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Hotels near Mississippi River
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Our top choices for Mississippi River hotels

River's Edge Motel
River's Edge Motel13.6 km from Mississippi River
9.0 out of 10, Wonderful, (361 reviews)
The price is RM316
RM359 total
includes taxes & fees
26 Mar - 27 Mar

The Eagles Nest Inn
The Eagles Nest Inn14.2 km from Mississippi River
9.4 out of 10, Exceptional, (22 reviews)
The price is RM378
RM429 total
includes taxes & fees
29 Mar - 30 Mar

Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal26.3 km from Mississippi River
6.4 out of 10, (746 reviews)
The price is RM249
RM288 total
includes taxes & fees
26 Mar - 27 Mar

Best Western On The River
Best Western On The River25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,002 reviews)
The price is RM427
RM491 total
includes taxes & fees
29 Mar - 30 Mar

Riverside Inn Hannibal
Riverside Inn Hannibal25.1 km from Mississippi River
9.4 out of 10, Exceptional, (170 reviews)
The price is RM563
RM783 total
includes taxes & fees
28 Mar - 29 Mar

Super 8 by Wyndham O'Fallon MO/St. Louis Area
Super 8 by Wyndham O'Fallon MO/St. Louis Area90.7 km from Mississippi River
6.8 out of 10, (1,001 reviews)
The price is RM269
RM317 total
includes taxes & fees
19 Apr - 20 Apr

Sleep Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
The price is RM459
RM532 total
includes taxes & fees
5 Apr - 6 Apr

Economy Inn Wentzville
Economy Inn Wentzville86.8 km from Mississippi River
6.4 out of 10, (521 reviews)
The price is RM237
RM269 total
includes taxes & fees
26 Mar - 27 Mar

Days Inn by Wyndham St Peters/St Charles
Days Inn by Wyndham St Peters/St Charles93.8 km from Mississippi River
6.2 out of 10, (1,000 reviews)
The price is RM266
RM305 total
includes taxes & fees
19 Apr - 20 Apr

Lighthouse Inn & Suites
Lighthouse Inn & Suites25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
The price is RM668
RM903 total
includes taxes & fees
26 Mar - 27 Mar

Garden House Bed and Breakfast
Garden House Bed and Breakfast25.2 km from Mississippi River
8.4 out of 10, Very good, (40 reviews)
The price is RM381
RM438 total
includes taxes & fees
12 Apr - 13 Apr

LAKEVIEWINN
LAKEVIEWINN89.4 km from Mississippi River
5.8 out of 10, (39 reviews)
The price is RM267
RM302 total
includes taxes & fees
26 Mar - 27 Mar

Baymont by Wyndham Keokuk
Baymont by Wyndham Keokuk96.1 km from Mississippi River
6.2 out of 10, (500 reviews)
The price is RM249
RM279 total
includes taxes & fees
29 Mar - 30 Mar

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North109.6 km from Mississippi River
6.6 out of 10, (1,005 reviews)
The price is RM276
RM337 total
includes taxes & fees
5 Apr - 6 Apr

Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal26.2 km from Mississippi River
7.6 out of 10, Good, (679 reviews)
The price is RM357
RM422 total
includes taxes & fees
29 Mar - 30 Mar

Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal26.3 km from Mississippi River
7.2 out of 10, Good, (1,002 reviews)
The price is RM231
RM266 total
includes taxes & fees
29 Mar - 30 Mar

Motel 6 Hannibal, MO
Motel 6 Hannibal, MO26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
The price is RM221
RM254 total
includes taxes & fees
28 Mar - 29 Mar

Quality Inn & Suites Hannibal West
Quality Inn & Suites Hannibal West30 km from Mississippi River
8.0 out of 10, Very good, (1,009 reviews)
The price is RM318
RM368 total
includes taxes & fees
5 Apr - 6 Apr

Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal26.4 km from Mississippi River
7.4 out of 10, Good, (227 reviews)
The price is RM252
RM290 total
includes taxes & fees
30 Mar - 31 Mar

Sleep Inn Saint Charles North
Sleep Inn Saint Charles North97.1 km from Mississippi River
5.8 out of 10, (525 reviews)
The price is RM289
RM332 total
includes taxes & fees
16 Apr - 17 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Mississippi River
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() River's Edge Motel | 9.0 Wonderful 361 reviews | View | ||||||
![]() The Eagles Nest Inn | 9.4 Exceptional 22 reviews | View | ||||||
![]() Baymont by Wyndham Hannibal | 6.4 746 reviews | View | ||||||
![]() Best Western On The River | 8.6 Excellent 1,002 reviews | View | ||||||
![]() Riverside Inn Hannibal | 9.4 Exceptional 170 reviews | View |
Top Mississippi River Hotel Reviews

Drury Inn & Suites St. Louis Union Station
10/10 Excellent








































































