Jan 2026
Fairfield Inn & Suites by Marriott Lancaster Palmdale
Property amenity
Residence Inn by Marriott Lancaster Palmdale

Residence Inn by Marriott Lancaster Palmdale

Residence Inn by Marriott Lancaster Palmdale
3.0 star property
12.8 km from Palmdale Regional Medical Center
9.4 out of 10, Exceptional, (281)
"Clean room, great staff! "
United States
Janet
The price is RM616
RM683 total
includes taxes & fees
4 Jan - 5 Jan 2026
Residence Inn by Marriott Lancaster Palmdale
Terrace/patio
TownePlace Suites by Marriott Lancaster, CA

TownePlace Suites by Marriott Lancaster, CA

TownePlace Suites by Marriott Lancaster, CA
3.0 star property
11.3 km from Palmdale Regional Medical Center
9.2 out of 10, Wonderful, (355)
"Wonderful hotel."
United States
david
The price is RM507
RM561 total
includes taxes & fees
2 Jan - 3 Jan 2026
TownePlace Suites by Marriott Lancaster, CA
Balcony view
Oxnard Inn Lancaster

Oxnard Inn Lancaster

Oxnard Inn Lancaster
3.0 star property
10.4 km from Palmdale Regional Medical Center
8.8 out of 10, Excellent, (1006)
"Great customer service and delicious breakfast. "
United States
Noe
The price is RM383
RM423 total
includes taxes & fees
4 Jan - 5 Jan 2026
Oxnard Inn Lancaster
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Palmdale Regional Medical Center Hotel Reviews

Hotel Burbank

Hotel Burbank

10/10 Excellent
"Very clean and nice updated room. "
Priscilla 1-night trip
Posted 2 days ago
Hotel Burbank

Hotels near other Palmdale Regional Medical Center attractions

I <3 this place! I hope I can find w place like this back in WA!
Photo by Christine Buggs
Open Photo by Christine Buggs

Antelope Valley Mall

4.1/5 (133 reviews)
You can find the perfect gifts to bring home at Antelope Valley Mall during your stay in Palmdale. Visit the shops and top-notch restaurants in this family-friendly area.
See properties
Panoramic image looking east of Palmdale in Los Angeles county showing the California aqueduct in the foreground.

Lake Palmdale

4.1/5 (36 reviews)
Commune with nature and explore the great outdoors at Lake Palmdale during your travels in Palmdale. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Frequently asked questions

What's the area like around Palmdale Regional Medical Center?
Palmdale Regional Medical Center is located in a welcoming area of Palmdale known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 29 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Palmdale Regional Medical Center?
DoubleTree by Hilton Palmdale, CA is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.7 mi (1.1 km) from Palmdale Regional Medical Center. Another good choice is Embassy Suites Palmdale, located 1 mi (1.6 km) away.
How many hotels should I expect to find close to Palmdale Regional Medical Center?
Expedia has 29 hotels and other accommodation options within a mile from Palmdale Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Palmdale Regional Medical Center, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals near Palmdale Regional Medical Center.
What can I see and do near Palmdale Regional Medical Center?
You can enjoy live performances at Palmdale Playhouse and Palmdale Amphitheater. If you have some time to wander around the area, you might stop by Antelope Valley Country Club, Rancho Vista Golf Club or Cinemark Antelope Valley Mall. If you want to see more of the surrounding area, you can plan a visit to Antelope Valley Mall and Palmdale City Hall.