A river, a large white building, and a cityscape.

Jackson hotels from RM285

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
15 Aug - 16 Aug
Tomorrow
16 Aug - 17 Aug
Next weekend
21 Aug - 23 Aug
In two weeks
28 Aug - 30 Aug

Filter by

Star rating

Guest rating

Our top choices for Jackson hotels

Breakfast included
Hotel
Reserve now, pay later
Motel
Pet friendly

1. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Kevin
RM344
RM372 total
includes taxes & fees
20 Aug - 21 Aug
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

2. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Jamie
RM327
RM346 total
includes taxes & fees
23 Aug - 24 Aug
Drury Inn & Suites Jackson MO

3. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
United States
VICTORIA
RM341
RM369 total
includes taxes & fees
13 Sept - 14 Sept
Comfort Suites Jackson-Cape Girardeau

4. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Gwendolyn
RM365
RM416 total
includes taxes & fees
24 Aug - 25 Aug
Tru By Hilton Cape Girardeau

5. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Cheryl
RM368
RM415 total
includes taxes & fees
21 Aug - 22 Aug
Drury Inn & Suites Cape Girardeau

6. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
JoAnn
RM409
RM461 total
includes taxes & fees
6 Sept - 7 Sept
Drury Plaza Hotel Cape Girardeau Conference Center

7. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
Cris
RM421
RM475 total
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

8. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Bonnie
RM294
RM332 total
includes taxes & fees
7 Sept - 8 Sept
Pear Tree Inn Cape Girardeau West

9. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Stephen
RM252
RM285 total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Cape Girardeau North

10. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
RM432
RM488 total
includes taxes & fees
2 Sept - 3 Sept
Hampton Inn Cape Girardeau I 55 East

11. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Heather
RM413
RM466 total
includes taxes & fees
20 Aug - 21 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau

12. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Taylor
RM511
RM579 total
includes taxes & fees
6 Sept - 7 Sept
Courtyard by Marriott Cape Girardeau Downtown

13. The Riverview

The Riverview
Cape Girardeau
United States
James
RM467
RM527 total
includes taxes & fees
18 Aug - 19 Aug
The Riverview

14. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
RM339
RM405 total
includes taxes & fees
23 Aug - 24 Aug
Candlewood Suites Cape Girardeau by IHG

15. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
United States
Joshua
RM286
RM334 total
includes taxes & fees
5 Sept - 6 Sept
Town House Inn Cape Giradreau

16. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
RM344
RM374 total
includes taxes & fees
12 Sept - 13 Sept
EC Reed's Mercantile and Hotel

17. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
United States
Jacalyn
RM372
RM426 total
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express & Suites Perryville by IHG

18. Perryville RV Resort

Perryville RV Resort
Perryville
United States
Von
RM271
RM311 total
includes taxes & fees
16 Aug - 17 Aug
Perryville RV Resort

19. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
Perryville
United States
Angela
RM274
RM314 total
includes taxes & fees
15 Sept - 16 Sept
Super 8 by Wyndham Perryville

20. Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
Perryville
United States
Wanda
RM276
RM316 total
includes taxes & fees
16 Aug - 17 Aug
Days Inn by Wyndham Perryville
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Jackson attractions

Litz Park

8.6/10 (14 reviews)
This serene community park features a 2-acre lake encircled by a scenic walking trail. Tennis courts, basketball courts, and an 18-hole disc golf course offer active recreation options for visitors.
See properties

Indian Creek Wild Area

Indian Creek Wild Area offers 12 miles of scenic trails through diverse terrain for hikers, bikers, and horseback riders. Experience natural serenity through forested paths and open spaces away from urban bustle.
See properties

Lake Boutin

This 20-acre reservoir offers tranquil fishing and swimming surrounded by lush Missouri forest. Hike the 2.6-mile shoreline trail to spot wildlife and discover remnants of historic homesteads.
See properties

Vancill Hollow Natural Area

Explore a rare Appalachian-like forest ecosystem with beech trees and cucumber magnolias in this rugged 300-acre preserve. Bring a compass for off-trail adventures among diverse wildlife and towering 300-foot bluffs.
See properties

Learn more about Jackson

Stroll through the charming city centre and visit the historic courthouse, where you can learn about Jackson's rich past. Outdoor enthusiasts will love exploring nearby Trail of Tears State Park, offering hiking trails and scenic Mississippi River views.

