Uptown - Upper Duval
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Historic Key West Old Town Trolley Hop-On Hop-Off Tour
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
Half-Day Key West's Ultimate Sandbar Adventure with Mangrove Kayak Tour
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
Bucket-List Parasailing In Downtown Key West - Highest & Longest Rides
Key West Afternoon At The Reef Snorkeling Adventure with Open Bar!
Top hotels in Uptown - Upper Duval
Southernmost Beach Resort and Guesthouses
Beautiful property. Great room with a porch w ocean view. Very clean. Loved hearing the roosters everywhere. Shore Pool is great! Bartender great! Breakfast great at the hotel restaurant. The location of the hotel is close to everything, Duval St, restaurants and shopping. Recommend a golf cart for ...
Reviewed on 9 Feb 2026
The Reach Key West, Curio Collection by Hilton
Location
Reviewed on 9 Feb 2026
The Southernmost Inn - Adults Only
Such a special & quirky inn. Very nice rooms with great amenities!! We loved discovering the many different ways to get around the grounds. The Happy Hour every evening is very nice.
Reviewed on 11 Feb 2026
Southwinds Motel
Friendly and helpful staff.
Reviewed on 11 Feb 2026
Douglas House
The room was beautiful. The staff were helpful and super friendly.
Reviewed on 9 Feb 2026
Santa Maria Suites
The staff was very helpful and courteous Amenities was good. One guest slept on the sofa. There was no closet space downstairs. She shared the closet on the second floor which was not always convenient
Reviewed on 11 Feb 2026
Check Uptown - Upper Duval hotel availability
Other neighbourhoods around Uptown - Upper Duval
Old Town Key West
While visiting Old Town Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.
Bahama Village
Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.
Key West Historic District
Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Ernest Hemingway Home and Museum.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
White Street Gallery District
If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Clarence S. Higgs Memorial Beach Park.
