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Hotels near Mississippi River

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Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

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Our top choices for Mississippi River hotels

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

1. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Great stay- within walking distance of good restaurant and coffee shop. Breakfast included hot items with adequate seating."
United States
ELAINE
The price is RM436
RM507 total
includes taxes & fees
25 Nov - 26 Nov
Sleep Inn & Suites Hannibal West
A restaurant with a bar area, wooden flooring, checkered tablecloths, and a brick wall.

2. The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.6 out of 10, Exceptional, (28 reviews)
"Cutest place to stay in Louisiana Missouri"
United States
Kimberly
The price is RM478
RM543 total
includes taxes & fees
1 Nov - 2 Nov
The Eagles Nest Inn
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

3. Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.8 out of 10, Excellent, (1,000 reviews)
"fun town to stay and visit"
United States
Wei
The price is RM482
RM556 total
includes taxes & fees
9 Nov - 10 Nov
Best Western On The River
A gazebo with a table and benches, surrounded by trees and a body of water.

4. River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
8.8 out of 10, Excellent, (394 reviews)
"Parking, noise from A/C. View was nice, just ok for over night."
United States
Joseph
The price is RM360
RM408 total
includes taxes & fees
29 Oct - 30 Oct
River's Edge Motel
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

5. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.6 out of 10, Exceptional, (204 reviews)
"Very nice room and great view of the river. Very comfortable bed and very nice shower. Walking distance to so many restaurants and shops. We enjoyed our stay very much!"
United States
Christina
The price is RM620
RM857 total
includes taxes & fees
9 Nov - 10 Nov
Riverside Inn Hannibal
A hotel room with a bed, desk, television, and a patterned carpet.

6. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,008 reviews)
"Our go to hotel for years when we visit Hannibal."
United States
Gayle
The price is RM327
RM381 total
includes taxes & fees
25 Nov - 26 Nov
Quality Inn & Suites Hannibal West
A hotel room with a bed, a desk with a lamp, a television, and a bathroom with a sink and mirror.

7. Oak Hill Inn & Suites

Oak Hill Inn & Suites
2.5 star property
71.8 km from Mississippi River
9.2 out of 10, Wonderful, (1,008 reviews)
"It’s a great place to spend the night."
United States
Regina
The price is RM414
RM472 total
includes taxes & fees
1 Nov - 2 Nov
Oak Hill Inn & Suites
A modern kitchen with wooden cabinets, a granite countertop, a coffee machine, a microwave, a toaster, and a refrigerator.

8. Heritage Hotel Quincy

Heritage Hotel Quincy
2.0 star property
47.8 km from Mississippi River
8.6 out of 10, Excellent, (475 reviews)
"The rooms are newly renovated."
United States
Amy
The price is RM318
RM363 total
includes taxes & fees
1 Nov - 2 Nov
Heritage Hotel Quincy
A hotel room with a bed, a sofa, a desk, and a lamp.

9. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (767 reviews)
"Front desk helpful Clean rooms Great breakfast and lady fixing our breakfast was helpful and kept plenty of food ready for all"
United States
Jerry
The price is RM324
RM386 total
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn & Suites - Hannibal
A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

10. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,004 reviews)
"Excellent place to stay"
United States
Jared
The price is RM237
RM273 total
includes taxes & fees
1 Nov - 2 Nov
Motel 6 Hannibal, MO
A hot tub with a rocky backdrop and a mural.

11. Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
2.0 star property
46.5 km from Mississippi River
8.6 out of 10, Excellent, (1,001 reviews)
"The hotel was rustic, clean, and a great place to stay."
United States
Kent
The price is RM399
RM455 total
includes taxes & fees
1 Nov - 2 Nov
Stoney Creek Inn Quincy
A hotel room with two beds, a wooden headboard, a nightstand with a phone, and a wall-mounted lamp.

12. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (294 reviews)
"Pretty good place to stay at with a great price !!"
United States
Christian
The price is RM261
RM301 total
includes taxes & fees
11 Nov - 12 Nov
Days Inn by Wyndham Hannibal
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

13. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (47 reviews)
"The room was very clean. It had a hot tub in it and it was also very clean and worked properly. We enjoyed our stay there."
United States
Connie
The price is RM651
RM893 total
includes taxes & fees
29 Oct - 30 Oct
Lighthouse Inn & Suites
A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

14. Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,004 reviews)
"Clean, safe hotel and friendly staff"
United States
Julie
The price is RM252
RM291 total
includes taxes & fees
1 Nov - 2 Nov
Super 8 by Wyndham Hannibal
A hotel room with a bed, a desk with a computer, a TV, and a bathroom with a shower.

15. Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
2.5 star property
47.8 km from Mississippi River
8.8 out of 10, Excellent, (498 reviews)
"Great stay for a wedding in the area."
United States
Bryan
The price is RM488
RM557 total
includes taxes & fees
26 Nov - 27 Nov
Quality Inn & Suites Quincy - Downtown
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.

16. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
3.0 star property
46.1 km from Mississippi River
8.8 out of 10, Excellent, (696 reviews)
"The hotel was in a great location with clean rooms."
United States
Colleen
The price is RM487
RM555 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Quincy East by IHG
A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

17. Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (187 reviews)
"Great price! Nice comfortable clean room"
United States
Debbie
The price is RM246
RM286 total
includes taxes & fees
2 Nov - 3 Nov
Howard Johnson BY Wyndham Hannibal
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

18. DoubleTree by Hilton Quincy

DoubleTree by Hilton Quincy
3.5 star property
47.9 km from Mississippi River
8.4 out of 10, Very good, (786 reviews)
"Rooms were very clean and the staff was amazing and very accommodating for all of our family. There were 10 different families and they made sure we were all in the same floor."
United States
Ronda
The price is RM465
RM530 total
includes taxes & fees
15 Nov - 16 Nov
DoubleTree by Hilton Quincy
A hotel room with a bed, a desk, a chair, a television, and a window with curtains.

19. Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area
2.5 star property
47.9 km from Mississippi River
7.6 out of 10, Good, (1,002 reviews)
"Nice place. Convenient location."
United States
Robert
The price is RM313
RM356 total
includes taxes & fees
3 Nov - 4 Nov
Microtel Inn & Suites by Wyndham Quincy Downtown/River Area
A hotel lobby with a dining area, a bar, and a fireplace.

20. Fairfield Inn & Suites Quincy

Fairfield Inn & Suites Quincy
3.0 star property
46 km from Mississippi River
8.6 out of 10, Excellent, (364 reviews)
"Room was clean, the breakfast buffet had a lot options."
United States
Chris
The price is RM483
RM550 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites Quincy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Mississippi River

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

Sleep Inn & Suites Hannibal West

2.5 star property
30.3 km from Mississippi River
View
A restaurant with a bar area, wooden flooring, checkered tablecloths, and a brick wall.

The Eagles Nest Inn

3.0 star property
14.2 km from Mississippi River
View
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

Best Western On The River

2.5 star property
25.3 km from Mississippi River
View
A gazebo with a table and benches, surrounded by trees and a body of water.

River's Edge Motel

2.0 star property
13.6 km from Mississippi River
View
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

Riverside Inn Hannibal

2.5 star property
25.1 km from Mississippi River
View
9.6
Exceptional
1,001 reviews
9.6
Exceptional
28 reviews
8.8
Excellent
1,000 reviews
8.8
Excellent
394 reviews
9.6
Exceptional
204 reviews
The price is RM436
RM507 total
includes taxes & fees
25 Nov - 26 Nov
The price is RM478
RM543 total
includes taxes & fees
1 Nov - 2 Nov
The price is RM482
RM556 total
includes taxes & fees
9 Nov - 10 Nov
The price is RM360
RM408 total
includes taxes & fees
29 Oct - 30 Oct
The price is RM620
RM857 total
includes taxes & fees
9 Nov - 10 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • No WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families near Mississippi River

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,001)
The price is RM409
RM461 total
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel Cape Girardeau Conference Center

Top Mississippi River Hotel Reviews

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"I liked everything"
Jonathan 1-night trip
Posted 10 hours ago
Renaissance St. Louis Airport Hotel

Other attractions near Mississippi River

Mark Twain Cave

8.8/10 (89 reviews)
You can find out about the history of Hannibal with a visit to Mark Twain Cave. While in this trendy area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveller data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.