Hotels in Lake Nona Medical City, Orlando

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lake Nona Medical City hotels

Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (379 reviews)
"Great hotel!"
United States
sammypsu
The price is RM550
RM625 total
includes taxes & fees
26 May - 27 May
Aloft by Marriott Orlando Lake Nona

Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (634 reviews)
"This is a great place to stay. Very clean, cute area, great restaurants close by."
United States
vida
The price is RM604
RM686 total
includes taxes & fees
31 May - 1 Jun
Courtyard Orlando Lake Nona

Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (335 reviews)
"All very decent. Would stay again if in Lake Nona Great location "
United States
Jasenka
The price is RM711
RM808 total
includes taxes & fees
24 May - 25 May
Residence Inn Orlando Lake Nona

Kompose Boutique Resort at Theme Parks

Kompose Boutique Resort at Theme Parks
3.0 star property
30.8 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4,072 reviews)
"The breakfast and pool was great"
United States
Emmanuelle
The price is RM110
RM301 total
includes taxes & fees
21 May - 22 May
Kompose Boutique Resort at Theme Parks

Universal's Terra Luna Resort

Universal's Terra Luna Resort
3.0 star property
18.9 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (648 reviews)
"Great hotel and very friendly staff. "
United States
Martyna
The price is RM538
RM605 total
includes taxes & fees
20 May - 21 May
Universal's Terra Luna Resort

Hyatt House Orlando International Drive

Hyatt House Orlando International Drive
4.0 star property
International Drive District, 20.2 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (1,825 reviews)
"Great place to stay"
United States
Idoel
The price is RM376
RM423 total
includes taxes & fees
31 May - 1 Jun
Hyatt House Orlando International Drive

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel
3.0 star property
International Drive District, 21.3 km from Lake Nona Medical City
8.6 out of 10, Excellent, (1,407 reviews)
"Excellent place to stay , come back "
United States
Jeannette
The price is RM336
RM378 total
includes taxes & fees
26 May - 27 May
DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport
3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.4 out of 10, Good, (1,976 reviews)
"Pretty good stay overall would come back for sure"
United States
Rahmel
The price is RM297
RM335 total
includes taxes & fees
11 Jun - 12 Jun
La Quinta Inn & Suites by Wyndham Orlando Airport

Wyndham Garden Orlando Airport

Wyndham Garden Orlando Airport
3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (4,067 reviews)
"Great place to stay. "
United States
scott
The price is RM315
RM354 total
includes taxes & fees
20 May - 21 May
Wyndham Garden Orlando Airport

Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
16.9 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4,802 reviews)
"Great golf resort , great food "
United States
David
The price is RM471
RM530 total
includes taxes & fees
27 May - 28 May
Rosen Shingle Creek

Orlando Palms Hotel

Orlando Palms Hotel
2.5 star property
14.9 km from Lake Nona Medical City
7.8 out of 10, Good, (2,824 reviews)
"Fantastic hotel at a fantastic price and location"
United States
Issac
The price is RM217
RM291 total
includes taxes & fees
21 May - 22 May
Orlando Palms Hotel

Fairfield Inn By Marriott Orlando Airport

Fairfield Inn By Marriott Orlando Airport
3.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,458 reviews)
"Breakfast was great and the airport shuttle was timely and pleasant"
United States
Cheryl
The price is RM326
RM366 total
includes taxes & fees
14 Jun - 15 Jun
Fairfield Inn By Marriott Orlando Airport

Vacation Village Orlando, Celebration

Vacation Village Orlando, Celebration
3.0 star property
25.4 km from Lake Nona Medical City
8.6 out of 10, Excellent, (4,163 reviews)
"Fanily friendly, great value, great location!"
United States
Marivette
The price is RM322
RM465 total
includes taxes & fees
24 May - 25 May
Vacation Village Orlando, Celebration

Margaritaville Resort Orlando with H2O Waterpark

Margaritaville Resort Orlando with H2O Waterpark
4.0 star property
32.8 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3,609 reviews)
"Clean room and very very nice staff."
United States
Natjaree
The price is RM568
RM861 total
includes taxes & fees
25 May - 26 May
Margaritaville Resort Orlando with H2O Waterpark

Hilton Garden Inn Orlando Airport

Hilton Garden Inn Orlando Airport
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
8.8 out of 10, Excellent, (1,022 reviews)
"Really clean hotel, great staff."
Canada
Sheryl
The price is RM330
RM372 total
includes taxes & fees
31 May - 1 Jun
Hilton Garden Inn Orlando Airport

Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.5 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (3,010 reviews)
"Nice place to stay"
United States
LaToya
The price is RM431
RM485 total
includes taxes & fees
7 Jun - 8 Jun
Hyatt House Orlando Airport

Westgate Lakes Resort & Spa Universal Studios Area

Westgate Lakes Resort & Spa Universal Studios Area
4.0 star property
20.7 km from Lake Nona Medical City
8.4 out of 10, Very good, (6,493 reviews)
"Great stay"
United States
Hector
The price is RM388
RM570 total
includes taxes & fees
25 May - 26 May
Westgate Lakes Resort & Spa Universal Studios Area

Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,677 reviews)
"Very clean and kind staff good breakfast"
United States
Brittany
The price is RM402
RM452 total
includes taxes & fees
24 May - 25 May
Hampton Inn & Suites Orlando Airport @ Gateway Village

Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3,978 reviews)
"Breakfast was good , we love the waffle"
United States
Ana
The price is RM353
RM397 total
includes taxes & fees
26 May - 27 May
Wingate by Wyndham - Orlando International Airport

Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort
3.5 star property
Florida Center, 22.2 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (6,829 reviews)
"I love this hotel very nice clean and great place to stay with family "
United States
Deijah
The price is RM596
RM671 total
includes taxes & fees
25 May - 26 May
Universal's Cabana Bay Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

Downtown Orlando

One of the most popular neighborhoods in Florida, this bustling area is full of art galleries, shops, bars and restaurants.

Top Lake Nona Medical City Hotel Reviews

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.
What's the best accommodation in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels will I find in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.
What is there to do around this Orlando neighbourhood?
Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Moss Park are a couple of other sights to visit.

Explore a world of travel with Expedia