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Hotels in Middletown, San Diego

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7 Dec - 8 Dec
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Top 10 Hotels in Middletown, San Diego

Exterior
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

4.5 star property
Middletown
9.6 out of 10, Exceptional, (104)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
2.3 km from Middletown
8.4 out of 10, Very good, (6073)
"Always an amazing stay"
United States
Jana
The price is RM556
RM764 total
includes taxes & fees
10 Dec - 11 Dec
Wyndham San Diego Bayside
2 outdoor pools, a heated pool, pool loungers
The Dana on Mission Bay

The Dana on Mission Bay

3.5 star property
Mission Bay, 6.5 km from Middletown
9.0 out of 10, Wonderful, (3907)
"Staff was great, room was spotless, and map was easy to follow."
United States
Rosa
The price is RM613
RM787 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Dana on Mission Bay
Terrace/patio
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 star property
2.2 km from Middletown
8.8 out of 10, Excellent, (1273)
"Spacious and clean rooms, helpful staff"
United States
Gholam
The price is RM415
RM476 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn San Diego/Mission Valley
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

4.0 star property
2.7 km from Middletown
8.6 out of 10, Excellent, (1050)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is RM556
RM764 total
includes taxes & fees
19 Dec - 20 Dec
The Westin San Diego Bayview
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
2.8 km from Middletown
8.6 out of 10, Excellent, (1444)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego
Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
2.2 km from Middletown
8.8 out of 10, Excellent, (718)
"Great staff, great location, great value. "
United States
Juan
The price is RM424
RM492 total
includes taxes & fees
15 Dec - 16 Dec
The DEXTRO Little Italy, BW Premier Collection
Lobby
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
Marina District, 3.2 km from Middletown
9.0 out of 10, Wonderful, (1539)
"Clean room, friendly staff, great property. "
United States
MIGUEL
The price is RM681
RM939 total
includes taxes & fees
23 Dec - 24 Dec
Embassy Suites by Hilton San Diego Bay Downtown
Property grounds
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4.0 star property
Mission Bay, 7.1 km from Middletown
8.6 out of 10, Excellent, (2348)
"Amazing place!"
United States
Barak Ben
The price is RM532
RM829 total
includes taxes & fees
10 Dec - 11 Dec
Paradise Point Resort & Spa
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
2.2 km from Middletown
9.2 out of 10, Wonderful, (2955)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
The price is RM626
RM719 total
includes taxes & fees
8 Dec - 9 Dec
Legacy Resort Hotel & Spa
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
Marina District, 3.5 km from Middletown
9.2 out of 10, Wonderful, (1939)
"Great hotel"
United States
Farzana
The price is RM654
RM974 total
includes taxes & fees
18 Dec - 19 Dec
Marriott Marquis San Diego Marina
In-room safe, desk, blackout curtains, iron/ironing board
Bahia Resort Hotel

Bahia Resort Hotel

3.5 star property
Central Mission Beach, 7.6 km from Middletown
8.6 out of 10, Excellent, (1806)
"Staff was very friendly hotel was very very clean! "
United States
Antonio
The price is RM523
RM830 total
includes taxes & fees
5 Jan - 6 Jan 2026
Bahia Resort Hotel
Outdoor pool, pool loungers
Hyatt Regency La Jolla

Hyatt Regency La Jolla

4.0 star property
15.3 km from Middletown
8.8 out of 10, Excellent, (1005)
"Clean rooms, excellent staff and Drift restaurant is also very nice "
United States
Paresh
The price is RM591
RM831 total
includes taxes & fees
14 Dec - 15 Dec
Hyatt Regency La Jolla
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 star property
5.4 km from Middletown
9.2 out of 10, Wonderful, (3172)
"Great stay and location!"
United States
Jason
The price is RM440
RM506 total
includes taxes & fees
8 Dec - 9 Dec
Bay Club Hotel & Marina
Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
10.8 km from Middletown
9.2 out of 10, Wonderful, (3494)
"Clean room nice staff right off of the freeway. "
United States
Olivia
The price is RM477
RM526 total
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Marina Gateway Hotel
City view from property
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4.0 star property
Little Italy, 2.1 km from Middletown
9.0 out of 10, Wonderful, (78)
"It was a nice place to stay at"
United States
Eric
The price is RM452
RM524 total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott San Diego Downtown Little Italy
Lobby
Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection

4.0 star property
2.6 km from Middletown
9.0 out of 10, Wonderful, (1181)
"Amazing stay "
United States
Aaron
The price is RM584
RM868 total
includes taxes & fees
29 Dec - 30 Dec
Hotel Republic San Diego, Autograph Collection
Daily buffet breakfast for a fee
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4.0 star property
3.6 km from Middletown
8.4 out of 10, Very good, (1388)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is RM469
RM539 total
includes taxes & fees
14 Dec - 15 Dec
DoubleTree by Hilton Hotel San Diego - Mission Valley
Outdoor pool, pool loungers
Inn By The Sea La Jolla

Inn By The Sea La Jolla

3.5 star property
15.1 km from Middletown
9.4 out of 10, Exceptional, (1731)
"excellent location, service and amennities"
United States
leo
The price is RM618
RM710 total
includes taxes & fees
21 Dec - 22 Dec
Inn By The Sea La Jolla
View from room
Catamaran Resort and Spa

Catamaran Resort and Spa

4.0 star property
Mission Beach, 9.2 km from Middletown
8.6 out of 10, Excellent, (1104)
"Amazing room, phenomenal staff, highly recommend! Favorite hotel in San Diego "
United States
Daniel
The price is RM589
RM897 total
includes taxes & fees
5 Jan - 6 Jan 2026
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Middletown

Find the best Middletown areas for the activities you enjoy most. Learn more about Middletown
Learn more about Middletown

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter showing night scenes, a bar and street scenes

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park showing a sandy beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park showing rides and a park

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Middletown Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"The room was pretty great there was a nice view of the town, but we could see homeless people in tents sleeping, so there was that. Front desk was amazing. The bar downstairs was great my husband went down and had a drink and watched some sports. Overall a great trip: for a three-star hotel, it was fantastic! Price of room was average, but the parking was a little much at $37.50 for one 24 hour peri[parking fr 9:00 p.m. to 5:00 a.m. was steep."
Jennifer 1-night trip
Posted 21 hours ago
The DEXTRO Little Italy, BW Premier Collection

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Middletown?
Middletown is a neighbourhood that travellers like for its live music, bars and theatres.
How many hotels can I expect to find in the Middletown area?
Expedia has 91 hotels and other accommodation options in Middletown to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Middletown, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to view top deals in Middletown.
What are the top things to see and do in Middletown?
Favourite places to visit in the surrounding area include San Diego Zoo, Hotel Circle and Port of San Diego. While you're out sightseeing, Petco Park and Marston House are a couple of additional sights to visit in San Diego.
How can I get around Middletown and the greater San Diego area?
Ready to get out and explore the city? Middletown Station is the closest metro station.