Hotels near Mississippi River

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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (361 reviews)
"Staff was really nice and helpful."
United States
rhonda
The price is RM316
RM359 total
includes taxes & fees
26 Mar - 27 Mar
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (22 reviews)
"Best place to stay in town!"
United States
Kimberly
The price is RM378
RM429 total
includes taxes & fees
29 Mar - 30 Mar
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (746 reviews)
"Great"
United States
Gregory
The price is RM249
RM288 total
includes taxes & fees
26 Mar - 27 Mar
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,002 reviews)
"Stayed in their annex building . Quiet and very nice fixtures and quality of the furniture, etc."
United States
Tracy
The price is RM427
RM491 total
includes taxes & fees
29 Mar - 30 Mar
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (170 reviews)
"Great place to stay!"
United States
Sandy
The price is RM563
RM783 total
includes taxes & fees
28 Mar - 29 Mar
Riverside Inn Hannibal

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"Good stay. "
United States
Ted
The price is RM269
RM317 total
includes taxes & fees
19 Apr - 20 Apr
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Would highly recommend to anyone needed an excellent hotel"
United States
Elizabeth
The price is RM459
RM532 total
includes taxes & fees
5 Apr - 6 Apr
Sleep Inn & Suites Hannibal West

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (521 reviews)
"Really cozy place to stay at!"
United States
Yufei
The price is RM237
RM269 total
includes taxes & fees
26 Mar - 27 Mar
Economy Inn Wentzville

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,000 reviews)
"Everything was good "
United States
Carol
The price is RM266
RM305 total
includes taxes & fees
19 Apr - 20 Apr
Days Inn by Wyndham St Peters/St Charles

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is RM668
RM903 total
includes taxes & fees
26 Mar - 27 Mar
Lighthouse Inn & Suites

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very good, (40 reviews)
"Very welcoming hosts, they went the extra mile and had a very comfortable bed! There were lots of cool antiques and they knew a lot of history on the home itself. We would recommend staying here again. "
United States
Andy Nicole
The price is RM381
RM438 total
includes taxes & fees
12 Apr - 13 Apr
Garden House Bed and Breakfast

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.8 out of 10, (39 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is RM267
RM302 total
includes taxes & fees
26 Mar - 27 Mar
LAKEVIEWINN

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (500 reviews)
"Ok stay"
United States
Timothy
The price is RM249
RM279 total
includes taxes & fees
29 Mar - 30 Mar
Baymont by Wyndham Keokuk

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,005 reviews)
"Enjoy our stay very nice clean neat breakfast fresh and staff helpful and pleasant "
United States
Tatiana
The price is RM276
RM337 total
includes taxes & fees
5 Apr - 6 Apr
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (679 reviews)
"The front desk woman was so helpful and kind. The location was extremely clean, the breakfast was honestly one of the best I have had for a free continental breakfast, and I loved the hot tub. I felt very safe. Beds were comfortable. Great location. "
United States
Kayleigh
The price is RM357
RM422 total
includes taxes & fees
29 Mar - 30 Mar
Comfort Inn & Suites - Hannibal

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,002 reviews)
"Clean rooms, easy check in, friendly staff, awesome location "
United States
Rhonda
The price is RM231
RM266 total
includes taxes & fees
29 Mar - 30 Mar
Super 8 by Wyndham Hannibal

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
"Great stay with no issues at all."
Canada
Thomas
The price is RM221
RM254 total
includes taxes & fees
28 Mar - 29 Mar
Motel 6 Hannibal, MO

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,009 reviews)
"Great stay. Very comfortable beds!"
United States
Kari
The price is RM318
RM368 total
includes taxes & fees
5 Apr - 6 Apr
Quality Inn & Suites Hannibal West

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (227 reviews)
"The room was clean. The staff were courteous. Breakfast was poor. "
United States
Helen
The price is RM252
RM290 total
includes taxes & fees
30 Mar - 31 Mar
Days Inn by Wyndham Hannibal

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (525 reviews)
"Listing was completely false there is no pool that will ever be operational supposed to be a suite that sleeps 4 but hide a bed had no bedding and when I asked for some all they would give me was 2 very old thin blankets no sheet no pillow both the other beds were stained and dirty there was no toilet paper windows were boarded up on building and was just not what they represented online "
United States
Levi
The price is RM289
RM332 total
includes taxes & fees
16 Apr - 17 Apr
Sleep Inn Saint Charles North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
361 reviews
View
Interior
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
22 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
746 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,002 reviews
View
Egyptian cotton sheets, premium bedding, pillow-top beds
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
170 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveller data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Pear Tree Inn St. Louis Near Union Station and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.