Hotels near Missouri Institute of Natural Science

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
28 Dec - 29 Dec
Tomorrow
29 Dec - 30 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Missouri Institute of Natural Science hotels

Free daily buffet breakfast
Holiday Inn Express and Suites Springfield Medical District by IHG

Holiday Inn Express and Suites Springfield Medical District by IHG

Holiday Inn Express and Suites Springfield Medical District by IHG
3.0 star property
4.6 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (955)
"Very clean, courteous staff, good breakfast!"
United States
Jason
The price is RM450
RM510 total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express and Suites Springfield Medical District by IHG
Terrace/patio
Homewood Suites by Hilton Springfield Medical District

Homewood Suites by Hilton Springfield Medical District

Homewood Suites by Hilton Springfield Medical District
3.0 star property
5.5 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (462)
"Beautiful room and very friendly staff"
United States
Amanda
The price is RM472
RM535 total
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton Springfield Medical District
Lobby lounge
Hampton Inn Springfield-South

Hampton Inn Springfield-South

Hampton Inn Springfield-South
2.5 star property
Galloway Village, 8.1 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (614)
"Breakfast and bed great."
United States
Gregory
The price is RM395
RM449 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Springfield-South
In-room safe, desk, iron/ironing board, free WiFi
Candlewood Suites Springfield-Medical District

Candlewood Suites Springfield-Medical District

Candlewood Suites Springfield-Medical District
2.5 star property
5.5 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (410)
"Clean room. Close to everything. Will book again. "
United States
Brian
The price is RM409
RM464 total
includes taxes & fees
11 Jan - 12 Jan 2026
Candlewood Suites Springfield-Medical District
Property amenity
Residence Inn by Marriott Springfield

Residence Inn by Marriott Springfield

Residence Inn by Marriott Springfield
3.0 star property
6.1 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (958)
"Amazing breakfast"
Spain
ROSA
The price is RM479
RM543 total
includes taxes & fees
31 Dec - 1 Jan 2026
Residence Inn by Marriott Springfield
Individually decorated, individually furnished, iron/ironing board
Walnut Street Inn

Walnut Street Inn

Walnut Street Inn
3.5 star property
Walnut Street, 11.9 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (209)
"Loved our stay here!"
United States
Mary
The price is RM456
RM517 total
includes taxes & fees
7 Jan - 8 Jan 2026
Walnut Street Inn
Front of property
TownePlace Suites Springfield

TownePlace Suites Springfield

TownePlace Suites Springfield
3.0 star property
Seminole Holland, 9.2 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (605)
"Great place to stay"
United States
Amy
The price is RM452
RM513 total
includes taxes & fees
19 Jan - 20 Jan 2026
TownePlace Suites Springfield
Lobby sitting area
Bass Pro Shops Angler's Lodge

Bass Pro Shops Angler's Lodge

Bass Pro Shops Angler's Lodge
2.5 star property
Fassnight, 8.9 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (1968)
"Exceptional room and service!!"
United States
april
The price is RM419
RM476 total
includes taxes & fees
30 Dec - 31 Dec
Bass Pro Shops Angler's Lodge
Lobby
Tru by Hilton Springfield Downtown

Tru by Hilton Springfield Downtown

Tru by Hilton Springfield Downtown
2.5 star property
Downtown Springfield, 11.6 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (899)
"Comfy bed .. good breakfast "
United States
Page
The price is RM428
RM489 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton Springfield Downtown
Front of property
Hilton Garden Inn Springfield, MO

Hilton Garden Inn Springfield, MO

Hilton Garden Inn Springfield, MO
3.0 star property
7.6 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (822)
"The staff was so accommodating, kind and amazing. We stayed over Christmas and had a great experience. "
United States
Wilson
The price is RM438
RM502 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Garden Inn Springfield, MO
Premium bedding, in-room safe, blackout curtains, iron/ironing board
Hotel Vandivort

Hotel Vandivort

Hotel Vandivort
4.0 star property
Downtown Springfield, 11.7 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (1003)
"Great place! Close to lots of stuff to do."
United States
Charles
The price is RM651
RM742 total
includes taxes & fees
29 Dec - 30 Dec
Hotel Vandivort
Exterior
Holiday Inn Express & Suites Springfield North by IHG

Holiday Inn Express & Suites Springfield North by IHG

Holiday Inn Express & Suites Springfield North by IHG
2.5 star property
17.1 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (1008)
"The room was clean and in a very quiet area, we slept well."
United States
ALFRED
The price is RM360
RM409 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Springfield North by IHG
Lobby
Hampton Inn Springfield-Southeast

Hampton Inn Springfield-Southeast

Hampton Inn Springfield-Southeast
2.5 star property
Galloway Village, 10.6 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (801)
"Very nice hotel. Clean and friendly staff. Very pet friendly."
United States
Maria
The price is RM415
RM471 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Springfield-Southeast
Lobby
MainStay Suites Springfield South - Battlefield Rd

