10 Best Business Hotels in Ortygia for 2026

A waterfront promenade at sunset with a row of buildings and a railing along the path.

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Our top choices for Ortygia business-friendly hotels

A historic building with a central entrance, multiple balconies, and a large potted plant in front.

1. Algila' Ortigia Charme Hotel

Ortigia

Steven

RM909 total

includes taxes & fees

4 Nov - 5 Nov

A balcony with a view of the sea, a cactus, and potted plants.

2. Grand Hotel Ortigia Siracusa

Ortigia

SEAN

RM1,233 total

includes taxes & fees

16 Nov - 17 Nov

A wooden table with a plate of fruit and two glasses of orange juice.

3. Dimore delle Zagare Ortigia

Ortigia

Graham

RM551 total

includes taxes & fees

17 Nov - 18 Nov

A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.

4. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Ortigia

nadia

RM3,144 total

includes taxes & fees

3 Nov - 4 Nov

A table with drinks and a view of the sea.

5. Hotel Posta

Ortigia

Steven

RM402 total

includes taxes & fees

15 Nov - 16 Nov

A stone wall with a small pool, two white pitchers, and a vase.

6. CinqueSuites Ortigia

Ortigia

Dongni

RM368 total

includes taxes & fees

3 Nov - 4 Nov

A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.

7. Ortea Palace Hotel, Sicily, Autograph Collection

Ortigia

ALFONSO

RM1,352 total

includes taxes & fees

11 Nov - 12 Nov

A balcony with a view of the sea, featuring a metal railing and potted plants.

8. Domus Mariae Albergo

Ortigia

Hadi

RM480 total

includes taxes & fees

9 Nov - 10 Nov

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Top Ortygia Hotel Reviews

Algila' Ortigia Charme Hotel

10/10 Excellent

"Awesome staff Very clean, great breakfast"

Grand Hotel Ortigia Siracusa

10/10 Excellent

"I enjoyed four unforgettable days exploring beautiful Ortigia -staying at the Grand Hotel Ortigia, which is a 5-star luxury hotel overlooking the harbor. It is just a short stroll to the must-see landmarks such as the ruins of the Temple of Apollo, the Aretusa Fountain, and the renowned Cathedral of Syracuse. it was built in 1890 and was completely renovated while preserving its classic old-world charm with marble floors, Corinthian columns, and beautiful art-filled common areas. They have an upscale rooftop restaurant and lounge on the third floor, which serves a sumptuous breakfast buffet and has great outdoor seating with spectacular views. I went up to the terrace one evening to enjoy the sunset with an Aperol Spritz and some nibbles and, after the sun went down, an exceptionally talented young man beautifully played his violin serenading the guests. Parking in the old city is a challenge, and not for the faint of heart. But the hotel does have a small lot nearby, but which seemed to stay full and was hard to find. With the helpful staff, I was able to register my rental car to allow me to drive to hotel which is in the restricted tourist zone and I moved my car to their lot one evening once the crowds had dissipated a bit. The staff couldn’t have been more helpful and even helped arrange a small group boat tour. This hotel truly deserves its name the Grand Hotel Ortigia Siracusa!"

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Ortygia Business Hotels

Our top choices for Ortygia business-friendly hotels

1. Algila' Ortigia Charme Hotel

2. Grand Hotel Ortigia Siracusa

3. Dimore delle Zagare Ortigia

4. Grand Hotel Des Ètrangers - The Leading Hotels of the World

5. Hotel Posta

6. CinqueSuites Ortigia

7. Ortea Palace Hotel, Sicily, Autograph Collection

8. Domus Mariae Albergo

9. L'Approdo delle Sirene

10. Domus Mariae Benessere

Top Ortygia Hotel Reviews

Algila' Ortigia Charme Hotel

Grand Hotel Ortigia Siracusa

Ortea Palace Hotel, Sicily, Autograph Collection

Domus Mariae Albergo

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