Hotels near Main Street

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Main Street hotels

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
9.6 km from Main Street
9.4 out of 10, Exceptional, (1,000 reviews)
"Staff member Sandy very congenial when we checked in. Laid back atmosphere (early December). Will consider for future Hyannis stay."
United States
Lawrence
The price is RM550
RM746 total
includes taxes & fees
14 Jan - 15 Jan
Anchor In Distinctive Waterfront Lodging

Sea Street Inn

Sea Street Inn
4.0 star property
8 km from Main Street
9.8 out of 10, Exceptional, (45 reviews)
"Adrian was an awesome host. Comfortable bed, safe area to walk, beautiful surroundings."
United States
Jori
The price is RM913
RM1,045 total
includes taxes & fees
11 Jan - 12 Jan
Sea Street Inn

Courtyard Resort

Courtyard Resort
2.0 star property
8.8 km from Main Street
8.4 out of 10, Very good, (50 reviews)
"Clean and inexpensive"
United States
Robert
The price is RM444
RM508 total
includes taxes & fees
19 Jan - 20 Jan
Courtyard Resort

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
9.2 km from Main Street
8.8 out of 10, Excellent, (490 reviews)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is RM517
RM591 total
includes taxes & fees
25 Jan - 26 Jan
Courtyard By Marriott Cape Cod Hyannis

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
10.7 km from Main Street
8.8 out of 10, Excellent, (1,000 reviews)
"They were excellent. Felt extremely comfortable. Their breakfast was amazing, staff were so friendly!"
United States
Linda
The price is RM473
RM542 total
includes taxes & fees
7 Feb - 8 Feb
Hampton Inn & Suites Cape Cod-West Yarmouth

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
8.9 km from Main Street
8.2 out of 10, Very good, (982 reviews)
"Nice place"
United States
Linda
The price is RM464
RM531 total
includes taxes & fees
14 Jan - 15 Jan
Holiday Inn Hyannis by IHG

Cape Cod Hotel

Cape Cod Hotel
2.5 star property
8.8 km from Main Street
7.4 out of 10, Good, (1,000 reviews)
"Great stay"
United States
Vanuze
The price is RM399
RM504 total
includes taxes & fees
17 Jan - 18 Jan
Cape Cod Hotel

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
10.9 km from Main Street
9.4 out of 10, Exceptional, (100 reviews)
"Clean, nice staff, good amenities, central location"
United States
Malbis
The price is RM566
RM648 total
includes taxes & fees
18 Jan - 19 Jan
Uncommoner Hotel by Reverie Boutique Collection

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
9.4 km from Main Street
8.0 out of 10, Very good, (1,000 reviews)
"Nice hotel had a perfect stay"
United States
David
The price is RM401
RM459 total
includes taxes & fees
29 Jan - 30 Jan
Comfort Inn Hyannis - Cape Cod

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
11.2 km from Main Street
8.8 out of 10, Excellent, (1,535 reviews)
"All the resort and staff was great!"
United States
Sandra
The price is RM402
RM507 total
includes taxes & fees
13 Jan - 14 Jan
Bayside Resort Hotel

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
8.7 km from Main Street
8.8 out of 10, Excellent, (427 reviews)
"We are very happy with all the people at margaritaville, they are awesome 💝"
United States
Ewerton
Margaritaville Resort Cape Cod

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
9.8 km from Main Street
8.4 out of 10, Very good, (882 reviews)
"Clean hotel, kind staff, the kids loved the warm indoor pool since it’s winter. All was good. "
United States
Tania
The price is RM461
RM528 total
includes taxes & fees
25 Jan - 26 Jan
Doubletree by Hilton Cape Cod - Hyannis

The Club at New Seabury

The Club at New Seabury
3.5 star property
10.3 km from Main Street
9.0 out of 10, Wonderful, (344 reviews)
"The place was excellent"
United States
Delia
The price is RM666
RM763 total
includes taxes & fees
18 Jan - 19 Jan
The Club at New Seabury

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
9.1 km from Main Street
8.0 out of 10, Very good, (1,000 reviews)
"Lovely stay! One of the best hotels to stay in Hyannis. "
United States
Mary
The price is RM502
RM739 total
includes taxes & fees
25 Jan - 26 Jan
Hyannis Harbor Hotel

The Village Inn Cape Cod

The Village Inn Cape Cod
3.5 star property
14.3 km from Main Street
10.0 out of 10, Exceptional, (223 reviews)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is RM753
RM862 total
includes taxes & fees
11 Jan - 12 Jan
The Village Inn Cape Cod

Cape Sands Inn

Cape Sands Inn
2.5 star property
11 km from Main Street
8.2 out of 10, Very good, (1,015 reviews)
"Clean room courteous staff and easy check in "
United States
Linda
The price is RM410
RM470 total
includes taxes & fees
13 Jan - 14 Jan
Cape Sands Inn

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
8.2 km from Main Street
7.0 out of 10, Good, (985 reviews)
"The best staff abd it was clean and beautiful "
United States
Heather
The price is RM338
RM427 total
includes taxes & fees
8 Feb - 9 Feb
Hyannis Plaza Hotel

Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth
3.0 star property
12.4 km from Main Street
8.0 out of 10, Very good, (1,001 reviews)
"Clean room | Breakfast | Bar | Staff"
United States
Daniel
The price is RM394
RM451 total
includes taxes & fees
20 Jan - 21 Jan
Aiden by Best Western Cape Cod - West Yarmouth

Harborside Suites

Harborside Suites
2.0 star property
15.1 km from Main Street
6.6 out of 10, (189 reviews)
"Nice hotel "
United States
Sergio
Harborside Suites

The Escape Inn

The Escape Inn
2.5 star property
16.5 km from Main Street
9.4 out of 10, Exceptional, (661 reviews)
"Great place"
United States
Karim
The price is RM327
RM374 total
includes taxes & fees
14 Jan - 15 Jan
The Escape Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Main Street Hotel Reviews

Hotels near other Main Street attractions

Frequently asked questions

What's the area like around Main Street?
If you're planning to come to the area to visit Main Street, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, take a look at the 23 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Main Street?
Long Dell Inn is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free parking. It's located 2.5 mi (4.1 km) from Main Street. Other good choices within 5 miles include Craigville Beach Inn and The Ocean View.
How many hotels will I be able to find near Main Street?
Expedia has 23 hotels and other accommodation options within a mile from Main Street.
If I need to cancel the hotel reservation for my stay near Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best options available near Main Street.
What can I see and do near Main Street?
Study the collections at Centerville Historical Museum, Cahoon Museum of American Art or Toad Hall Classic Sports Car Museum. You can check out the local talent at Cotuit Center for the Arts, Cape Cod Melody Tent and Barnstable Performing Arts Center. Dip your toes in the water at Craigville Beach, Keyes Beach and Dowses Beach.