Hotels near Mississippi River

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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (363 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
United States
Brent
The price is RM314
RM356 total
includes taxes & fees
11 May - 12 May
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (23 reviews)
"Best place to stay in town!"
United States
Kimberly
The price is RM375
RM426 total
includes taxes & fees
16 May - 17 May
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (763 reviews)
"the staff was Great!!"
United States
Karen Kay
The price is RM264
RM307 total
includes taxes & fees
11 May - 12 May
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,013 reviews)
"Super clean room Hot tub was amazing "
Canada
Paul
The price is RM431
RM497 total
includes taxes & fees
12 May - 13 May
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (172 reviews)
"Great place to stay!"
United States
Sandy
The price is RM586
RM812 total
includes taxes & fees
11 May - 12 May
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,002 reviews)
"Room was great and breakfast was fantastic "
United States
Sheila
The price is RM485
RM564 total
includes taxes & fees
17 May - 18 May
Sleep Inn & Suites Hannibal West

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,004 reviews)
"Property is most definitely dated. Linens were clean and comfortable for a night."
United States
Ashley
The price is RM280
RM330 total
includes taxes & fees
31 May - 1 Jun
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
9.0 out of 10, Wonderful, (27 reviews)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is RM704
RM812 total
includes taxes & fees
11 May - 12 May
Lighthouse Inn & Suites

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (533 reviews)
"If you're just looking for a place to stay for a few days it's ok, However the decor is old and outdated"
United States
Nicko
The price is RM274
RM311 total
includes taxes & fees
11 May - 12 May
Economy Inn Wentzville

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (690 reviews)
"Beds comfortable- nice breakfast choices. A pleasant peaceful setting "
United States
Wanda J
The price is RM363
RM430 total
includes taxes & fees
7 Jun - 8 Jun
Comfort Inn & Suites - Hannibal

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.8 out of 10, (1,003 reviews)
"What I liked about the property is that it’s affordable, with comfort to make you feel like your at home."
United States
Tamerra
The price is RM247
RM284 total
includes taxes & fees
11 May - 12 May
Relax Inn Saint Charles

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very good, (43 reviews)
"Very welcoming hosts, they went the extra mile and had a very comfortable bed! There were lots of cool antiques and they knew a lot of history on the home itself. We would recommend staying here again. "
United States
Andy Nicole
The price is RM420
RM484 total
includes taxes & fees
17 May - 18 May
Garden House Bed and Breakfast

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,003 reviews)
"Great stay with no issues at all."
Canada
Thomas
The price is RM255
RM294 total
includes taxes & fees
25 May - 26 May
Motel 6 Hannibal, MO

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (236 reviews)
"Nice room and great location. Well maintained. Economy choice."
United States
Edward
The price is RM247
RM285 total
includes taxes & fees
27 May - 28 May
Days Inn by Wyndham Hannibal

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,012 reviews)
"Great property, good breakfast. "
United States
Bree
The price is RM335
RM390 total
includes taxes & fees
17 May - 18 May
Quality Inn & Suites Hannibal West

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (510 reviews)
"I would book this same hotel again . It’s older, but very accommodating. "
United States
Michael
The price is RM328
RM368 total
includes taxes & fees
11 May - 12 May
Baymont by Wyndham Keokuk

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,002 reviews)
"Property was clean and staff was friendly."
United States
Etta
The price is RM254
RM293 total
includes taxes & fees
17 May - 18 May
Super 8 by Wyndham Hannibal

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (47 reviews)
"Good"
United States
Krischel
The price is RM265
RM299 total
includes taxes & fees
17 May - 18 May
LAKEVIEWINN

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (166 reviews)
"The room was clean . The staff was helpful on things to do in the area. It was a very relaxing and the town was beautiful"
United States
Samantha
The price is RM250
RM290 total
includes taxes & fees
11 May - 12 May
Howard Johnson BY Wyndham Hannibal

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,009 reviews)
"Great stay"
United States
Micaela
The price is RM297
RM363 total
includes taxes & fees
25 May - 26 May
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
363 reviews
View
Lunch and dinner served, Italian cuisine
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
23 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
763 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,013 reviews
View
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
172 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveller data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Pear Tree Inn St. Louis Airport.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.