MainStay Suites Springfield South - Battlefield Rd

MainStay Suites Springfield South - Battlefield Rd
2.0 star property
Bradford Park, 7.9 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (82)
"Nice Hotel"
United States
Earl
The price is RM341
RM387 total
includes taxes & fees
4 Jan - 5 Jan 2026
MainStay Suites Springfield South - Battlefield Rd
Lobby
Element Springfield South

Element Springfield South

Element Springfield South
3.0 star property
Meador Park, 7.4 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (100)
"Very solid hotel, clean and very spacious "
United States
Landon
The price is RM462
RM524 total
includes taxes & fees
23 Jan - 24 Jan 2026
Element Springfield South
Lobby
SpringHill Suites by Marriott Springfield North

SpringHill Suites by Marriott Springfield North

SpringHill Suites by Marriott Springfield North
2.5 star property
Parkwood, 17.1 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (769)
"Nice hotel and good value"
United States
Robert
The price is RM393
RM460 total
includes taxes & fees
4 Jan - 5 Jan 2026
SpringHill Suites by Marriott Springfield North
Premium bedding, down duvets, pillow-top beds, in-room safe
La Quinta Inn & Suites by Wyndham Springfield South

La Quinta Inn & Suites by Wyndham Springfield South

La Quinta Inn & Suites by Wyndham Springfield South
3.0 star property
Seminole Holland, 7.6 km from Missouri Institute of Natural Science
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay"
United States
Frank
The price is RM340
RM394 total
includes taxes & fees
1 Jan - 2 Jan 2026
La Quinta Inn & Suites by Wyndham Springfield South
Meeting facility
Culture Boutique Hotel

Culture Boutique Hotel

Culture Boutique Hotel
3.0 star property
14.2 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (290)
"Staff is phenomenal! Great communicators. This is our home away from home. Very comfortable. Always a pleasant experience. "
United States
Terry
Culture Boutique Hotel
Terrace/patio
Fairfield Inn & Suites by Marriott Springfield North

Fairfield Inn & Suites by Marriott Springfield North

Fairfield Inn & Suites by Marriott Springfield North
2.5 star property
Doling, 16.1 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (720)
"Great stay"
United States
christine
The price is RM442
RM508 total
includes taxes & fees
2 Jan - 3 Jan 2026
Fairfield Inn & Suites by Marriott Springfield North
Property amenity
Best Western Plus Springfield Airport Inn

Best Western Plus Springfield Airport Inn

Best Western Plus Springfield Airport Inn
2.5 star property
12.4 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (1000)
"Staff was really nice, shuttle driver was great, really helpful."
United States
Idania
The price is RM448
RM508 total
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus Springfield Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Missouri Institute of Natural Science Hotel Reviews

MainStay Suites Springfield South - Battlefield Rd

MainStay Suites Springfield South - Battlefield Rd

10/10 Excellent
"This is a great hotel tucked away off Battlefield. Have stayed several times and its always nice"
Ben 1-night trip
Posted 3 weeks ago
MainStay Suites Springfield South - Battlefield Rd
Extended Stay America Select Suites - Springfield - South - Battlefield

Extended Stay America Select Suites - Springfield - South - Battlefield

10/10 Excellent
"I stayed there a few times and they were home that I last had was the best room and the softest bed. I was very pleased."
Darrell 1-night trip
Posted 2 months ago
Extended Stay America Select Suites - Springfield - South - Battlefield

Hotels near other Missouri Institute of Natural Science attractions

Trail of Tears Park

After visiting Trail of Tears Park, make a plan to see the other sights and activities in Battlefield.
See properties

Trail of Tears National Historic Trail

You can take time to visit Trail of Tears National Historic Trail during your travels to Springfield. Experience the entertainment choices or attend a sporting event in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Missouri Institute of Natural Science?
Missouri Institute of Natural Science is located in Springfield. This family-friendly area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 5 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Missouri Institute of Natural Science?
Sleep Inn Springfield South I60 near Medical District is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located 2.7 mi (4.4 km) from Missouri Institute of Natural Science. Other good choices within a few miles include Quality Inn & Suites and Extended Stay America Select Suites - Springfield - South - Battlefield.
How many hotels are there close to Missouri Institute of Natural Science?
Expedia has 5 hotels and other accommodation options within a mile from Missouri Institute of Natural Science.
If I need to cancel the hotel reservation for my stay near Missouri Institute of Natural Science, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals available near Missouri Institute of Natural Science.
What can I see and do near Missouri Institute of Natural Science?
You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden. You might plan a visit to Trail of Tears National Historic Trail or Rivercut Golf Course while you're in the area. If you want to see more of the surrounding area, you can plan a visit to Ray House and Nixa City Hall.