See all hotels in Jackson
A historic building with a clock tower, surrounded by lush green grass and trees.

Top Jackson Hotel Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

8/10 Good
"Bed was awesome sleep great but a lot of noise"
Delphia 1-night trip
Posted 7 hours ago
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"Was nothing to dislike. Was nice to have many eating options within a safe walking distance."
Tresa 3-night trip
Posted 8 hours ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Best hotel so far great customer service great breakfast awesome kickback very nice and clean love the roof top"
ERICA 2-night trip
Posted 15 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

8/10 Good
"The staff for breakfast was wonderful. The hotel was fully booked. The staff was able to keep up with the demand of food. Our room did not look like it had been cleaned. There was food on floor and on pull out couch. The sheets had stains on them. Unfortunately with them being fully there wasn't much they could do. We did check in around 10pm and front desk person did offer to clean it. The housekeeping was supposed to clean it next morning. Unfortunately the only thing they did was pick up dirty and replace with clean ones."
Bobby 2-night trip
Posted 19 hours ago
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"would stay again. quiet and clean, nothing fancy"
Karen 1-night trip
Posted 20 hours ago
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent
"Property was clean a room was stocked. Had microwave refrigerator and a stove refrigerator had working ice maker. Great room for the price"
GISELE 2-night trip
Posted 1 day ago
Candlewood Suites Cape Girardeau by IHG
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Clean rooms and delicious buffet"
Patricia and Timothy 1-night trip
Posted 2 days ago
Drury Inn & Suites Cape Girardeau
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

10/10 Excellent
"Clean"
Kara 1-night trip
Posted 4 days ago
Tru By Hilton Cape Girardeau
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

10/10 Excellent
"Its always a peaceful stay for me ๐Ÿ’—"
OCTAVIS DARON 1-night trip
Posted 4 days ago
Town House Inn Cape Giradreau

Frequently asked questions

What's the best place to stay in Jackson?
Based on our traveller data, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau is one of the top choices for your stay. This hotel offers free breakfast and an indoor pool. Other good choices for your visit include Drury Inn & Suites Jackson MO and Comfort Suites Jackson-Cape Girardeau. See all available top hotels, or vacation rentals in Jackson.
If I need to cancel my hotel reservation in Jackson, will I receive a refund?
Yes! The majority of hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Jackson.
What's the best family accommodation in Jackson?
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau is a hotel with an indoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are fun for children of all ages. Find more child-friendly accommodations in Jackson.
What's the best LGBTQ-friendly accommodation in Jackson?
Drury Inn & Suites Jackson MO is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. See all available hotels listed as LGBTQ-friendly in Jackson.
What's the best dog-friendly accommodation option in Jackson?
Drury Inn & Suites Jackson MO is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. See more pet-friendly hotel accommodations in Jackson.
What are some accommodation options with pools in Jackson?
Comfort Suites Jackson-Cape Girardeau is a top hotel with an indoor pool, free buffet breakfast and free WiFi. View all hotels with pools in Jackson.
What is staying in Jackson like?
Visitors to Jackson will definitely enjoy the restaurants. Tourists can also enjoy the city's shopping, wineries and coffee shops. In Jackson, there are 10 hotels and other accommodation options to choose from. Find out more about Jackson.
What is there to see in Jackson?
The picturesque setting of Mississippi River and Lake Boutin exemplify the area's natural beauty. A couple of additional sights to add to your itinerary are Trail of Tears State Park and Indian Creek Wild Area. Take a look at what more there is to see and do in Expedia's Jackson guide.
What's the seasonal weather like in Jackson?
The hottest months are usually July and August, with an average temperature of 24ยฐC, while the coldest months are January and February, with an average of 4ยฐC. Average annual precipitation for Jackson is 1439 mm.

Explore a world of travel with Expedia